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The evaluation of groundwater quality is an imperative part of water security and plays a significant role in ensuring its sustainable development . The present paper reveals the quality of groundwater of Kanker district situated in Chhattisgarh state, India. Groundwater samples from different regions were collected to observe the seasonal variation in uranium concentration. The spatial distribution of major parameters and hydrochemical facies was described by Geographic Information System based maps, correlation coefficient , box plot, and piper diagrams. The uranium concentration ranges from 0.5 to 69.9 μg/L and 0.5–87.9 μg/L with the mean value of 4.8 μg/L and 6.8 μg/L in winter and summer season respectively. The uranium concentrations for the samples taken from one area in winter and two areas in summer have been found to be slightly higher than the permissible limit of 60 μg/L recommended by the Atomic Energy Regulatory Board. The seasonal variation of uranium in groundwater depends upon the rainfall recharge and precipitation conditions of the geological formation and the environment. In certain regions; it is observed that the total hardness, calcium, magnesium and total alkalinity (bicarbonate) were found higher than the acceptable limit prescribed by the Bureau of Indian Standards. Mixed type behaviors of tested samples were showed by the piper diagrams. Uranium exhibits a strong correlation with magnesium (r > 0.7) in both the seasons.