Search

Your search keyword '"Malzeme Bilimi"' showing total 2 results
Start Over Descriptor "Malzeme Bilimi" Journal european polymer journal
2 results on '"Malzeme Bilimi"'

1. In vitro electrically controlled amoxicillin release from 3D-printed chitosan/bismuth ferrite scaffolds

Author

Dilruba Baykara, Esra Pilavci, Songul Ulag, Oseweuba Valentine Okoro, Lei Nie, Amin Shavandi, Ayse Ceren Koyuncu, Ozlem Bingol Ozakpinar, Mehmet Eroglu, Oguzhan Gunduz, and Baykara D., Pilavci E., Ulag S., Okoro O. V., Nie L., Shavandi A., Çalıkoğlu Koyuncu A. C., Ozakpinar O. B., Eroglu M., Gunduz O.

Subjects
Chitosan, Polymers and Plastics, Organic Chemistry, Amoxicillin, General Physics and Astronomy, Material science and engineering, Mühendislik, Bilişim ve Teknoloji (ENG), METALLURGY & METALLURGICAL ENGINEERING, 3D printing, Malzeme Bilimi ve Mühendisliği, Metallurgical and Materials Engineering, MATERIALS SCIENCE, Scaffold, Metalurji ve Malzeme Mühendisliği, Bismuth ferrite, Materials Chemistry, Engineering and Technology, Mühendislik ve Teknoloji, METALURJİ VE METALURJİ MÜHENDİSLİĞİ, Engineering, Computing & Technology (ENG), Malzeme Bilimi, Controlled drug delivery
Abstract

The goal of this study was to design and fabricate a 3D-printed wound dressing using chitosan as a bioink, with the ability to release the antibiotic drug amoxicillin (AMX) in response to mild electrical stimulation. This was achieved through the incorporation of bismuth ferrite (BFO) nanoparticles, which have both magnetic and ferroelectric properties. The chitosan-based scaffolds containing various concentrations of BFO were analyzed using Fourier transform infrared spectroscopy, and the release of AMX from the scaffolds was evaluated in vitro under electrical stimulation. The results demonstrated that the scaffolds had a suitable structure for drug loading and release, and the release of AMX was successfully controlled by the applied electrical stimulus. The maximum tensile strength (4.97 ± 0.34 MPa) was observed at the ratio of 6% CHT/0.025% BFO scaffolds and the scaffold with 6% CHT/0.075% BFO had the maximum cell viability of (~130%) at 168 h incubation time. This study highlights the potential of BFO to deliver therapeutic drugs from a 3D-printed chitosan scaffold in a controlled manner.

Published
2023
Full Text
View/download PDF

2. Development of self-healing vanillin/PEI hydrogels for tissue engineering

Author

Merve Yasar, Burcu Oktay, Fulya Dal Yontem, Ebru Haciosmanoglu Aldogan, Nilhan Kayaman Apohan, and Yasar M., OKTAY B., Dal Yontem F., Haciosmanoglu Aldogan E., KAYAMAN APOHAN N.

Subjects
Characterization of Polymers, Polymers and Plastics, Uzay bilimi, Temel Bilimler (SCI), Self-healing, General Physics and Astronomy, POLYMER SCIENCE, MATERIALS SCIENCE, MULTIDISCIPLINARY, Astronomi ve Astrofizik, Fizik, Biochemistry, Physical Chemistry, MATERIALS SCIENCE, Organik Kimya, Kimya, Polimerler ve Plastikler, CHEMISTRY, KİMYA, ORGANİK, ASTRONOMİ VE ASTROFİZİK, Biyokimya, Materials Chemistry, UV-polymerization, Biyoinorganik Kimya, ASTRONOMY & ASTROPHYSICS, MALZEME BİLİMİ, ÇOKDİSİPLİNLİ, Engineering, Computing & Technology (ENG), SPACE SCIENCE, Bioinorganic Chemistry, Malzeme Kimyası, Temel Bilimler, Physics, Polimer Karakterizasyonu, Organic Chemistry, Fizikokimya, Astronomy and Astrophysics, Mühendislik, Bilişim ve Teknoloji (ENG), Hydrogels, CHEMISTRY, ORGANIC, Genel Fizik ve Astronomi, Fizik Bilimleri, POLİMER BİLİMİ, Natural Sciences (SCI), Physical Sciences, Vanillin, Engineering and Technology, Mühendislik ve Teknoloji, Natural Sciences, Malzeme Bilimi
Abstract

Self-healing materials recover mechanical damages to expand the lifetime of the material provided. In this study, self-healing hydrogels have been successfully prepared using a novel and simple technique. Vanillin is a natural monomer, used as a bio-based cross-linker for UV-induced bonding and Schiff-base bonding. Methacrylate-functionalized vanillin (M-VAN) is covalently integrated with the polymer matrix. While M-VAN supports polymer matrix with its vinyl group, its aldehyde functionality helps the formation of dynamic covalent imine bonds via Schiff-base formation. The hydrogel showed excellent self-healing ability overnight under physiological conditions without external addition. In addition, the hydrogel surface was modified by collagen and its cell viability was investigated. The prepared scaffolds showed good cell viability of 124% and 163% compared to the control sample. The developed self-healing material reveals that it has possible uses for future biomedical applications and tissue engineering studies due to the self-healing mechanism taking place under ambient conditions.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results