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1. DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype.

Author

Nangalia J, Nice FL, Wedge DC, Godfrey AL, Grinfeld J, Thakker C, Massie CE, Baxter J, Sewell D, Silber Y, Campbell PJ, and Green AR

Subjects
DNA Methyltransferase 3A, Female, Humans, Male, DNA (Cytosine-5-)-Methyltransferases genetics, Hematologic Neoplasms enzymology, Hematologic Neoplasms genetics, Mutation, Myeloproliferative Disorders enzymology, Myeloproliferative Disorders genetics, Neoplasm Proteins genetics
Published
2015
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