1. Die Diagnostik fetaler Virusinfektionen durch In-situ-Hybridisierung*
- Author
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Wolfgang Holzgreve, Yasmin Mehraein, Ursula Froster-Iskenius, Helga Rehder, Eberhard Schwinger, and H. Draeger
- Subjects
Pathology ,medicine.medical_specialty ,biology ,Parvovirus ,viruses ,Hybridization probe ,Varicella zoster virus ,virus diseases ,Obstetrics and Gynecology ,Prenatal diagnosis ,In situ hybridization ,biology.organism_classification ,medicine.disease_cause ,Virology ,Virus ,Herpesviridae ,Alphaherpesvirinae ,embryonic structures ,Maternity and Midwifery ,medicine ,reproductive and urinary physiology - Abstract
Non-radioactive in situ hybridization of formalin-fixed paraffin-embedded placental and foetal tissue, using virus-specific DNA or RNA probes, may be helpful for the diagnosis of foetal virus infection causing foetal hydrops, granulomatous placentitis and abortion. We present four cases of intrauterine CMV-, Parvo-B19- and Varicella-Zoster virus infection, in which this diagnostic method established detection of the virus.
- Published
- 1991
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