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Byline: D. J. Fixsen (1,2), R. H. Cornett (1) Keywords: array detectors; IR detectors; JWST; observationstrategies Abstract: The frequency at which a large space telescope's (e.g. JWST's) detector chips are read, or the sample rate, is tightly coupled to many hardware and operational aspects of the telescope's instrument and data handling elements. In this paper we discuss many of the drivers and important implications of the sample rate: the data rate to the ground onboard computer storage, bandwidth, and speed the number of A[right arrow]D chips, and therefore the overall size and power requirements of the analog electronics cryocabling requirements and detector noise and power. We discuss and parametrize these and other elements related to sample rate. Finally, we discuss the implications of sample rate in the context of achieving the most important science goals under the constraint of limited cost. Author Affiliation: (1) SSAI, Code 685, NASA/GSFC, Greenbelt, MD, U.S.A. (2) Code 685, NASA Goddard Space Flight Center, Greenbelt, MD, U.S.A. Article History: Registration Date: 12/10/2004