1. Technical Review on the Management of Eosinophilic Esophagitis: A Report From the AGA Institute and the Joint Task Force on Allergy-Immunology Practice Parameters
- Author
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Rank, Matthew A, Sharaf, Rajiv N, Furuta, Glenn T, Aceves, Seema S, Greenhawt, Matthew, Spergel, Jonathan M, Falck-Ytter, Yngve T, Dellon, Evan S, Institute, AGA, Chachu, Karen A, Day, Lukejohn, Lebwohl, Benjamin, Muniraj, Thiruvengadam, Patel, Amit, Peery, Anne F, Shah, Raj, Singh, Harminder, Singh, Siddharth, Spechler, Stuart J, Sultan, Shahnaz, Su, Grace L, Thrift, Aaron P, Weiss, Jennifer M, Weizman, Adam V, collaborators, Joint Task Force on Allergy-Immunology Practice Parameters, Bernstein, Jonathan A, Dinakar, Chitra, Golden, David BK, Khan, David A, Lieberman, Jay, Oppenheimer, John, Shaker, Marcus, Stukus, David R, Wallace, Dana V, and Wang, Julie
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Digestive Diseases ,Nutrition ,Food Allergies ,Clinical Research ,Administration ,Topical ,Adult ,Advisory Committees ,Age Factors ,Allergy and Immunology ,Child ,Dilatation ,Eosinophilic Esophagitis ,Eosinophils ,Esophagoscopy ,Evidence-Based Medicine ,Food Hypersensitivity ,Food ,Formulated ,Gastroenterology ,Glucocorticoids ,Humans ,Proton Pump Inhibitors ,Societies ,Medical ,Treatment Outcome ,United States ,AGA Institute. Electronic address: clinicalpractice@gastro.org ,Joint Task Force on Allergy-Immunology Practice Parameters collaborators. Electronic address: drdanawallace@gmail.com ,AGA Institute ,Joint Task Force on Allergy-Immunology Practice Parameters collaborators ,Biologic Therapy ,Corticosteroids ,Dietary Therapy ,Elemental Diet ,Elimination Diet ,Esophageal Dilation ,Proton Pump Inhibitor ,Swallowed Corticosteroids ,Targeted Elimination Diet ,Technical Review ,Neurosciences ,Paediatrics and Reproductive Medicine ,Gastroenterology & Hepatology ,Clinical sciences ,Nutrition and dietetics - Abstract
Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus. Many new studies have been reported recently that describe EoE management. An expert panel was convened by the American Gastroenterological Association Institute and the Joint Task Force on Allergy-Immunology Practice Parameters to provide a technical review to be used as the basis for an updated clinical guideline. This technical review was developed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework. Eighteen focused EoE management questions were considered, with 15 answered using the GRADE framework and 3 with a narrative summary. There is moderate certainty in the evidence that topical glucocorticosteroids effectively reduce esophageal eosinophil counts to
- Published
- 2020