1. Accounting for baseline differences in meta-analysis.
- Author
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Chaimani, Anna
- Subjects
- *
CONFIDENCE intervals , *PSYCHOTHERAPY patients , *RESEARCH funding , *STATISTICS , *DATA analysis , *SEVERITY of illness index , *ODDS ratio - Abstract
The article offers an overview of meta-regression models and possible assumptions that can be employed in mental health disorder trials to account for differences in baseline characteristics of participants between the studies of a meta-analysis. Two datasets of antidepressant trials including fluoxetine, venlafaxine, nefazodone and parosetine that applied the meta-regression models versus placebo are presented. The paper investigates the underlying risks for developing depression.
- Published
- 2015
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