1. New triterpene glycosides from Ziziphi Spinosae Semen
- Author
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Xin-Sheng Yao, Yun-Long Hou, Dan Luo, Liu-Yuan Chen, Yi Dai, Bo Ding, and Yu Wang
- Subjects
Pharmacology ,chemistry.chemical_classification ,Neonatal rat ,Molecular Structure ,Glycoside ,Semen ,Ziziphus ,General Medicine ,Saponins ,Triterpenes ,Rats ,chemistry.chemical_compound ,chemistry ,Triterpene ,Drug Discovery ,Seeds ,Organic chemistry ,Animals ,Myocytes, Cardiac ,Glycosides ,Rats, Wistar ,Hydrogen peroxide ,Drugs, Chinese Herbal - Abstract
Four new dammarane-type triterpene glycosides, named jujubosides I-IV (1-4), were isolated from Ziziphi Spinosae Semen, along with seven known saponins (5-11). The structures of new compounds were established on the basis of extensive spectroscopic analysis. All compounds were evaluated for the effects on neonatal rat cardiomyocyte injury induced by hydrogen peroxide in vitro.
- Published
- 2013