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obstruction (as determined by simultaneous polysomnography). Results: 20 obstructive episodes met the inclusion criteria. Mean O2 at the beginning (B) of the events was 95± 2.6%, nadir (N) 86± 4.1% and recovery (R) 95± 2.3%. ERP changes were dynamic but not different at the 3 time points (p= 0.07). CT across the CS was not different for S1, however, was significantly different for S2 (134± 30ms(B) vs. 148± 26ms(N) vs. 147± 40ms(R); p= 0.01). Lateral CT significantly changed for S1 (119± 20ms(B) vs. 126± 18ms(N) vs. 123± 20ms(R)) and S2 (177± 44ms(B) vs. 207± 38ms(N) vs. 207± 48ms(R); p= 0.03) measures. Local conduction delay (CD=A1A2−S1S2)was significantly different at the distal CS (63± 20ms(B) vs. 70± 15ms(N) vs. 74± 24ms(R); p= 0.01) and lateral RA (78± 26ms(B) vs. 97± 21ms(N) vs. 92± 30ms(R); p< 0.001). Conclusion: Acute obstruction during sleep apnoea results in significant atrial remodelling characterized by slowing of conduction during obstruction and incomplete recovery after the event. These changes may account in part for the development of AF in association with clinical OSA. doi:10.1016/j.hlc.2010.06.921

Background: Incessant focal atrial tachycardia (AT)may be complicated by LV dysfunction. The aim was to characterise the incidence, ECG and EP features of incessant focal AT and identify predictors of tachycardia mediated cardiomyopathy (TCM). Methods: 82 of 345 (24%) pts with focal AT presenting for radiofrequency ablation between 1997 and 2008 were incessant. Incessant AT was defined as continuous tachycardia or recurrent paroxysms of tachycardia separated by ≤2 sinus beats. Results: The mean age was 42± 20 years, 57% were male and mean symptom duration was 5± 7 years. TCM was present in 30/82 (37%), defined as LVEF