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An alkaloid with novel skeleton, sinoscrewtine (1), has been isolated from the roots of Sinomenium acutum. Its structure was established by spectral analysis and X-ray crystallographic study, and its possible biosynthetic pathway was delivered. In vitro experiments, 1 showed weak injurious effects against H(2)O(2)/Aβ(25-35) induced oxidative injury in PC-12 cells and DPPH radical scavenging activity with IC(50) of 32.6μM., (Copyright © 2012 Elsevier B.V. All rights reserved.)

One new guaiane-type sesquiterpene (1) was isolated from Saussurea laniceps. The structure of the new compound was elucidated by spectroscopic data analysis. The immunomodulatory activity of compound 1 was evaluated. It was found that compound 1 showed significant inhibition for proliferation of murine T cells in vitro., (Copyright © 2010 Elsevier B.V. All rights reserved.)

Three new diterpenoids, pierisformosides G-I (1-3) and a diphenylamine derivative 4 have been isolated from the ethanol extract of Pieris formosa leaves, compound 1 being a new type seco-ring-A kaurane diterpene glucoside. Their structures were elucidated with the aid of NMR spectroscopy including two-dimensional-NMR techniques.

Three triterpenoid acids, nigranoic acid (1), manwuweizic acid (2), schisandronic acid (3), and other four compounds were isolated from the stems of Schisandra propinqua. Compounds 1 and 2 showed significant cytotoxic effect against human decidual cells and rat luteal cells in vitro.

Twelve constituents from Rhododendron latoucheae were isolated. Among them, compounds 1 and 2, named rhodolatouside A and B, respectively, are new iridoids.