1. Effect of Out‐of‐Pocket Cost on Medication Initiation, Adherence, and Persistence among Patients with Type 2 Diabetes: The Diabetes Study of Northern California (DISTANCE)
- Author
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Karter, Andrew J, Parker, Melissa M, Solomon, Matthew D, Lyles, Courtney R, Adams, Alyce S, Moffet, Howard H, and Reed, Mary E
- Subjects
Health Services and Systems ,Health Sciences ,Aging ,Behavioral and Social Science ,Prevention ,Health Services ,Clinical Research ,Diabetes ,Metabolic and endocrine ,Good Health and Well Being ,Adult ,Aged ,California ,Comorbidity ,Cost Sharing ,Diabetes Mellitus ,Type 2 ,Female ,Financing ,Personal ,Health Expenditures ,Humans ,Hypoglycemic Agents ,Male ,Medication Adherence ,Middle Aged ,Socioeconomic Factors ,Adherence ,medical expenditures ,pharmacy benefits ,out-of-pocket costs ,Public Health and Health Services ,Policy and Administration ,Health Policy & Services ,Health services and systems ,Policy and administration - Abstract
ObjectiveTo estimate the effect of out-of-pocket (OOP) cost on nonadherence to classes of cardiometabolic medications among patients with diabetes.Data sources/settingElectronic health records from a large, health care delivery system for 223,730 patients with diabetes prescribed 842,899 new cardiometabolic medications during 2006-2012.Study designObservational, new prescription cohort study of the effect of OOP cost on medication initiation and adherence.Data collectionAdherence and OOP costs were based on pharmacy dispensing records and benefits.Principal findingsPrimary nonadherence (never dispensed) increased monotonically with OOP cost after adjusting for demographics, neighborhood socioeconomic status, Medicare, medical financial assistance, OOP maximum, deductibles, mail order pharmacy incentive and use, drug type, generic or brand, day's supply, and comorbidity index; 7 percent were never dispensed the new medication when OOP cost ≥$11, 5 percent with OOP cost of $1-$10, and 3 percent when the medication was free of charge (p
- Published
- 2018