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Your search keyword '"Uemura, Shigeru"' showing total 6 results
Start Over Author "Uemura, Shigeru" Journal european journal of pediatrics
6 results on '"Uemura, Shigeru"'

5. 1p36 deletion syndrome with intestinal malrotation and annular pancreas

Author

Minami, Koichi, primary, Boshi, Haruna, additional, Minami, Takaomi, additional, Tamura, Akira, additional, Yanagawa, Toshihiko, additional, Uemura, Shigeru, additional, Takifuji, Katsunari, additional, Kurosawa, Kenji, additional, Tsukino, Ryuichi, additional, Izumi, Genkichi, additional, and Yoshikawa, Norishige, additional

Published
2004
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6. Effects of immunoglobulin and gamma-interferon on the production of tumour necrosis factor-alpha and interleukin-1 beta by peripheral blood monocytes in the acute phase of Kawasaki disease.

Author

Suzuki, Hiroyuki, Uemura, Shigeru, Tone, Shigenobu, Iizuka, Tadashi, Koike, Michio, Hirayama, Kenji, Maeda, Jiro, Suzuki, H, Uemura, S, Tone, S, Iizuka, T, Koike, M, Hirayama, K, and Maeda, J

Subjects
THERAPEUTIC use of interferons, CELL culture, DOSE-effect relationship in pharmacology, IMMUNIZATION, INTERLEUKIN-1, MONOCYTES, MUCOCUTANEOUS lymph node syndrome, TUMOR necrosis factors, TREATMENT effectiveness, ACUTE diseases, THERAPEUTICS
Abstract

In order to study the in vitro effects of intact immunoglobulin (Ig) and gamma-interferon (INF-gamma) in patients with Kawasaki disease, the production of tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) was measured in peripheral blood monocytes (PBM) both before and after intravenous immunoglobulin (IVIG) therapy. Spontaneous production of TNF-alpha and IL-1 beta both before and after IVIG therapy was significantly higher than in healthy controls. Intact Ig enhanced in vitro the production of TNF-alpha and IL-1 beta both before and after IVIG therapy approximately 3-4 times as compared to the spontaneous production. INF-gamma did not affect the production of the two cytokines. Ig enhanced IL-1 beta mRNA expression in PBM of KD by 3-8 times more than that of spontaneous production. [ABSTRACT FROM AUTHOR]

Published
1996
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