113 results
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2. Acetaminophen protein adduct formation following low-dose acetaminophen exposure: comparison of immediate-release vs extended-release formulations
3. Effects of multiple-dose pegylated interferon alfa-2b on the activity of drug-metabolizing enzymes in persons with chronic hepatitis C
4. A systematic review of pharmacokinetics studies in children with protein-energy malnutrition
5. Influence of CYP2C19 genotype on the pharmacokinetics of R483, a CYP2C19 substrate, in healthy subjects and type 2 diabetes patients
6. Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects
7. Variability in drug metabolizing enzyme activity in HIV-infected patients
8. Influences of levodopa on adipose tissue and skeletal muscle metabolism in patients with idiopathic Parkinson’s disease
9. Absolute bioavailability and metabolism of omeprazole in relation to CYP2C19 genotypes following single intravenous and oral administrations
10. Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios
11. Induction of the metabolism of etizolam by carbamazepine in humans
12. Pharmacokinetics of intravenous paracetamol in children and adolescents under major surgery
13. Effect of erythromycin on metabolism of quetiapine in Chinese suffering from schizophrenia
14. Identification of human cytochrome P450s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data
15. Metabolism and elimination of quinine in healthy volunteers
16. Paracetamol and metabolite pharmacokinetics in infants
17. Modulation of midazolam 1-hydroxylation activity in vitro by neurotransmitters and precursors
18. Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6
19. Replacement of (R)-methadone by a double dose of (R, S)-methadone in addicts: interindividual variability of the (R)/(S) ratios and evidence of adaptive changes in methadone pharmacokinetics
20. Pharmacokinetics of moxisylyte in healthy volunteers after intracavernous injection of increasing doses
21. Effects of altitude (4300 M) on the pharmacokinetics of caffeine and cardio-green in humans
22. Inhibitory effects of antiparasitic drugs on cytochrome P450 2D6
23. Early stage autoinduction of carbamazepine metabolism in humans
24. Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone
25. Lack of influence of short-term treatment with propranolol and terbutaline on metabolism and energy expenditure of the Na-K pump in human erythrocytes evaluated by microcalorimetry
26. Formation and excretion of dipyrone metabolites in man
27. Pharmacokinetics of intramuscular nicomorphine and its metabolites in man
28. Enantioselective steady-state kinetics of unbound disopyramide and its dealkylated metabolite in man
29. Ciclosporin metabolite pattern in blood and urine of kidney graft patients in relation to liver function
30. Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH
31. Rapid and slow benzbromarone elimination phenotypes in man: benzbromarone and metabolite profiles
32. Pharmacokinetics and metabolism of iodo-doxorubicin and doxorubicin in humans
33. Single- and multiple-dose pharmacokinetics of R-(−)- and S-(+)-prenylamine in man
34. Metabolism of the diuretic bumetanide in healthy subjects and patients with renal impairment
35. Nonlinear kinetics of propafenone metabolites in healthy man
36. Lack of a kinetic interaction between fluconazole and mexiletine
37. Metabolism and pharmacokinetics of prostaglandin E1 administered by intravenous infusion in human subjects
38. Fibrates and triglyceride metabolism
39. Fibrates and triglyceride metabolism
40. The relationship between debrisoquine oxidation phenotype and the pharmacokinetics of chlorpropamide
41. Diazepam metabolism in human foetal and adult liver
42. Pharmacokinetics of estramustine phosphate (Estracyt®) in prostatic cancer patients
43. Renal clearance of theophylline and its major metabolites: Age and urine flow dependency in paediatric patients
44. The metabolism of amphetamine in dependent subjects
45. Absorption and metabolism in man of 16-epi-gitoxin, a new semi-synthetic cardioactive glycoside
46. Renal excretion and pharmacokinetics of methotrexate and 7-hydroxy-methotrexate following a 24-h high dose infusion of methotrexate in children
47. Preliminary studies of the kinetics of citalopram in man
48. Disposition of monodesethylamodiaquine after a single oral dose of amodiaquine and three regimens for prophylaxis againstPlasmodium falciparum malaria
49. Pinazepam: A precursor of N-desmethyldiazepam
50. Pharmacokinetics of naproxen in subjects with normal and impaired renal function
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