1. 18F-FDG PET/CT in the evaluation of POEMS syndrome.
- Author
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Albertí MA, Martinez-Yélamos S, Fernandez A, Vidaller A, Narváez JA, Cano LM, Gamez C, and Martinez-Matos JA
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, Radiopharmaceuticals, Reproducibility of Results, Sensitivity and Specificity, Whole Body Imaging methods, Fluorodeoxyglucose F18, POEMS Syndrome diagnosis, Paraneoplastic Syndromes diagnosis, Positron-Emission Tomography methods, Subtraction Technique, Tomography, X-Ray Computed methods
- Abstract
In POEMS syndrome the identification and biopsy of an osteosclerotic lesion or a lymph node typical of Castleman's disease (CD) is essential to establish the diagnosis and plan appropriate treatment. We report four patients in whom the localisation and identification of diagnostic bone lesions or lymphadenopathies were guided by fluorodeoxyglucose positron emission tomography integrated with computerised tomography (FDG PET/CT). FDG PET/CT identified bone lesions not detected with other techniques in one patient, and revealed hypermetabolic characteristics in bone lesions or adenopathies in the others, thus guiding the diagnostic biopsy in those with hypermetabolism. In conclusion, FDG PET/CT may be useful in detecting and selecting bone lesions and lymph nodes for biopsy in patients with suspected POEMS syndrome., (Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2010
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