4 results on '"Nap, A. W."'
Search Results
2. Tubal flushing with oil-based or water-based contrast at hysterosalpingography for infertility: long-term reproductive outcomes of a randomized trial.
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van Rijswijk, Joukje, van Welie, Nienke, Dreyer, Kim, Pham, Clarabelle T., Verhoeve, Harold R., Hoek, Annemieke, de Bruin, Jan Peter, Nap, Annemiek W., van Hooff, Machiel H.A., Goddijn, Mariëtte, Hooker, Angelo B., Bourdrez, Petra, van Dongen, Angelique J.C.M., van Rooij, Ilse A.J., van Rijnsaardt-Lukassen, Henrike G.M., van Golde, Ron J.T., van Heteren, Cathelijne F., Pelinck, Marie J., Duijn, Annette E.J., and Kaplan, Mesrure more...
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INFERTILITY , *BIRTH rate , *FEMALE infertility , *PREGNANCY , *CONFIDENCE intervals , *INFERTILITY treatment , *IRRIGATION (Medicine) , *RESEARCH , *PREDICTIVE tests , *HYSTEROSALPINGOGRAPHY , *TIME , *RESEARCH methodology , *CONTRAST media , *MEDICAL cooperation , *EVALUATION research , *PREGNANCY outcomes , *TREATMENT effectiveness , *COMPARATIVE studies , *FERTILITY , *HUMAN reproductive technology , *DRUG administration , *DRUG dosage - Abstract
Objective: To determine the impact of oil-based versus water-based contrast on pregnancy and live birth rates ≤5 years after hysterosalpingography (HSG) in infertile women.Design: A 5-year follow-up study of a multicenter randomized trial.Setting: Hospitals.Patient(s): Infertile women with an ovulatory cycle, 18-39 years of age, and having a low risk of tubal pathology.Intervention(s): Use of oil-based versus water-based contrast during HSG.Main Outcome Measure(s): Ongoing pregnancy, live births, time to ongoing pregnancy, second ongoing pregnancy.Result(s): A total of 1,119 women were randomly assigned to HSG with oil-based contrast (n = 557) or water-based contrast (n = 562). After 5 years, 444 of 555 women in the oil group (80.0%) and 419 of 559 women in the water group (75.0%) had an ongoing pregnancy (relative risk [RR] 1.07; 95% confidence interval [CI] 1.00-1.14), and 415 of 555 women in the oil group (74.8%) and 376 of 559 women in the water group (67.3%) had live births (RR 1.11; 95% CI 1.03-1.20). In the oil group, 228 pregnancies (41.1%) were conceived naturally versus 194 (34.7%) pregnancies in the water group (RR 1.18; 95% CI 1.02-1.38). The time to ongoing pregnancy was significantly shorter in the oil group versus the water group (10.0 vs. 13.7 months; hazard ratio, 1.25; 95% CI 1.09-1.43). No difference was found in the occurrence of a second ongoing pregnancy.Conclusion(s): During a 5-year time frame, ongoing pregnancy and live birth rates are higher after tubal flushing with oil-based contrast during HSG compared with water-based contrast. More pregnancies are naturally conceived and time to ongoing pregnancy is shorter after HSG with oil-based contrast.Clinical Trial Registration Number: Netherlands Trial Register (NTR) 3270 and NTR6577(www.trialregister.nl). [ABSTRACT FROM AUTHOR] more...- Published
- 2020
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3. Oil-based or water-based contrast for hysterosalpingography in infertile women: a cost-effectiveness analysis of a randomized controlled trial.
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van Rijswijk, Joukje, Pham, Clarabelle T., Dreyer, Kim, Verhoeve, Harold R., Hoek, Annemieke, de Bruin, Jan-Peter, Nap, Annemiek W., Wang, Rui, Lambalk, Cornelis B., Hompes, Peter G.A., Mijatovic, Velja, Karnon, Jonathan D., and Mol, Ben W. more...
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HYSTEROSALPINGOGRAPHY , *FEMALE infertility , *OVULATION , *COST effectiveness , *INFERTILITY treatment , *BIRTH rate , *GROWTH factors , *INFERTILITY , *MEDICAL cooperation , *RESEARCH , *STATISTICAL sampling , *VEGETABLE oils , *WATER , *RANDOMIZED controlled trials , *CONTRAST media , *DRUG administration , *DRUG dosage ,FALLOPIAN tube diseases - Abstract
Objective: To determine the cost effectiveness of the use of oil-based versus water-based contrast in infertile women undergoing hysterosalpingography (HSG).Design: Economic evaluation alongside a multicenter randomized trial.Setting: Hospitals.Patient(s): Infertile women with an ovulatory cycle, 18-39 years of age, low risk of tubal pathology.Intervention(s): Use of oil-based versus water-based contrast during HSG.Main Outcome Measure(s): Costs per additional ongoing pregnancy and per live birth within 6 months of randomization, incremental cost-effective ratios (ICERs).Result(s): A total of 1,119 women were randomized to HSG (oil-based contrast, n = 557; water-based contrast, n = 562). After HSG, most women had no additional treatment; a minority had IUI or IVF. In the oil group, 39.7% women had an ongoing pregnancy within 6 months of randomization versus 29.1% women in the water group. There was a 10.7% increase in the live birth rate in the oil group. For ongoing pregnancy, the mean costs per couple were US$2,014 in the oil group and US$1,144 in the water group, with a corresponding ICER of US$8,198 per additional ongoing pregnancy. For live birth, the mean costs per couple were US$11,532 in the oil group and US$8,310 in the water group, with a corresponding ICER of US$30,112 per additional live birth.Conclusion(s): Hysterosalpingography with oil-based contrast results in higher 6-month ongoing pregnancy and live birth rate. If society is willing to pay US$8,198 for an additional ongoing pregnancy, HSG with oil-based contrast is a cost-effective strategy compared with HSG with water-based contrast for infertile, ovulatory women at low risk for tubal pathology.Clinical Trial Registration Number: Dutch Trial Register, NTR 6577 (www.trialregister.nl). [ABSTRACT FROM AUTHOR] more...- Published
- 2018
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4. Pain cognition versus pain intensity in patients with endometriosis: toward personalized treatment.
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van Aken, Mieke A.W., Oosterman, Joukje M., van Rijn, C.M., Ferdek, Magdalena A., Ruigt, Gé S.F., Peeters, B.W.M.M., Braat, Didi D.M., and Nap, Annemiek W.
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ENDOMETRIOSIS , *QUALITY of life , *COGNITION , *MAGNETIC resonance imaging , *MEDICAL statistics , *PATIENTS , *ANXIETY diagnosis , *PELVIC pain diagnosis , *ANXIETY , *HEALTH surveys , *PELVIC pain , *PSYCHOLOGICAL tests , *QUESTIONNAIRES , *SURVEYS , *PAIN measurement , *CROSS-sectional method , *CASE-control method , *DISEASE complications , *PSYCHOLOGY - Abstract
Objective: To explore how pain intensity and pain cognition are related to health-related quality of life (HRQoL) in women with endometriosis.Design: Cross-sectional questionnaire-based survey.Setting: Multidisciplinary referral center.Patient(s): Women with laparoscopically and/or magnetic resonance imaging-proven endometriosis (n = 50) and healthy control women (n = 42).Intervention(s): For HRQoL, two questionnaires: the generic Short Form Health Survey (SF-36) and the Endometriosis Health Profile 30 (EHP-30). For pain cognition, three questionnaires: the Pain Catastrophizing Scale (PCS), the Pain Vigilance and Awareness Questionnaire (PVAQ), and the Pain Anxiety Symptoms Scale (PASS). For pain intensity, the verbal Numeric Rating Scale (NRS).Main Outcome Measure(s): Association between pain intensity and pain cognition with HRQoL in women with endometriosis, and the differences in HRQoL and pain cognition between women with endometriosis and healthy controls.Result(s): Health-related quality of life was statistically significantly impaired in women with endometriosis as compared with healthy control women. The variables of pain intensity and pain cognition were independent factors influencing the HRQoL of women with endometriosis. Patients with endometriosis had statistically significantly more negative pain cognition as compared with controls. They reported more pain anxiety and catastrophizing, and they were hypervigilant toward pain.Conclusion(s): Pain cognition is independently associated with the HRQoL in endometriosis patients. Clinicians should be aware of this phenomenon and may consider treating pain symptoms in a multidimensional, individualized way in which the psychological aspects are taken into account. In international guidelines on management of women with endometriosis more attention should be paid to the psychological aspects of care. [ABSTRACT FROM AUTHOR] more...- Published
- 2017
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