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Numerical simulation code such as commercial CFD one, ANSYS-CFX was studied and validated with the previous experimental data for magnetohydrodynamics (MHD) analysis in the liquid metal breeder flow of the Korean Test Blanket Module (TBM) considering the ITER operation conditions. And, a system code for safety analysis was developed with the MARS-FR (Multi-dimensional Analysis Reactor Safety for Fusion Reactor) in this study, whose base code was MARS and it was developed for commercial pressurized water reactor and gas cooled reactor in Korea. First, with the selected benchmarking problem with previous experimental studies and analytic solution, ANSYS-CFX was validated and evaluated. It shows a good agreement with the pressure loss prediction in MHD flow. Second, the system code was developed to predict the MHD effect for the one dimensional flow analysis based on a MHD solution which Miyazaki derived and has semi-implicit scheme to a flow direction. This study shows good agreement between ANSYS-CFX MHD prediction and experimental results as a validation, and the developed system code presents good performance of prediction in MHD pressure loss.