Search

Your search keyword '"Goletti Delia"' showing total 28 results
Start Over Author "Goletti Delia" Journal european respiratory journal
28 results on '"Goletti Delia"'

1. Rifapentine access in Europe: growing concerns over key tuberculosis treatment component

Author

Guglielmetti, Lorenzo, primary, Günther, Gunar, additional, Leu, Claude, additional, Cirillo, Daniela, additional, Duarte, Raquel, additional, Garcia-Basteiro, Alberto L., additional, Goletti, Delia, additional, Jankovic, Mateja, additional, Kuksa, Liga, additional, Maurer, Florian P., additional, Méchaï, Frédéric, additional, Tiberi, Simon, additional, van Leth, Frank, additional, Veziris, Nicolas, additional, and Lange, Christoph, additional

Published
2022
Full Text
View/download PDF

4. On tuberculosis and COVID-19 co-infection

Author

Tadolini, Marina, primary, García-García, José-María, additional, Blanc, François-Xavier, additional, Borisov, Sergey, additional, Goletti, Delia, additional, Motta, Ilaria, additional, Codecasa, Luigi Ruffo, additional, Tiberi, Simon, additional, Sotgiu, Giovanni, additional, and Migliori, Giovanni Battista, additional

Published
2020
Full Text
View/download PDF

5. Epidemic and pandemic viral infections: impact on tuberculosis and the lung

Author

Ong, Catherine Wei Min, primary, Migliori, Giovanni Battista, additional, Raviglione, Mario, additional, MacGregor-Skinner, Gavin, additional, Sotgiu, Giovanni, additional, Alffenaar, Jan-Willem, additional, Tiberi, Simon, additional, Adlhoch, Cornelia, additional, Alonzi, Tonino, additional, Archuleta, Sophia, additional, Brusin, Sergio, additional, Cambau, Emmanuelle, additional, Capobianchi, Maria Rosaria, additional, Castilletti, Concetta, additional, Centis, Rosella, additional, Cirillo, Daniela M., additional, D'Ambrosio, Lia, additional, Delogu, Giovanni, additional, Esposito, Susanna M.R., additional, Figueroa, Jose, additional, Friedland, Jon S., additional, Ho, Benjamin Choon Heng, additional, Ippolito, Giuseppe, additional, Jankovic, Mateja, additional, Kim, Hannah Yejin, additional, Rosales Klintz, Senia, additional, Ködmön, Csaba, additional, Lalle, Eleonora, additional, Leo, Yee Sin, additional, Leung, Chi-Chiu, additional, Märtson, Anne-Grete, additional, Melazzini, Mario Giovanni, additional, Najafi Fard, Saeid, additional, Penttinen, Pasi, additional, Petrone, Linda, additional, Petruccioli, Elisa, additional, Pontali, Emanuele, additional, Saderi, Laura, additional, Santin, Miguel, additional, Spanevello, Antonio, additional, van Crevel, Reinout, additional, van der Werf, Marieke J., additional, Visca, Dina, additional, Viveiros, Miguel, additional, Zellweger, Jean-Pierre, additional, Zumla, Alimuddin, additional, and Goletti, Delia, additional

Published
2020
Full Text
View/download PDF

6. Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases

Author

Tadolini, Marina, primary, Codecasa, Luigi Ruffo, additional, García-García, José-María, additional, Blanc, François-Xavier, additional, Borisov, Sergey, additional, Alffenaar, Jan-Willem, additional, Andréjak, Claire, additional, Bachez, Pierre, additional, Bart, Pierre-Alexandre, additional, Belilovski, Evgeny, additional, Cardoso-Landivar, José, additional, Centis, Rosella, additional, D'Ambrosio, Lia, additional, Luiza De Souza-Galvão, María-, additional, Dominguez-Castellano, Angel, additional, Dourmane, Samir, additional, Fréchet Jachym, Mathilde, additional, Froissart, Antoine, additional, Giacomet, Vania, additional, Goletti, Delia, additional, Grard, Soazic, additional, Gualano, Gina, additional, Izadifar, Armine, additional, Le Du, Damien, additional, Marín Royo, Margarita, additional, Mazza-Stalder, Jesica, additional, Motta, Ilaria, additional, Ong, Catherine Wei Min, additional, Palmieri, Fabrizio, additional, Rivière, Frédéric, additional, Rodrigo, Teresa, additional, Silva, Denise Rossato, additional, Sánchez-Montalvá, Adrián, additional, Saporiti, Matteo, additional, Scarpellini, Paolo, additional, Schlemmer, Frédéric, additional, Spanevello, Antonio, additional, Sumarokova, Elena, additional, Tabernero, Eva, additional, Tambyah, Paul Anantharajah, additional, Tiberi, Simon, additional, Torre, Alessandro, additional, Visca, Dina, additional, Zabaleta Murguiondo, Miguel, additional, Sotgiu, Giovanni, additional, and Migliori, Giovanni Battista, additional

Published
2020
Full Text
View/download PDF

10. An evaluation framework for new tests that predict progression from tuberculosis infection to clinical disease

Author

Kik, Sandra V., primary, Schumacher, Samuel, additional, Cirillo, Daniela Maria, additional, Churchyard, Gavin, additional, Boehme, Catharina, additional, Goletti, Delia, additional, Rangaka, Molebogeng X., additional, Denkinger, Claudia M., additional, Lienhardt, Christian, additional, Gilpin, Christopher, additional, Matteelli, Alberto, additional, and Cobelens, Frank, additional

Published
2018
Full Text
View/download PDF

11. Standard operating procedures for tuberculosis care

Author

Solovic, Ivan, primary, Abubakar, Ibrahim, additional, Sotgiu, Giovanni, additional, Dara, Masoud, additional, Goletti, Delia, additional, Duarte, Raquel, additional, Aliberti, Stefano, additional, de Benedictis, Fernando Maria, additional, Ward, Brian, additional, Teixeira, Vitor, additional, Gratziou, Christina, additional, and Migliori, Giovanni Battista, additional

Published
2017
Full Text
View/download PDF

12. Long-lasting tuberculous pleurisy

Author

Petruccioli, Elisa, primary, Scriba, Thomas J., additional, Petrone, Linda, additional, Hatherill, Mark, additional, Cirillo, Daniela M., additional, Joosten, Simone A., additional, Codecasa, Luigi R., additional, Ottenhoff, Tom H., additional, Denkinger, Claudia M., additional, and Goletti, Delia, additional

Published
2017
Full Text
View/download PDF

15. Tuberculosis care among refugees arriving in Europe: a ERS/WHO Europe Region survey of current practices

Author

Dara, Masoud, primary, Solovic, Ivan, additional, Sotgiu, Giovanni, additional, D'Ambrosio, Lia, additional, Centis, Rosella, additional, Tran, Richard, additional, Goletti, Delia, additional, Duarte, Raquel, additional, Aliberti, Stefano, additional, de Benedictis, Fernando Maria, additional, Bothamley, Graham, additional, Schaberg, Tom, additional, Abubakar, Ibrahim, additional, Teixeira, Vitor, additional, Ward, Brian, additional, Gratziou, Christina, additional, and Migliori, Giovanni Battista, additional

Published
2016
Full Text
View/download PDF

16. First evaluation of QuantiFERON-TB Gold Plus performance in contact screening

Author

Barcellini, Lucia, primary, Borroni, Emanuele, additional, Brown, James, additional, Brunetti, Enrico, additional, Campisi, Daniela, additional, Castellotti, Paola F., additional, Codecasa, Luigi R., additional, Cugnata, Federica, additional, Di Serio, Clelia, additional, Ferrarese, Maurizio, additional, Goletti, Delia, additional, Lipman, Marc, additional, Rancoita, Paola M.V., additional, Russo, Giulia, additional, Tadolini, Marina, additional, Vanino, Elisa, additional, and Cirillo, Daniela M., additional

Published
2016
Full Text
View/download PDF

18. Call for urgent actions to ensure access to early diagnosis and care of tuberculosis among refugees

Author

Dara, Masoud, primary, Solovic, Ivan, additional, Sotgiu, Giovanni, additional, D'Ambrosio, Lia, additional, Centis, Rosella, additional, Goletti, Delia, additional, Duarte, Raquel, additional, Aliberti, Stefano, additional, de Benedictis, Fernando Maria, additional, Bothamley, Graham, additional, Schaberg, Tom, additional, Abubakar, Ibrahim, additional, Ward, Brian, additional, Teixeira, Vitor, additional, Gratziou, Christina, additional, and Migliori, Giovanni Battista, additional

Published
2016
Full Text
View/download PDF

19. First independent evaluation of QuantiFERON-TB Plus performance

Author

Barcellini, Lucia, primary, Borroni, Emanuele, additional, Brown, James, additional, Brunetti, Enrico, additional, Codecasa, Luigi, additional, Cugnata, Federica, additional, Dal Monte, Paola, additional, Di Serio, Clelia, additional, Goletti, Delia, additional, Lombardi, Giulia, additional, Lipman, Marc, additional, Rancoita, Paola M.V., additional, Tadolini, Marina, additional, and Cirillo, Daniela M., additional

Published
2016
Full Text
View/download PDF

21. Towards tuberculosis elimination: an action framework for low-incidence countries

Author

Lönnroth, Knut, primary, Migliori, Giovanni Battista, additional, Abubakar, Ibrahim, additional, D'Ambrosio, Lia, additional, de Vries, Gerard, additional, Diel, Roland, additional, Douglas, Paul, additional, Falzon, Dennis, additional, Gaudreau, Marc-Andre, additional, Goletti, Delia, additional, González Ochoa, Edilberto R., additional, LoBue, Philip, additional, Matteelli, Alberto, additional, Njoo, Howard, additional, Solovic, Ivan, additional, Story, Alistair, additional, Tayeb, Tamara, additional, van der Werf, Marieke J., additional, Weil, Diana, additional, Zellweger, Jean-Pierre, additional, Abdel Aziz, Mohamed, additional, Al Lawati, Mohamed R.M., additional, Aliberti, Stefano, additional, Arrazola de Oñate, Wouter, additional, Barreira, Draurio, additional, Bhatia, Vineet, additional, Blasi, Francesco, additional, Bloom, Amy, additional, Bruchfeld, Judith, additional, Castelli, Francesco, additional, Centis, Rosella, additional, Chemtob, Daniel, additional, Cirillo, Daniela M., additional, Colorado, Alberto, additional, Dadu, Andrei, additional, Dahle, Ulf R., additional, De Paoli, Laura, additional, Dias, Hannah M., additional, Duarte, Raquel, additional, Fattorini, Lanfranco, additional, Gaga, Mina, additional, Getahun, Haileyesus, additional, Glaziou, Philippe, additional, Goguadze, Lasha, additional, del Granado, Mirtha, additional, Haas, Walter, additional, Järvinen, Asko, additional, Kwon, Geun-Yong, additional, Mosca, Davide, additional, Nahid, Payam, additional, Nishikiori, Nobuyuki, additional, Noguer, Isabel, additional, O'Donnell, Joan, additional, Pace-Asciak, Analita, additional, Pompa, Maria G., additional, Popescu, Gilda G., additional, Robalo Cordeiro, Carlos, additional, Rønning, Karin, additional, Ruhwald, Morten, additional, Sculier, Jean-Paul, additional, Simunović, Aleksandar, additional, Smith-Palmer, Alison, additional, Sotgiu, Giovanni, additional, Sulis, Giorgia, additional, Torres-Duque, Carlos A., additional, Umeki, Kazunori, additional, Uplekar, Mukund, additional, van Weezenbeek, Catharina, additional, Vasankari, Tuula, additional, Vitillo, Robert J., additional, Voniatis, Constantia, additional, Wanlin, Maryse, additional, and Raviglione, Mario C., additional

Published
2015
Full Text
View/download PDF

22. False-negative interferon-γ release assay results in active tuberculosis: a TBNET study

Author

de Visser, Veerle, primary, Sotgiu, Giovanni, additional, Lange, Christoph, additional, Aabye, Martine G., additional, Bakker, Marleen, additional, Bartalesi, Filippo, additional, Brat, Kristian, additional, Chee, Cynthia B.E., additional, Dheda, Keertan, additional, Dominguez, Jose, additional, Eyuboglu, Fusun, additional, Ghanem, Maha, additional, Goletti, Delia, additional, Dilektasli, Asli Gorek, additional, Guglielmetti, Lorenzo, additional, Koh, Won-Jung, additional, Latorre, Irene, additional, Losi, Monica, additional, Polanova, Monica, additional, Ravn, Pernille, additional, Ringshausen, Felix C., additional, Rumetshofer, Rudolf, additional, de Souza-Galvão, Maria Luiza, additional, Thijsen, Steven, additional, Bothamley, Graham, additional, and Bossink, Aik, additional

Published
2014
Full Text
View/download PDF

23. The risk of tuberculosis in transplant candidates and recipients: a TBNET consensus statement

Author

Bumbacea, Dragos, primary, Arend, Sandra M., additional, Eyuboglu, Fusun, additional, Fishman, Jay A., additional, Goletti, Delia, additional, Ison, Michael G., additional, Jones, Christine E., additional, Kampmann, Beate, additional, Kotton, Camille N., additional, Lange, Christoph, additional, Ljungman, Per, additional, Milburn, Heather, additional, Morris, Michele I., additional, Muller, Elmi, additional, Muñoz, Patricia, additional, Nellore, Anoma, additional, Rieder, Hans L., additional, Sester, Urban, additional, Theodoropoulos, Nicole, additional, Wagner, Dirk, additional, and Sester, Martina, additional

Published
2012
Full Text
View/download PDF

24. On tuberculosis and COVID-19 co-infection

Author

Simon Tiberi, Delia Goletti, Sergey Borisov, Marina Tadolini, François-Xavier Blanc, José-María García-García, Luigi Codecasa, Ilaria Motta, Giovanni Sotgiu, Giovanni Battista Migliori, Tadolini, Marina, García-García, José-María, Blanc, François-Xavier, Borisov, Sergey, Goletti, Delia, Motta, Ilaria, Codecasa, Luigi Ruffo, Tiberi, Simon, Sotgiu, Giovanni, and Migliori, Giovanni Battista

Subjects
Pulmonary and Respiratory Medicine, 2019-20 coronavirus outbreak, Tuberculosis, Coronavirus disease 2019 (COVID-19), Pneumonia, Viral, 03 medical and health sciences, 0302 clinical medicine, Pandemic, Medicine, 030212 general & internal medicine, Betacoronaviru, SARS-CoV-2, Coinfection, Coronavirus Infection, business.industry, COVID-19, medicine.disease, Virology, Pneumonia, 030228 respiratory system, business, Coronavirus Infections, Human, Co infection
Abstract

COVID-19 may boost tuberculosis given infection and mortality, further studies are needed https://bit.ly/2Z2r5XO

Published
2020

25. Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort.

Author

Casco N, Jorge AL, Palmero DJ, Alffenaar JW, Fox GJ, Ezz W, Cho JG, Denholm J, Skrahina A, Solodovnikova V, Arbex MA, Alves T, Rabahi MF, Pereira GR, Sales R, Silva DR, Saffie MM, Salinas NE, Miranda RC, Cisterna C, Concha C, Fernandez I, Villalón C, Vera CG, Tapia PG, Cancino V, Carbonell M, Cruz A, Muñoz E, Muñoz C, Navarro I, Pizarro R, Cristina Sánchez GP, Vergara Riquelme MS, Vilca E, Soto A, Flores X, Garavagno A, Bahamondes MH, Merino LM, Pradenas AM, Revillot ME, Rodriguez P, Salinas AS, Taiba C, Valdés JF, Subiabre JN, Ortega C, Palma S, Castillo PP, Pinto M, Bidegain FR, Venegas M, Yucra E, Li Y, Cruz A, Guelvez B, Victoria Plaza R, Tello Hoyos KY, Cardoso-Landivar J, Van Den Boom M, Andréjak C, Blanc FX, Dourmane S, Froissart A, Izadifar A, Rivière F, Schlemmer F, Manika K, Diallo BD, Hassane-Harouna S, Artiles N, Mejia LA, Gupta N, Ish P, Mishra G, Patel JM, Singla R, Udwadia ZF, Alladio F, Angeli F, Calcagno A, Centis R, Codecasa LR, De Lauretis A, Esposito SMR, Formenti B, Gaviraghi A, Giacomet V, Goletti D, Gualano G, Matteelli A, Migliori GB, Motta I, Palmieri F, Pontali E, Prestileo T, Riccardi N, Saderi L, Saporiti M, Sotgiu G, Spanevello A, Stochino C, Tadolini M, Torre A, Villa S, Visca D, Kurhasani X, Furjani M, Rasheed N, Danila E, Diktanas S, Ridaura RL, Luna López FL, Torrico MM, Rendon A, Akkerman OW, Chizaram O, Al-Abri S, Alyaquobi F, Althohli K, Aguirre S, Teixeira RC, De Egea V, Irala S, Medina A, Sequera G, Sosa N, Vázquez F, Llanos-Tejada FK, Manga S, Villanueva-Villegas R, Araujo D, Sales Marques RD, Socaci A, Barkanova O, Bogorodskaya M, Borisov S, Mariandyshev A, Kaluzhenina A, Vukicevic TA, Stosic M, Beh D, Ng D, Ong CWM, Solovic I, Dheda K, Gina P, Caminero JA, De Souza Galvão ML, Dominguez-Castellano A, García-García JM, Pinargote IM, Fernandez SQ, Sánchez-Montalvá A, Huguet ET, Murguiondo MZ, Bart PA, Mazza-Stalder J, D'Ambrosio L, Kamolwat P, Bakko F, Barnacle J, Bird S, Brown A, Chandran S, Killington K, Man K, Papineni P, Ritchie F, Tiberi S, Utjesanovic N, Zenner D, Hearn JL, Heysell S, and Young L

Subjects
Humans, Male, Risk Factors, Retrospective Studies, COVID-19 complications, HIV Infections complications, Coinfection, Tuberculosis, Miliary
Abstract

Background: Longitudinal cohort data of patients with tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are lacking. In our global study, we describe long-term outcomes of patients affected by TB and COVID-19., Methods: We collected data from 174 centres in 31 countries on all patients affected by COVID-19 and TB between 1 March 2020 and 30 September 2022. Patients were followed-up until cure, death or end of cohort time. All patients had TB and COVID-19; for analysis purposes, deaths were attributed to TB, COVID-19 or both. Survival analysis was performed using Cox proportional risk-regression models, and the log-rank test was used to compare survival and mortality attributed to TB, COVID-19 or both., Results: Overall, 788 patients with COVID-19 and TB (active or sequelae) were recruited from 31 countries, and 10.8% (n=85) died during the observation period. Survival was significantly lower among patients whose death was attributed to TB and COVID-19 versus those dying because of either TB or COVID-19 alone (p<0.001). Significant adjusted risk factors for TB mortality were higher age (hazard ratio (HR) 1.05, 95% CI 1.03-1.07), HIV infection (HR 2.29, 95% CI 1.02-5.16) and invasive ventilation (HR 4.28, 95% CI 2.34-7.83). For COVID-19 mortality, the adjusted risks were higher age (HR 1.03, 95% CI 1.02-1.04), male sex (HR 2.21, 95% CI 1.24-3.91), oxygen requirement (HR 7.93, 95% CI 3.44-18.26) and invasive ventilation (HR 2.19, 95% CI 1.36-3.53)., Conclusions: In our global cohort, death was the outcome in >10% of patients with TB and COVID-19. A range of demographic and clinical predictors are associated with adverse outcomes., Competing Interests: Conflict of interest: The authors have no potential conflicts of interest to disclose., (Copyright ©The authors 2023.)

Published
2023
Full Text
View/download PDF

26. Gauging the impact of the COVID-19 pandemic on tuberculosis services: a global study.

Author

Migliori GB, Thong PM, Alffenaar JW, Denholm J, Tadolini M, Alyaquobi F, Blanc FX, Buonsenso D, Cho JG, Codecasa LR, Danila E, Duarte R, García-García JM, Gualano G, Rendon A, Silva DR, Souleymane MB, Tham SM, Thomas TA, Tiberi S, Udwadia ZF, Goletti D, Centis R, D'Ambrosio L, Sotgiu G, and Ong CWM

Subjects
Humans, Pandemics, SARS-CoV-2, COVID-19, Tuberculosis epidemiology, Tuberculosis therapy
Abstract

Competing Interests: Conflict of interest: G.B. Migliori has nothing to disclose. Conflict of interest: P.M. Thong has nothing to disclose. Conflict of interest: J-W. Alffenaar has nothing to disclose. Conflict of interest: J. Denholm has nothing to disclose. Conflict of interest: M. Tadolini has nothing to disclose. Conflict of interest: F. Alyaquobi has nothing to disclose. Conflict of interest: F-X. Blanc has nothing to disclose. Conflict of interest: D. Buonsenso has nothing to disclose. Conflict of interest: J-G. Cho has nothing to disclose. Conflict of interest: L.R. Codecasa has nothing to disclose. Conflict of interest: E. Danila has nothing to disclose. Conflict of interest: R. Duarte has nothing to disclose. Conflict of interest: J-M. García-García has nothing to disclose. Conflict of interest: G. Gualano has nothing to disclose. Conflict of interest: A. Rendon has nothing to disclose. Conflict of interest: D.R. Silva has nothing to disclose. Conflict of interest: M.B. Souleymane has nothing to disclose. Conflict of interest: S.M. Tham has nothing to disclose. Conflict of interest: T.A. Thomas has nothing to disclose. Conflict of interest: S. Tiberi has nothing to disclose. Conflict of interest: Z.F. Udwadia has nothing to disclose. Conflict of interest: D. Goletti has nothing to disclose. Conflict of interest: R. Centis has nothing to disclose. Conflict of interest: L. D'Ambrosio has nothing to disclose. Conflict of interest: G. Sotgiu has nothing to disclose. Conflict of interest: C.W.M. Ong reports grants from National Medical Research Council (CSAINV17nov014), personal fees (young investigator award) from Institut Merieux, during the conduct of the study; other (honorarium) from Qiagen, outside the submitted work.

Published
2021
Full Text
View/download PDF

27. False-negative interferon-γ release assay results in active tuberculosis: a TBNET study.

Author

de Visser V, Sotgiu G, Lange C, Aabye MG, Bakker M, Bartalesi F, Brat K, Chee CB, Dheda K, Dominguez J, Eyuboglu F, Ghanem M, Goletti D, Dilektasli AG, Guglielmetti L, Koh WJ, Latorre I, Losi M, Polanova M, Ravn P, Ringshausen FC, Rumetshofer R, de Souza-Galvão ML, Thijsen S, Bothamley G, and Bossink A

Subjects
Adult, Cross-Sectional Studies, Female, Genetic Variation, Humans, International Cooperation, Logistic Models, Male, Middle Aged, Multivariate Analysis, Regression Analysis, Retrospective Studies, Risk Factors, Surveys and Questionnaires, False Negative Reactions, Interferon-gamma metabolism, Interferon-gamma Release Tests methods, Tuberculosis diagnosis
Published
2015
Full Text
View/download PDF

28. Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement.

Author

Lange C, Abubakar I, Alffenaar JW, Bothamley G, Caminero JA, Carvalho AC, Chang KC, Codecasa L, Correia A, Crudu V, Davies P, Dedicoat M, Drobniewski F, Duarte R, Ehlers C, Erkens C, Goletti D, Günther G, Ibraim E, Kampmann B, Kuksa L, de Lange W, van Leth F, van Lunzen J, Matteelli A, Menzies D, Monedero I, Richter E, Rüsch-Gerdes S, Sandgren A, Scardigli A, Skrahina A, Tortoli E, Volchenkov G, Wagner D, van der Werf MJ, Williams B, Yew WW, Zellweger JP, and Cirillo DM

Subjects
Case Management, Clinical Trials as Topic, Communicable Disease Control, Consensus, Disease Management, Disease-Free Survival, Europe, Extensively Drug-Resistant Tuberculosis epidemiology, Extensively Drug-Resistant Tuberculosis prevention & control, Geography, Humans, Infectious Disease Medicine standards, Public Health, Recurrence, Treatment Outcome, Tuberculosis, Multidrug-Resistant epidemiology, Tuberculosis, Multidrug-Resistant prevention & control, World Health Organization, Antitubercular Agents therapeutic use, Extensively Drug-Resistant Tuberculosis therapy, Tuberculosis, Multidrug-Resistant therapy
Abstract

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) substantially challenges TB control, especially in the European Region of the World Health Organization, where the highest prevalence of MDR/XDR cases is reported. The current management of patients with MDR/XDR-TB is extremely complex for medical, social and public health systems. The treatment with currently available anti-TB therapies to achieve relapse-free cure is long and undermined by a high frequency of adverse drug events, suboptimal treatment adherence, high costs and low treatment success rates. Availability of optimal management for patients with MDR/XDR-TB is limited even in the European Region. In the absence of a preventive vaccine, more effective diagnostic tools and novel therapeutic interventions the control of MDR/XDR-TB will be extremely difficult. Despite recent scientific advances in MDR/XDR-TB care, decisions for the management of patients with MDR/XDR-TB and their contacts often rely on expert opinions, rather than on clinical evidence. This document summarises the current knowledge on the prevention, diagnosis and treatment of adults and children with MDR/XDR-TB and their contacts, and provides expert consensus recommendations on questions where scientific evidence is still lacking., (©ERS 2014.)

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results