6 results on '"Cheng, Yu-Chen"'
Search Results
2. Changes in sensorimotor-related thalamic diffusion properties and cerebrospinal fluid hydrodynamics predict gait responses to tap test in idiopathic normal-pressure hydrocephalus
- Author
-
Yung Chieh Chen, Hsiao Wen Chung, Giia Sheun Peng, Hua Shan Liu, Teng-Yi Huang, Shih Wei Chiang, Hung Wen Kao, Ping Huei Tsai, Hsin I. Ma, Cheng Yu Chen, and Ming Chung Chou
- Subjects
Male ,medicine.medical_specialty ,Sensitivity and Specificity ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Cerebrospinal fluid ,Gait (human) ,Thalamus ,Internal medicine ,Fractional anisotropy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Gait ,Aged ,Cerebrospinal Fluid ,medicine.diagnostic_test ,Receiver operating characteristic ,business.industry ,Gait Disturbance ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Magnetic Resonance Imaging ,Hydrocephalus, Normal Pressure ,Diffusion Magnetic Resonance Imaging ,Diffusion Tensor Imaging ,ROC Curve ,Case-Control Studies ,Cardiology ,Mann–Whitney U test ,Hydrodynamics ,Anisotropy ,Female ,Radiology ,business ,030217 neurology & neurosurgery ,Diffusion MRI - Abstract
To compare diffusion tensor (DT)-derived indices from the thalamic nuclei and cerebrospinal fluid (CSF) hydrodynamic parameters for the prediction of gait responsiveness to the CSF tap test in early iNPH patients. In this study, 22 patients with iNPH and 16 normal controls were enrolled with the approval of an institutional review board. DT imaging and phase-contrast magnetic resonance imaging were performed in patients and controls to determine DT-related indices of the sensorimotor-related thalamic nuclei and CSF hydrodynamics. Gait performance was assessed in patients using gait scale before and after the tap test. The Mann-Whitney U test and receiver operating characteristic (ROC) curve analysis were applied to compare group differences between patients and controls and assess the predictive performance of gait responsiveness to the tap test in the patients. Fractional anisotropy (FA) and axial diffusivity showed significant increases in the ventrolateral (VL) and ventroposterolateral (VPL) nuclei of the iNPH group compared with those of the control group (p < 0.05). The predictions of gait responsiveness of ventral thalamic FA alone (area under the ROC curve [AUC] < 0.8) significantly outperformed those of CSF hydrodynamics alone (AUC < 0.6). The AUC curve was elevated to 0.812 when the CSF peak systolic velocity and FA value were combined for the VPL nucleus, yielding the highest sensitivity (0.769) and specificity (0.778) to predict gait responses. Combined measurements of sensorimotor-related thalamic FA and CSF hydrodynamics can provide potential biomarkers for gait response to the CSF tap test in patients with iNPH. • Ventrolateral and ventroposterolateral thalamic FA may predict gait responsiveness to tap test. • Thalamic neuroplasticity can be assessed through DTI in idiopathic normal-pressure hydrocephalus. • Changes in the CST associated with gait control could trigger thalamic neuroplasticity. • Activities of sensorimotor-related circuits could alter in patients with gait disturbance. • Management of patients with iNPH could be more appropriate.
- Published
- 2017
3. Neonatal neurological disorders involving the brainstem: neurosonographic approaches through the squamous suture and the foramen magnum
- Author
-
Yuh Jey Lin, Ying Chao Chang, Chao Ching Huang, Yi Fang Tu, and Cheng Yu Chen
- Subjects
Pathology ,medicine.medical_specialty ,Birth trauma ,Critical Illness ,Encephalopathy ,Hypoxic Ischemic Encephalopathy ,Parietal Bone ,Maple Syrup Urine Disease ,Meningoencephalitis ,Pons ,Streptococcal Infections ,Birth Injuries ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Foramen Magnum ,Encephalocele ,Ultrasonography ,Neuroradiology ,Brain Diseases ,Medulla Oblongata ,Foramen magnum ,medicine.diagnostic_test ,Brain Diseases, Metabolic ,business.industry ,Infant, Newborn ,Temporal Bone ,Magnetic resonance imaging ,Cranial Sutures ,General Medicine ,medicine.disease ,Magnetic Resonance Imaging ,Temporal Lobe ,medicine.anatomical_structure ,Hypoxia-Ischemia, Brain ,Feasibility Studies ,Radiology ,Brainstem ,Tomography, X-Ray Computed ,business ,Metabolism, Inborn Errors ,Brain Stem - Abstract
Brainstem damage which often indicates a critical condition is usually underestimated by trans-anterior-fontanel neurosonography (NS) owing to the far-field limitations. Instead, NS alternately scanning through the squamous suture of the temporal bones and the foramen magnum could provide a better visualization of the brainstem structures. The NS characteristics of brainstem lesions caused by various neonatal neurological disorders, such as hypoxic-ischemic encephalopathy (HIE), metabolic encephalopathy, birth trauma and bacterial meningoencephalitis, can be depicted at the acute stage. An echogenic change in the midbrain was found in patients with HIE or metabolic encephalopathy. In addition to the echogenic change, bilateral transtentorial temporal lobe herniation distorting the contour of the midbrain was observed in a patient with group B streptococcus meningoencephalitis, whereas echogenic changes at the level of the pons and/or the medulla oblongata, mainly localized in the dorsal part, could be observed in newborns with severe HIE, maple syrup urine disease or birth trauma. In this pictorial assay, we demonstrate the feasibility of NS imaging in evaluating the entire brainstem structure of critically ill neonates in the near field and illustrate the characteristic features of brainstem involvement in various neonatal neurological disorders along with computed tomography or magnetic resonance imaging correlation.
- Published
- 2005
4. A meniscus causing painful snapping of the elbow joint: MR imaging with arthroscopic and histologic correlation
- Author
-
Cheng Yu Chen, Guo-Shu Huang, Herng Sheng Lee, and Chian Her Lee
- Subjects
Adult ,Joint Instability ,Male ,musculoskeletal diseases ,medicine.medical_specialty ,Statistics as Topic ,Elbow ,Knee Joint ,Meniscus (anatomy) ,Arthroscopy ,Elbow Joint ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Arthrography ,medicine.diagnostic_test ,business.industry ,Synovial Membrane ,Ultrasound ,Fibrocartilage ,Magnetic resonance imaging ,General Medicine ,Anatomy ,musculoskeletal system ,Arthralgia ,Magnetic Resonance Imaging ,body regions ,Sound ,medicine.anatomical_structure ,Arthrogram ,Radiology ,business ,Cartilage Diseases - Abstract
Snapping of the elbow joint can cause pain. We report a case of painful snapping elbow produced by an interposed meniscus in the radiohumeral joint in a 20-year-old man. The MR arthrogram demonstrated a meniscus-like tissue interposed between the radial head and humeral capitellum. The MR-arthrographic findings were well correlated with surgical findings. The location and appearance of the meniscus-like tissue was similar to that of meniscus in the knee joint. Histologic findings of the excised meniscus-like tissue showed a typical presentation of fibrocartilage. A meniscus may exist in the elbow joint and can be a rare cause of painful snapping elbow. MR arthrography is helpful for identifying the snapping tissue in the elbow joint.
- Published
- 2005
5. Perfusion characteristics of late radiation injury of parotid glands: quantitative evaluation with dynamic contrast-enhanced MRI
- Author
-
Chao Ying Wang, Hsiao Wen Chung, Cheng Yu Chen, Chun-Jung Juan, Hua Shan Liu, Yi-Jui Liu, Guo-Shu Huang, Yee Min Jen, Yu Ching Chou, Yao Te Chai, and Chun Jen Hsueh
- Subjects
Adult ,Gadolinium DTPA ,Male ,medicine.medical_treatment ,Contrast Media ,Sensitivity and Specificity ,Xerostomia ,Young Adult ,stomatognathic system ,medicine ,Extracellular ,Humans ,Parotid Gland ,Radiology, Nuclear Medicine and imaging ,Radiation Injuries ,Neuroradiology ,Aged ,medicine.diagnostic_test ,business.industry ,Ultrasound ,Reproducibility of Results ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Magnetic Resonance Imaging ,Parotid gland ,Radiation therapy ,Radiography ,medicine.anatomical_structure ,Head and Neck Neoplasms ,Dynamic contrast-enhanced MRI ,Female ,business ,Nuclear medicine ,Perfusion - Abstract
We aimed to quantitatively investigate the alteration of parotid perfusion after irradiation using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on a two-compartment tracer kinetic model. This study enrolled 19 patients (53.2 +/- 14.9 years) treated by head and neck radiotherapy and 19 age-relevant and sex-matched subjects as a control group. Perfusion parameters (K ( el ), k (21) and A) of parotid glands were analyzed based on the Brix model from T1-weighted DCE-MRI. Suitability of the Brix model was evaluated via Monte Carlo simulation for the goodness-of-fit. Analysis of nonlinear goodness-of-fit showed that the Brix model is appropriate in evaluating the parotid perfusion (R(2) = 0.938 +/- 0.050). The irradiated parotid glands showed significantly lower K ( el ) (P0.0005) and k (21) (P0.05) and consequently significantly higher value of peak enhancement (P0.0005) and time-to-peak (P0.0005) compared with non-irradiated ones, suggestive of gradual and prolonged accumulation and delayed wash-out of contrast agent due to increased extracellular extravascular space and decreased vascular permeability in the irradiated glands. Linear regression analysis showed dose-dependent perfusion changes of the irradiated parotid glands. We conclude that quantitative DCE-MRI is a potential tool in investigating parotid gland perfusion changes after radiotherapy.
- Published
- 2007
6. A meniscus causing painful snapping of the elbow joint: MR imaging with arthroscopic and histologic correlation.
- Author
-
Guo-Shu Huang, Chian-Her Lee, Herng-Sheng Lee, and Cheng-Yu Chen
- Subjects
ELBOW ,JOINTS (Anatomy) ,MENISCUS (Anatomy) ,MAGNETIC resonance imaging ,DIAGNOSTIC imaging - Abstract
Snapping of the elbow joint can cause pain. We report a case of painful snapping elbow produced by an interposed meniscus in the radiohumeral joint in a 20-year-old man. The MR arthrogram demonstrated a meniscus-like tissue interposed between the radial head and humeral capitellum. The MR-arthrographic findings were well correlated with surgical findings. The location and appearance of the meniscus-like tissue was similar to that of meniscus in the knee joint. Histologic findings of the excised meniscus-like tissue showed a typical presentation of fibrocartilage. A meniscus may exist in the elbow joint and can be a rare cause of painful snapping elbow. MR arthrography is helpful for identifying the snapping tissue in the elbow joint. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.