Search

This study investigated the effects of oligonol intake on cortisol, interleukin (IL)-1β, and IL-6 concentrations in the serum as well as body temperature after leg immersion into hot water. Thirteen healthy male volunteers participated in this study. Each subject received oligonol (100 mg) before leg immersion into hot water. Skin and tympanic temperatures were measured and mean body temperatures were calculated. Serum concentrations of cortisol, IL-1β, and IL-6 were measured during and after leg immersion. Individuals who received oligonol had significantly decreased cortisol concentrations and serum levels of IL-1β and IL-6 compared to ones who did not receive oligonol. In addition, skin, tympanic, and mean body temperatures of oligonol group were maintained at lower degree overall recovery period compared with placebo group. These results suggest that oral oligonol intake before hot water immersion had a significant effect on inhibition of pyrogenic cytokine response and thermal suppression in healthy young men.

This study measured caffeine-induced changes in activated sweat gland density (ASGD) and fat oxidation using a randomized crossover design with 10 healthy volunteers given caffeine (Caffe-I, 3 mg/kg ingested 30 min before experiment) and non-caffeine (No-Caff). Subjects were 173.0±3.2 cm in height, 72.5±4.3 kg in weight, and 21.5±2.5 years in age. All experiments were performed in an automated climate chamber (24.0±0.5°C, relative humidity 50±3%, air velocity less than 1 m/sec) between 2–5 p.m. The ASGD on the chest, upper arm, upper back, and lower back were measured (after 30 min running at 60% VO2max), and blood samples were taken (at 40 min before, immediately before and after 30 min running). Activated sweat gland density levels were higher in Caffe-I (Chest p

This study investigated the anti-inflammatory effects of Pellinus linteus (PL) extract supplementation in healthy young men. The subjects were 18 healthy young males 20 years of age that were given 1.5 L of 0.12% PL extract orally (n=8) or a placebo (control group, n=10) daily for 4 weeks. The body composition, the white blood cell (WBC) count and differential as well as the serum cortisol, interleukin (IL)-1β, and IL-6 concentrations were measured before and after the supplementation. Serum concentrations of cortisol and IL-1β at rest after oral supplementation were significantly decreased compared to before treatment (p