Search

Your search keyword '"Hertel-Wulff A"' showing total 2 results
Start Over Author "Hertel-Wulff A" Journal european journal of immunology
2 results on '"Hertel-Wulff A"'

2. Lymphocyte proliferationin vitro induced by soluble protein antigens. II. Cellular requirements

Author

B. Rubin and Birgit Hertel-Wulff

Subjects
T-Lymphocytes, Guinea Pigs, Immunology, Receptors, Antigen, B-Cell, Antigen-Antibody Complex, Lymphocyte proliferation, Biology, Lymphocyte Activation, Antigen, Cell Adhesion, Lymph node stromal cell, medicine, Animals, Immunology and Allergy, Cytotoxic T cell, IL-2 receptor, Antigens, Antigen-presenting cell, Lymph node, Binding Sites, Molecular biology, Immunoglobulin Fc Fragments, B-1 cell, medicine.anatomical_structure, Solubility, Lymph Nodes, Immunologic Memory
Abstract

Immune guinea pig lymph node cells were fractionated on Ig anti-Ig or HSA anti-HSA affinity columns or on plastic surface in medium containing carbonyl iron. These techniques selectively removed B lymphocytes, K lymphocytes or adherent cells. The residual cells (Fc receptor-negative T lymphocytes) responded to soluble antigen in vitro in the same way or even better compared with nonfractionated cells. In addition, there was no indication that antigen-antibody complexes were superior to antigen in triggering lymph node cells or purified lymph code T lymphocytes into DNA synthesis. The results obtained suggested that memory T lymphocytes can be stimulated by antigen autonomously.

Published
1976

Catalog

Books, media, physical & digital resources
See catalog results