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Your search keyword '"Gerke, Oke"' showing total 20 results
Start Over Author "Gerke, Oke" Journal european journal of nuclear medicine and molecular imaging
20 results on '"Gerke, Oke"'

1. Identifying the primary tumour in patients with cancer of unknown primary (CUP) using [18F]FDG PET/CT: a systematic review and individual patient data meta-analysis

Author

Willemse, Jeroen R. J., Lambregts, Doenja M. J., Balduzzi, Sara, Schats, Winnie, Snaebjornsson, Petur, Marchetti, Serena, Vollebergh, Marieke A., van Golen, Larissa W., Cheung, Zing, Vogel, Wouter V., Bodalal, Zuhir, Rostami, Sajjad, Gerke, Oke, Sivakumaran, Tharani, Beets-Tan, Regina G.H., and Lahaye, Max J.

Published
2024
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4. Comparison of 18F-sodium fluoride uptake in the whole bone, pelvis, and femoral neck of multiple myeloma patients before and after high-dose therapy and conventional-dose chemotherapy

Author

Zirakchian Zadeh, Mahdi, Østergaard, Brian, Raynor, William Y., Revheim, Mona-Elisabeth, Seraj, Siavash Mehdizadeh, Acosta-Montenegro, Oswaldo, Ayubcha, Cyrus, Yellanki, Dani P., Al-Zaghal, Abdullah, Nielsen, Anne L., Constantinescu, Caius M., Gerke, Oke, Werner, Thomas J., Zhuang, Hongming, Abildgaard, Niels, Høilund-Carlsen, Poul Flemming, and Alavi, Abass

Published
2020
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18. 18F-sodium fluoride PET/CT provides prognostic clarity compared to calcium and Framingham risk scoring when addressing whole-heart arterial calcification

Author

Sorci, Olivia, primary, Batzdorf, Alexandra S., additional, Mayer, Michael, additional, Rhodes, Sylvia, additional, Peng, Matthew, additional, Jankelovits, Amanda R., additional, Hornyak, Julia N., additional, Gerke, Oke, additional, Høilund-Carlsen, Poul Flemming, additional, Alavi, Abass, additional, and Rajapakse, Chamith S., additional

Published
2019
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19. PET imaging biomarkers in head and neck cancer

Author

Hildebrandt, Malene, Gerke, Oke, Baun, Christina, Falch Braas, Kirsten, Ansholm, J, Farahani, Ziba, Larsen, L, Duvnjak, Sandra, S, Kent, Bak Jylling, Anne Marie, Ewertz, Marianne, Alavi, Abass, and Høilund-Carlsen, Poul Flemming

Subjects
Oncology, medicine.medical_specialty, Imaging biomarker, PET/CT, medicine.medical_treatment, Internal medicine, medicine, Carcinoma, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, Head and neck cancer, PET-CT, medicine.diagnostic_test, business.industry, General Medicine, medicine.disease, Head and neck squamous-cell carcinoma, Radiation therapy, Positron emission tomography, Head and Neck Neoplasms, Positron-Emission Tomography, Carcinoma, Squamous Cell, Molecular imaging, Radiopharmaceuticals, Nuclear medicine, business
Abstract

In locally advanced head and neck squamous cell carcinoma (HNSCC), the role of imaging becomes more and more critical in the management process. In this framework, molecular imaging techniques such as PET allow noninvasive assessment of a range of tumour biomarkers such as metabolism, hypoxia and proliferation, which can serve different purposes. First, in a pretreatment setting they can influence therapy selection strategies and target delineation for radiation therapy. Second, their predictive and/or prognostic value could help enhance the therapeutic ratio in the management of HNSCC. Third, treatment modification can be performed through the generation of a molecular-based heterogeneous dose distribution with dose escalation to the most resistant parts of the tumour, a concept known as dose painting. Fourth, they are increasingly becoming a tool for monitoring response to therapy. In this review, PET imaging biomarkers used in the routine management of HNSCC or under investigation are discussed.

Published
2014

20. Up-front PET/CT changes treatment intent in patients with head and neck squamous cell carcinoma.

Author

Rohde M, Nielsen AL, Johansen J, Sørensen JA, Diaz A, Asmussen JT, Gerke O, Thomassen A, Gyldenkerne N, Døssing H, Bjørndal K, Høilund-Carlsen PF, and Godballe C

Subjects
Fluorodeoxyglucose F18, Humans, Palliative Care, Positron-Emission Tomography, Prospective Studies, Radiopharmaceuticals, Tomography, X-Ray Computed, Carcinoma, Squamous Cell diagnostic imaging, Decision Making, Head and Neck Neoplasms diagnostic imaging, Patient Care Team, Positron Emission Tomography Computed Tomography
Abstract

Purpose: In patients with newly diagnosed head and neck squamous cell carcinoma (HNSCC), we wanted to examine the differences in overall treatment decisions, i.e. curative versus palliative treatment intent, reached by a multidisciplinary team conference (MDTC) based on 18F-fluoro-deoxy-glucose-positron emission tomography/computed tomography (PET/CT) or chest X-ray + MRI of the head and neck (CXR/MRI)., Patients and Methods: This was a prospective blinded cohort study based on paired data. Consecutive patients with histologically verified primary HNSCC were invited to participate. All included patients underwent CXR/MRI and PET/CT before diagnostic biopsy. An ordinary MDTC using all available imaging was conducted as per standard practice. After at least 3 months (to eliminate recall bias in the team), the first project MDTC was conducted, based on either CXR/MRI or PET/CT, and the tumor board drew conclusions regarding treatment. After an additional 3 months, a second project MDTC was conducted using the complementary imaging modality., Results: A total of 307 patients were included. Based on CXR/MRI, 303 patients (99%) were recommended for curative treatment and only four patients (1%) for palliative treatment. Based on PET/CT, the MDTC concluded that 278 (91%) patients were suitable for curative treatment and 29 (9%) patients for palliative treatment. The absolute difference of 8% was statistically significant (95% CI: 4.8%-11.5%, p < 0.001)., Conclusions: A PET/CT-based imaging strategy significantly changed the decisions regarding treatment intent made by a MDTC for patients diagnosed with HNSCC, when compared with the standard imaging strategy of CXR/MRI.

Published
2018
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