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Start Over Author "Grenga, Lucia" Journal fems microbiology letters
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3. The Escherichia coli FtsK functional domains involved in its interaction with its divisome protein partners.

Author

Grenga, Lucia, Luzi, Giuseppe, Paolozzi, Luciano, and Ghelardini, Patrizia

Subjects
*PROTEIN-protein interactions, *MOLECULAR association, *BACTERIAL cell surfaces, *CELL proliferation, *ESCHERICHIA coli, *CELL nuclei, *CELL division, *CHROMOSOMES, *CELL growth
Abstract

FtsK is a multifunctional protein involved in both cell division and chromosome segregation. As far as its role in cell division is concerned, FtsK is among the first divisome proteins that localizes at mid-cell, after FtsZ, FtsA and ZipA, and is required for the recruitment of the other divisome components. The ability of FtsK to interact with several cell division proteins, namely FtsZ, FtsQ, FtsL and FtsI, by the two-hybrid assay was already shown by our group. In this work, we describe the identification of the protein domain(s) involved in the interaction with the cell division partner proteins. The biological role of some interactions is also discussed. [ABSTRACT FROM AUTHOR]

Published
2008
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