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Your search keyword '"Carter, Nigel P."' showing total 5 results
Start Over Author "Carter, Nigel P." Journal genome research
5 results on '"Carter, Nigel P."'

1. Copy number variation and evolution in humans and chimpanzees

Author

Perry, George H., Fengtang Yang, Marques-Bonet, Tomas, Murphy, Carly, Fitzgerald, Tomas, Lee, Arthur S., Hyland, Courtney, Stone, Anne C., Hurles, Matthew E., Tuler-Smith, Chris, Eichler, Evan E., Carter, Nigel P., Lee, Charles, and Redon, Richard

Subjects
Chimpanzees -- Genetic aspects, Human genome -- Analysis, Polymerase chain reaction -- Usage, Population genetics -- Analysis, Health
Published
2008

2. An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

Author

Rakyan, Vardhman K., Down, Thomas A., Thorne, Natalie P., Flicek, Paul, Kulesha, Eugene, Graf, Stefan, Tomazou, Eleni M., Backdahl, Liselotte, Johnson, Nathan, Herberth, Marlis, Howe, Kevin L., Jackson, David K., Miretti, Marcos M., Fiegler, Heike, Marioni, John C., Birney, Ewan, Hubbard. Tim J.P., Carter, Nigel P., Tavare, Simon, and Beck, Stephan

Subjects
Methylation -- Analysis, Genomics -- Research, DNA -- Chemical properties, Health
Abstract

The article discusses a novel integrated resource, which is used for the genome-wide identification and analysis of the human tissue-specific differentially methylated regions (tDMRs). These tDMRs are shown to play an extremely significant role in the cellular identity and regulation of tissue-specific genome function.

Published
2008

3. The landscape of histone modifications across 1% of the human genome in five human cell lines

Author

Koch, Christoph M., Clelland, Gayle K., James, Keith D., Dhami, Pawandeep, Vetrie, David, Andrews, Robert M., Lefebvre, Gregory C., Langford, Cordelia F., Dunham, Ian, Wilcox, Sarah, Flicek, Paul, Beare, David, Bruce, Alexander W., Zhiping Weng, Dillon, Shane C., Fowler, Joanna C., Dovey, oliver M., Birney, Ewan, Karaoz, Ulas, Couttet, Phillippe, Ellis, Peter D., and Carter, Nigel P.

Subjects
Histones -- Analysis, Cell lines -- Analysis, Genetic transcription -- Analysis, Health
Abstract

The study of modified maps of histone in five human cell lines reveals the differences in transcription of the different cell lines.

Published
2007

4. Copy number variation: New insights in genome diversity

Author

Freeman, Jennifer L., Perry, George H., Feuk, Lars, Redon, Richard, McCarroll, Steven A., Altshuler, David M., Hiroyuki Aburatani, Jones, Keith W., Tyler-Smith, Chris, Hurles, Matthew E., Carter, Nigel P., Scherer, Stephen W., and Lee, Charles

Subjects
Genetic variation -- Research, Gene mutations -- Research, Genetic disorders -- Research, Health
Abstract

Copy number variants (CNVs) account for a substantial amount of genetic variation in humans, and since many CNVs include genes that result in differential levels of gene expression, CNVs may account for a significant proportion of normal phenotypic variation. Efforts are directed toward a more comprehensive cataloging and characterization of CNVs that will provide the basis for determining how genomic diversity impacts biological function, evolution and common human diseases.

Published
2006

5. Accurate and reliable high-throughput detection of copy number variation in the human genome

Author

Fiegler, Heike, primary, Redon, Richard, additional, Andrews, Dan, additional, Scott, Carol, additional, Andrews, Robert, additional, Carder, Carol, additional, Clark, Richard, additional, Dovey, Oliver, additional, Ellis, Peter, additional, Feuk, Lars, additional, French, Lisa, additional, Hunt, Paul, additional, Kalaitzopoulos, Dimitrios, additional, Larkin, James, additional, Montgomery, Lyndal, additional, Perry, George H., additional, Plumb, Bob W., additional, Porter, Keith, additional, Rigby, Rachel E., additional, Rigler, Diane, additional, Valsesia, Armand, additional, Langford, Cordelia, additional, Humphray, Sean J., additional, Scherer, Stephen W., additional, Lee, Charles, additional, Hurles, Matthew E., additional, and Carter, Nigel P., additional

Published
2006
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