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Start Over Author "O'Neill, Keith" Journal genome research
1 results on '"O'Neill, Keith"'

1. Assembly of polymorphic genomes: Algorithms and application to Ciona savignyi

Author

Vinson, Jade P., Jaffe, David B., O'Neill, Keith, Karlsson, Elinor K., Stange-Thomann, Nicloe, Anderson, Scott, Mesirov, Jill P., Satoh, Nori, Satou, Yutaka, Nusbaum, Chad, Birren, Bruce, Galagan, James E., and Lander, Eric S.

Subjects
Genetic polymorphisms -- Research, Haplotypes -- Research, Health
Abstract

A method for assembling highly polymorphic diploid genomes that involves assembling the two haplotypes separately and then merging them to obtain a reference sequence is presented. This method represented loci in a single copy more reliably and achieved greater contiguity than a conventional whole-genome assembly method.

Published
2005

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