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Your search keyword '"Ellie Guardino"' showing total 2 results
Start Over Author "Ellie Guardino" Journal genome medicine
2 results on '"Ellie Guardino"'

1. Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach

Author

Zia Khan, Christian Hammer, Ellie Guardino, G. Scott Chandler, and Matthew L. Albert

Subjects
Medicine, Genetics, QH426-470
Abstract

Editorial summary Personalized care of cancer patients undergoing treatment with immune checkpoint inhibitors will require approaches that can predict their susceptibility to immune-related adverse events. Understanding the role of germline genetic factors in determining individual responses to immunotherapy will deepen our understanding of immune toxicity and, importantly, it may lead to tools for identifying patients who are at risk.

Published
2019
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2. Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach

Author

Matthew L. Albert, Christian Hammer, Zia Khan, Ellie Guardino, and G. Scott Chandler

Subjects
0301 basic medicine, lcsh:QH426-470, medicine.medical_treatment, Systems biology, lcsh:Medicine, Bioinformatics, Germline, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antineoplastic Agents, Immunological, Neoplasms, Genetics, medicine, Animals, Humans, Genetic Testing, Precision Medicine, Receptors, Immunologic, Adverse effect, Molecular Biology, Genetics (clinical), business.industry, lcsh:R, Comment, Cancer, Immunotherapy, biochemical phenomena, metabolism, and nutrition, medicine.disease, Human genetics, Immune checkpoint, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, bacteria, business, Genome-Wide Association Study
Abstract

Editorial summary Personalized care of cancer patients undergoing treatment with immune checkpoint inhibitors will require approaches that can predict their susceptibility to immune-related adverse events. Understanding the role of germline genetic factors in determining individual responses to immunotherapy will deepen our understanding of immune toxicity and, importantly, it may lead to tools for identifying patients who are at risk.

Published
2019

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