1. Über eisenhaltige Wachstumsfaktoren, die Sideramine, und ihre Antagonisten, die eisenhaltigen Antibiotika Sideromycine
- Author
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Keller-Schierlein W, H. Bickel, Prelog, E. Vischer, Zaehner H, Gaeumann E, and Albert Wettstein
- Subjects
Pharmacology ,medicine.drug_class ,Chemistry ,Stereochemistry ,Microorganism ,Antibiotics ,Cell Biology ,Cellular and Molecular Neuroscience ,chemistry.chemical_compound ,Biochemistry ,Biological property ,medicine ,Molecular Medicine ,Molecular Biology ,Ferrichrome - Abstract
A new group of iron-containing metabolites, with growth stimulating properties for a number of microorganisms, has been isolated from streptomycetes and namedferrioxamines. It is proposed to include them, together with some known substances, like ferrichrome, coprogen and the terregens factor, which either contain or bind iron, in a new class of growth factors, thesideramines. The biological property of the sideramines is counteracted by iron-containing antibiotics from streptomycetes, thesideromycins. They comprise, besides known products like grisein and albomycin, two new groups of antibiotics, among them the highly potentferrimycins.
- Published
- 1960
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