1. Do Seminal or Prostatic Secretions Play a Role in Local Recurrence after Radical Prostatectomy for Localized Prostate Cancer?
- Author
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A. Abi-Aad, Reinier-Jacques Opsomer, Francis Lorge, Henri Noël, Paul Van Cangh, and François-Xavier Wese
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Prostatic secretions ,Prostate cancer ,Neoplasm Seeding ,Seminal vesicle ,Prostate ,Cytology ,Humans ,Medicine ,Prostatectomy ,Pathologic stage ,business.industry ,Prostatic Neoplasms ,Seminal Vesicles ,Tumor Spillage ,medicine.disease ,Body Fluids ,medicine.anatomical_structure ,Neoplasm Recurrence, Local ,business - Abstract
Neoplastic cellular contamination of the surgical bed may be responsible for late local failure after radical prostatectomy. Cytology analysis of the seminal and prostatic fluid collected intraoperatively was undertaken in 30 patients. Neoplastic cells were found in 2 patients both with seminal vesicle involvement. Although it is difficult to admit that tumor spillage during surgery would be a major cause of local recurrence, the presence of tumor cells in the ejaculate may be diagnostic of seminal vesicle invasion. All patients with pathologic stage T2 had a negative cytologic finding.
- Published
- 1993
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