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Your search keyword '"Hanai, Nobuhiro"' showing total 8 results
Start Over Author "Hanai, Nobuhiro" Journal head & neck
8 results on '"Hanai, Nobuhiro"'

1. Extent of thyroidectomy and paratracheal lymph node dissection in total pharyngolaryngectomy for pyriform sinus cancer, and recurrence, survival, and postoperative hypoparathyroidism: A multicenter retrospective study

Author

Ariizumi, Yosuke, primary, Hanai, Nobuhiro, additional, Asakage, Takahiro, additional, Seto, Akira, additional, Tomioka, Toshifumi, additional, Miyabe, Junji, additional, Kessoku, Hisashi, additional, Mukaigawa, Takashi, additional, Omura, Go, additional, Teshima, Masanori, additional, Nishikawa, Daisuke, additional, Saito, Yuki, additional, Asada, Yukinori, additional, Fujisawa, Takuo, additional, Makino, Takuma, additional, Nishino, Hiroshi, additional, Sano, Daisuke, additional, Nakahira, Mitsuhiko, additional, Tokashiki, Kunihiko, additional, Uemura, Hirokazu, additional, Ueda, Tsutomu, additional, Sakai, Akihiro, additional, Masuda, Muneyuki, additional, Tsujikawa, Takahiro, additional, Hiei, Yusuke, additional, Nishio, Naoki, additional, Matsui, Hidetoshi, additional, Kiyota, Naomi, additional, and Homma, Akihiro, additional

Published
2023
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2. Extent of thyroidectomy and paratracheal lymph node dissection in total pharyngolaryngectomy for pyriform sinus cancer, and recurrence, survival, and postoperative hypoparathyroidism: A multicenter retrospective study.

Author

Ariizumi, Yosuke, Hanai, Nobuhiro, Asakage, Takahiro, Seto, Akira, Tomioka, Toshifumi, Miyabe, Junji, Kessoku, Hisashi, Mukaigawa, Takashi, Omura, Go, Teshima, Masanori, Nishikawa, Daisuke, Saito, Yuki, Asada, Yukinori, Fujisawa, Takuo, Makino, Takuma, Nishino, Hiroshi, Sano, Daisuke, Nakahira, Mitsuhiko, Tokashiki, Kunihiko, and Uemura, Hirokazu

Subjects
LYMPHADENECTOMY, HYPOPARATHYROIDISM, THYROIDECTOMY, HYPOPHARYNGEAL cancer, HEMITHYROIDECTOMY, SINUS augmentation, RETROSPECTIVE studies
Abstract

Background: Total pharyngolaryngectomy (TPL) is standard treatment for hypopharyngeal cancer. However, extensive thyroidectomy and paratracheal nodal dissection (PTND) can cause hypoparathyroidism. We sought to determine the optimum extent of resection. Methods: We analyzed the clinicopathological information of 161 pyriform sinus cancer patients undergoing TPL from 25 Japanese institutions. Rates of recurrence and risk factors for hypoparathyroidism, as well as incidence of pathological contralateral level VI nodal metastasis and stomal recurrence, were investigated. Results: The extent of thyroidectomy and nodal dissection were not independent risk factors for recurrence. Incidences of contralateral level VI nodal involvement and stomal recurrence were 1.8% and 1.2%, respectively. Patients undergoing hemithyroidectomy/ipsilateral PTND did not develop stomal recurrence and had the lowest incidence of hypoparathyroidism. Prognosis in patients without tracheostomy prior to hemithyroidectomy/ipsilateral PTND was comparable to that with more extensive resections. Conclusions: Hemithyroidectomy/ipsilateral PTND may be sufficient for pyriform sinus cancer cases without tracheostomy. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Two-year follow-up of a randomized phase III clinical trial of nivolumab vs. the investigator's choice of therapy in the Asian population for recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141)

Author

Yen, Chia-Jui, Kiyota, Naomi, Hanai, Nobuhiro, Takahashi, Shunji, Yokota, Tomoya, Iwae, Shigemichi, Shimizu, Yasushi, Hong, Ruey-Long, Goto, Masahiro, Kang, Jin-Hyoung, Li, Wing Sum Kenneth, Ferris, Robert L., Gillison, Maura, Endo, Toshimitsu, Jayaprakash, Vijayvel, and Tahara, Makoto

Subjects
nivolumab, squamous cell carcinoma of the head and neck, Asian population, clinical trial, immunotherapy
Abstract

Background The present study evaluated the 2-year survival of the Asian population in the CheckMate 141 trial. Methods The CheckMate 141 trial included patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN). In the present study, 34 Asian patients (nivolumab group: 23 patients; investigator's choice of therapy [IC] group: 11 patients) were analyzed. Results The median overall survival (OS) was 12.1 and 6.2 months for the nivolumab and IC groups, respectively. The estimated 2-year OS rates were 22.7% and 0% for the nivolumab and IC groups, respectively. In the nivolumab group, the patients with any treatment-related adverse events (TRAEs), including skin-related disorders, showed better OS than the patients without any TRAEs. Conclusions Nivolumab demonstrated prolonged OS benefits in the Asian population with platinum-refractory R/M SCCHN and a favorable safety profile. TRAEs, including skin-related disorders, may be favorable prognostic factors for nivolumab efficacy. Clinical trial registration NCT02105636.

Published
2020

5. Sites of invasion of cancer of the external auditory canal predicting oncologic outcomes

Author

Shiga, Kiyoto, primary, Nibu, Ken‐ichi, additional, Fujimoto, Yasushi, additional, Asakage, Takahiro, additional, Homma, Akihiro, additional, Mitani, Hiroki, additional, Ogawa, Takenori, additional, Okami, Kenji, additional, Murono, Shigeyuki, additional, Hirano, Shigeru, additional, Ueda, Tsutomu, additional, Hanai, Nobuhiro, additional, Tsukahara, Kiyoaki, additional, Ota, Ichiro, additional, Yoshimoto, Seiichi, additional, Shinozaki, Takeshi, additional, Iwae, Shigemichi, additional, Katagiri, Katsunori, additional, Saito, Daisuke, additional, Kiyota, Naomi, additional, Tahara, Makoto, additional, Takahashi, Fumiaki, additional, and Hayashi, Ryuichi, additional

Published
2021
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7. Evaluation of the modified Pittsburgh classification for predicting the disease‐free survival outcome of squamous cell carcinoma of the external auditory canal

Author

Nabuurs, Cindy H., primary, Kievit, Wietske, additional, Labbé, Nilou, additional, Leemans, C. René, additional, Smit, Conrad F. G. M., additional, Brekel, Michiel W. M., additional, Pauw, Robert J., additional, Laan, Bernard F. A. M., additional, Jansen, Jeroen C., additional, Lacko, Martin, additional, Braunius, Weibel W., additional, Morita, Shinya, additional, Wierzbicka, Małgorzata, additional, Matoba, Takuma, additional, Hanai, Nobuhiro, additional, Takes, Robert P., additional, and Kunst, Henricus P. M., additional

Published
2020
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8. Central pathology review of salivary gland adenoid cystic carcinoma

Author

Ueda, Kaori, primary, Murase, Takayuki, additional, Nagao, Toshitaka, additional, Kusafuka, Kimihide, additional, Urano, Makoto, additional, Yamamoto, Hidetaka, additional, Nakaguro, Masato, additional, Taguchi, Ken‐ichi, additional, Masaki, Ayako, additional, Hirai, Hideaki, additional, Kawakita, Daisuke, additional, Tsukahara, Kiyoaki, additional, Hato, Naohito, additional, Nagao, Toru, additional, Fujimoto, Yasushi, additional, Sakurai, Kazuo, additional, Hanai, Nobuhiro, additional, Kano, Satoshi, additional, Onitsuka, Tetsuro, additional, Okami, Kenji, additional, Nibu, Ken‐ichi, additional, Tada, Yuichiro, additional, Kawata, Ryo, additional, and Inagaki, Hiroshi, additional

Published
2020
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