1. Clinicopathological profile and outcomes of anorectal melanoma from a tertiary care center in India
- Author
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Vikas Garg, Sameer Rastogi, Harshal Aswar, Shamim A Shamim, Ekta Dhamija, Adarsh Barwad, Rambha Pandey, Rajesh Panwar, and Ashish Upadhyay
- Subjects
anal ,anorectal ,chemotherapy ,immunotherapy ,melanoma ,mucosal ,Medicine ,Medicine (General) ,R5-920 - Abstract
Background: Anorectal melanoma (AM) is a rare subtype of melanoma. Aim: To study the clinic–pathologic features and outcomes in patients with AM. Materials & methods: Clinical, pathologic findings and outcomes of patients with AM were recorded. Results: Twenty-seven patients with AM were identified with median age of 57 years. Most patients presented in stage III (44.4%). Lymph node involvement was seen in 70.4%. The response to chemotherapy and immunotherapy was 16.6 and 25.0%, respectively. At a median follow up of 11 months, median overall survival was 30 months. Ballantine stage 3 and weight loss at presentation were predictors of poor survival. Conclusion: AM presents at an advanced stage with lymph node and distant metastasis.
- Published
- 2022
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