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Your search keyword '"Kubes, Paul"' showing total 12 results
Start Over Author "Kubes, Paul" Journal gastroenterology
12 results on '"Kubes, Paul"'

3. Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Author

Hilscher, Moira B., primary, Sehrawat, Tejasav, additional, Arab, Juan P., additional, Zeng, Zhutian, additional, Gao, Jinhang, additional, Liu, Mengfei, additional, Kostallari, Enis, additional, Gao, Yandong, additional, Simonetto, Douglas A., additional, Yaqoob, Usman, additional, Cao, Sheng, additional, Revzin, Alexander, additional, Beyder, Arthur, additional, Wang, Rong A., additional, Kamath, Patrick S., additional, Kubes, Paul, additional, and Shah, Vijay H., additional

Published
2019
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6. Combination of Mass Cytometry and Imaging Analysis Reveals Origin, Location, and Functional Repopulation of Liver Myeloid Cells in Mice

Author

David, Bruna Araujo, primary, Rezende, Rafael Machado, additional, Antunes, Maísa Mota, additional, Santos, Mônica Morais, additional, Freitas Lopes, Maria Alice, additional, Diniz, Ariane Barros, additional, Sousa Pereira, Rafaela Vaz, additional, Marchesi, Sarah Cozzer, additional, Alvarenga, Débora Moreira, additional, Nakagaki, Brenda Naemi, additional, Araújo, Alan Moreira, additional, dos Reis, Daniela Silva, additional, Rocha, Renata Monti, additional, Marques, Pedro Elias, additional, Lee, Woo-Yong, additional, Deniset, Justin, additional, Liew, Pei Xiong, additional, Rubino, Stephen, additional, Cox, Laura, additional, Pinho, Vanessa, additional, Cunha, Thiago Mattar, additional, Fernandes, Gabriel Rocha, additional, Oliveira, André Gustavo, additional, Teixeira, Mauro Martins, additional, Kubes, Paul, additional, and Menezes, Gustavo Batista, additional

Published
2016
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12. Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis

Author

Arndt, Holger, Russell, Janice B., Kurose, Iwao, Kubes, Paul, and Granger, D.Neil

Abstract

Background:Inhibitors of nitric oxide production promote leukocyte adherence and emigration in postcapillary venules. The objective of this study was to determine if the enhanced leukocyte adherence and emigration associated with inhibition of NO production involves inflammatory agents such as platelet-activating factor (PAF) and leukotriene B4(LTB4) and/or phospholipase A2(PLA2). Methods:The rat mesentery was superfused with the inhibitor of NO production NGnitro-l-arginine methyl ester (l-NAME) either alone or in combination with WEB2086 (PAF receptor antagonist), SC41930 (LTB4receptor antagonist), or quinacrine (PLA2inhibitor). The number of adherent and emigrated leukocytes, leukocyte rolling velocity, erythrocyte velocity, venular blood flow, and shear rate were monitored in mesenteric venules. Results:l-NAME alone induced a dramatic increase in leukocyte adherence (10-fold) and emigration (4-fold). Treatment with SC41930 significantly reduced, whereas either WEB2086 or quinacrine completely abolished, the increased leukocyte adherence and emigration induced by l-NAME. Conclusions:These observations suggest that the increased leukocyte adherence and emigration associated with inhibition of NO synthesis involves PLA2activation and is mediated by PAF and LTB4.

Published
1993
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