Search

Your search keyword '"Ausems, Margreet G. E. M."' showing total 21 results
Start Over Author "Ausems, Margreet G. E. M." Journal familial cancer
21 results on '"Ausems, Margreet G. E. M."'

8. The development of an online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making: a usability and pilot study

Author

Reumkens, Kelly, Tummers, Marly H. E., Gietel-Habets, Joyce J. G., van Kuijk, Sander M. J., Aalfs, Cora M., van Asperen, Christi J., Ausems, Margreet G. E. M., Collée, Margriet, Dommering, Charlotte J., Kets, C. Marleen, van der Kolk, Lizet E., Oosterwijk, Jan C., Tjan-Heijnen, Vivianne C. G., van der Weijden, Trudy, de Die-Smulders, Christine E. M., and van Osch, Liesbeth A. D. M.

Published
2019
Full Text
View/download PDF

11. Healthcare professionals’ perspectives on implementation of universal tumor DNA testing in ovarian cancer patients: multidisciplinary focus groups

Author

Witjes, Vera M., primary, Braspenning, Jozé C. C., additional, Hoogerbrugge, Nicoline, additional, Smolders, Yvonne H. C. M., additional, Hermkens, Dorien M. A., additional, Mourits, Marian J. E., additional, Ligtenberg, Marjolijn J. L., additional, Ausems, Margreet G. E. M., additional, and de Hullu, Joanne A., additional

Published
2022
Full Text
View/download PDF

16. ‘We don’t know for sure’: discussion of uncertainty concerning multigene panel testing during initial cancer genetic consultations

Author

Medendorp, Niki M., primary, Hillen, Marij A., additional, van Maarschalkerweerd, Pomme E. A., additional, Aalfs, Cora M., additional, Ausems, Margreet G. E. M., additional, Verhoef, Senno, additional, van der Kolk, Lizet E., additional, Berger, Lieke P. V., additional, Wevers, Marijke R., additional, Wagner, Anja, additional, Caanen, Barbara A. H., additional, Stiggelbout, Anne M., additional, and Smets, Ellen M. A., additional

Published
2019
Full Text
View/download PDF

17. The development of an online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making: a usability and pilot study

Author

Reumkens, Kelly, primary, Tummers, Marly H. E., additional, Gietel-Habets, Joyce J. G., additional, van Kuijk, Sander M. J., additional, Aalfs, Cora M., additional, van Asperen, Christi J., additional, Ausems, Margreet G. E. M., additional, Collée, Margriet, additional, Dommering, Charlotte J., additional, Kets, C. Marleen, additional, van der Kolk, Lizet E., additional, Oosterwijk, Jan C., additional, Tjan-Heijnen, Vivianne C. G., additional, van der Weijden, Trudy, additional, de Die-Smulders, Christine E. M., additional, and van Osch, Liesbeth A. D. M., additional

Published
2018
Full Text
View/download PDF

21. Factors associated with cancer worries in individuals participating in annual pancreatic cancer surveillance.

Author

Konings IC, Harinck F, Kuenen MA, Sidharta GN, Kieffer JM, Aalfs CM, Poley JW, Smets EM, Wagner A, van Rens A, Vleggaar FP, Ausems MG, Fockens P, van Hooft JE, Bruno MJ, and Bleiker EM

Subjects
Adult, Aged, Anxiety, Carcinoma, Pancreatic Ductal surgery, Endosonography, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Pancreatic Neoplasms surgery, Surveys and Questionnaires, Carcinoma, Pancreatic Ductal diagnostic imaging, Carcinoma, Pancreatic Ductal psychology, Pancreatic Neoplasms diagnostic imaging, Pancreatic Neoplasms psychology
Abstract

It is important to adequately and timely identify individuals with cancer worries amongst participants in a pancreatic ductal adenocarcinoma (PDAC) surveillance program, because they could benefit from psychosocial support to decrease distress. Therefore, the aim of this study was to assess both psychosocial and clinical factors associated with cancer worries. High-risk individuals participating in PDAC-surveillance were invited to annually complete a cancer worry scale (CWS) questionnaire which was sent after counseling by the clinical geneticist (T0), after intake for participation in PDAC-surveillance (T1), and then annually after every MRI and endoscopic ultrasonography (EUS) (T2 and further). Analyses were performed to identify factors associated with cancer worries in the second year of surveillance (T3). We found a significant intra-individual decrease in cancer worries (β = -0.84, P < 0.001), nevertheless, 33 % of individuals had a CWS-score ≥14 at T3. We found one factor significantly associated with cancer worries at T3: having a family member affected by PDAC <50 years of age (β = 0.22, P = 0.03). The detection of a cystic lesion, a shortened surveillance interval, or undergoing pancreatic surgery did not lead to more cancer worries (P = 0.163, P = 0.33, and P = 0.53, respectively). In conclusion, this study identified 'a family history of PDAC <50 years of age' as the only predictor of cancer worries experienced after 2 years of surveillance in individuals at high risk of developing PDAC. This knowledge could help clinicians to timely identify individuals 'at risk' for high levels of cancer worries who would likely benefit from psychosocial support., Competing Interests: The authors declare that they have no conflict of interest. Ethical approval All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent Informed consent was obtained from all individual participants included in the study. Research involving human participants The Ethical Committee of all participating centers approved the study protocol and the study was conducted in accordance with the Declaration of Helsinki. All participants gave written informed consent prior to the performance of any study-related investigations.

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results