1. Factors Influencing Disability and Quality of Life during Treatment: A Cross-Sectional Study on IBD Patients
- Author
-
Carla Marinelli, Edoardo Savarino, Marco Inferrera, Greta Lorenzon, Alessandra Rigo, Matteo Ghisa, Sonia Facchin, Renata D’Incà, and Fabiana Zingone
- Subjects
Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Background/Aim. Inflammatory bowel disease (IBD) is a chronic disorder affecting patients’ quality of life and increasing their disability. The aim of our study was to evaluate clinical and pharmacological factors associated with impaired quality of life and disability in a large cohort of IBD patients during IBD treatment. Methods. We consecutively and prospectively recruited all IBD patients referred to the IBD Unit of the “Azienda Ospedaliera” of Padua. Demographics and clinical information were collected, and all patients completed the IBD questionnaire (IBDQ) and the IBD-Disability Index (IBD-DI) questionnaire. A multivariate regression model and Spearman’s rank correlation coefficient were applied for detecting IBD-related variables relevant to disability and quality of life. Results. We included 435 IBD patients. Multivariate regression modelling identified active disease, anaemia, presence of extraintestinal manifestations, and Crohn subtype as independent predictors for both disability and poor quality of life. We observed a strong positive correlation between IBD-DI and IBDQ (r=0.84, p
- Published
- 2019
- Full Text
- View/download PDF