1. An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021
- Author
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James Lopez Bernal, Shamez N Ladhani, Nalini Iyanger, Vanessa Saliba, Kelly Stoker, Sarah V Williams, Nick Andrews, Laurence John, Mary Ramsay, Amoolya Vusirikala, Felicity Aiano, Elena Fernandez Ruiz De Olano, B. Patel, Kevin E. Brown, Gavin Dabrera, and Guduru Gopal Rao
- Subjects
Delta ,Delta variant ,medicine.medical_specialty ,2019-20 coronavirus outbreak ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,Epidemiology ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Attack rate ,Vaxzevria ,ChAdOx1 vaccine ,030204 cardiovascular system & hematology ,Disease Outbreaks ,B.1.617.2 variant ,03 medical and health sciences ,0302 clinical medicine ,Virology ,London ,medicine ,Humans ,030212 general & internal medicine ,care home outbreaks ,vaccine effectiveness ,SARS-CoV-2 ,business.industry ,Vaccination ,Public Health, Environmental and Occupational Health ,COVID-19 ,Outbreak ,England ,Emergency medicine ,business ,Rapid Communication - Abstract
We investigated a COVID-19 outbreak of the SARS-CoV-2 Delta variant of concern in a London care home, where 8/21 residents and 14/21 staff had received a single dose of Vaxzevria (ChAdOx1-S; AstraZeneca) vaccine. We identified 24 SARS-CoV-2 infections (16 residents, 8 staff) among 40 individuals (19 residents, 21 staff); four (3 residents, 1 staff) were hospitalised, and none died. The attack rate after one vaccine dose was 35.7% (5/14) for staff and 81.3% (13/16) for residents.
- Published
- 2021
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