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MOUSA, UMUT/0000-0002-8078-9376 WOS: 000350789400007 PubMed: 25343266 Chronic complications are the leading causes of morbidity and mortality in the diabetic population. The intrarenal resistive index ( RI) has been reported to be increased in hypertensive subjects with microalbuminuria and limited data is present for diabetic subjects. 101 subjects with Type 2 Diabetes Mellitus were included in the study. We grouped the study population according to the urinary albumin excretion ( UAE). Group 1: UAE < 30 mg/ day ( n = 36); Group 2: UAE 30- 300 mg/ day ( n: 37); Group 3: UAE > 300 mg/ day ( n: 28). We also grouped the study population according to the intrarenal RI value. Group consisted of subjects with RI = 0.70 and group II < 0.70. The mean intrarenal RI values of patients in group 3 were higher than those of group 1 and group 2 ( 0.72 vs. 0.69 p = 0.048; 0.72 vs. 0.69; p = 0.048 respectively). The duration of diabetes, hip circumference, and hs- CRP levels were statistically significantly higher in subjects with intrarenal RI = 0.70 compared to those with intrarenal RI < 0.70 ( p: < 0.001, 0.048 and 0.0148 respectively). Presence of retinopathy and neuropathy was statistically significantly higher in subjects with intrarenal RI = 0.70 compared to those with intrarenal RI < 0.70. RI may predict the development of microvascularcomplications in diabetic subjects.

Although obesity is a powerful risk factor for metabolic syndrome (MetS) it is not present in all obese individuals. Increased visceral adipose tissue is the hallmark of this syndrome. In this cross sectional survey we aimed to use abdominal bioelectrical impedance analysis to measure the visceral adipose tissue (VAT) and trunk fat percentages (TF%) in the study population, correlate these findings with traditional anthropometric measures and biochemical parameters of metabolic syndrome and estimate a cut-off value of visceral fat for development of MetS. A total of 285 subjects were enrolled. VAT and TF% were measured by the AB-140 device via abdominal bioelectrical impedance analysis. Fat% was measured by a body composition analyzer (TBF-300). VAT was significantly positively correlated with body mass index, waist circumference, TF%, HOMA IR, fat percentage, fasting plasma glucose and triglycerides. Strongest correlations were between VAT and TF%, VAT and device measured waist circumference and between VAT and manual waist circumference (r=0.95, r=0.93, r=0.92 respectively). Correlations of VAT and TF% with metabolic parameters were significant but weak. The mean VAT and TF% in MetS (+) groups were significantly higher than patients in MetS (-) groups in both sexes. The areas under the ROC curves were 0.730 (95% CI: 0.661-0.791) for female VAT and 0.702 (95% CI: 0.654-0.749) for male VAT in predicting MetS which were similar to the areas under ROC curves calculated for device and manually measured waist circumference, HOMA IR and TF% in predicting MetS (p>0.05 for all comparisons). The accuracy of VAT and TF% for predicting MetS was not sufficient. From our results we can deduce that the performance of abdominal BIA in predicting MetS is weak but could be used in the follow-up of patients with obesity and/or MetS. This has to be confirmed in future studies.