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Start Over Author "Katrien Sabbe" Journal european journal of organic chemistry
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1. Synthesis of 14,20-Bis-epi-1α,25-dihydroxy-19-norvitamin D3 and Analogues

Author

Katrien Sabbe, Maurits Vandewalle, Michiel Van Gool, and Xu-yang Zhao

Subjects
chemistry.chemical_classification, Vitamin, chemistry.chemical_compound, Ketone, Chemistry, Stereochemistry, Organic Chemistry, Diol, Side chain, Organic chemistry, Total synthesis, Physical and Theoretical Chemistry
Abstract

14,20-Bis-epi-1α,25-dihydroxy-19-norvitamin D3 and side chain analogues thereof have been synthesised via the 14,20-bis-epi-Inhoffen–Lythgoe diol 9. The synthesis of this precursor was performed via degradation of vitamin D2 and by total synthesis starting from Hajos–Wiechert ketone 24.

Published
1999

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