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Start Over "MAYUR CHAUDHARI" Journal european journal of clinical nutrition
2 results on '"MAYUR CHAUDHARI"'

1. Standardized feeding and probiotic supplementation for reducing necrotizing enterocolitis in preterm infants in a resource limited set up

Author

Sandeep Kadam, Sanjay Patole, Saurabh Patel, Mayur Chaudhari, and Shripada Rao

Subjects
Male, medicine.medical_specialty, Birth weight, Medicine (miscellaneous), India, Gestational Age, Infant, Premature, Diseases, Cohort Studies, Feeding Methods, 03 medical and health sciences, 0302 clinical medicine, Enterocolitis, Necrotizing, 030225 pediatrics, Internal medicine, medicine, Birth Weight, Humans, 030212 general & internal medicine, EPOCH (chemotherapy), Retrospective Studies, Enterocolitis, Nutrition and Dietetics, Milk, Human, business.industry, Incidence (epidemiology), Probiotics, Infant, Newborn, Retrospective cohort study, Odds ratio, medicine.disease, digestive system diseases, Infant Formula, body regions, Treatment Outcome, Necrotizing enterocolitis, Dietary Supplements, Female, medicine.symptom, business, psychological phenomena and processes, Infant, Premature, Cohort study
Abstract

Necrotizing enterocolitis (NEC ≥ Stage II) is associated with high mortality and morbidity in preterm infants. To assess if introduction of standardized feeding regimen (SFR) and routine probiotic supplementation (RPS) was associated with reduced incidence of NEC in preterm infants in our nursery in a resource limited set up. This was a retrospective cohort study assessing the incidence of NEC ≥ Stage II before (Epoch 1: N = 144) vs. after (Epoch 2, N = 144) implementation of SFR and RPS in preterm infants

Published
2017

2. Standardized feeding and probiotic supplementation for reducing necrotizing enterocolitis in preterm infants in a resource limited set up

Author

Patel, Saurabh, Chaudhari, Mayur, Kadam, Sandeep, Rao, Shripada, and Patole, Sanjay

Subjects
Necrotizing enterocolitis -- Care and treatment -- Diet therapy, Premature infants -- Food and nutrition, Digestive system research, Probiotics -- Patient outcomes, Mortality, Morbidity, Infants, Pregnancy, Enterocolitis, Food/cooking/nutrition, Health
Abstract

Background/objectives Necrotizing enterocolitis (NEC [greater than or equal to] Stage II) is associated with high mortality and morbidity in preterm infants. To assess if introduction of standardized feeding regimen (SFR) and routine probiotic supplementation (RPS) was associated with reduced incidence of NEC in preterm infants in our nursery in a resource limited set up. Subjects/methods This was a retrospective cohort study assessing the incidence of NEC [greater than or equal to] Stage II before (Epoch 1: N = 144) vs. after (Epoch 2, N = 144) implementation of SFR and RPS in preterm infants < 35 weeks. Results The median (IQR) gestation and birth weight in epoch 1 and epoch 2 was [32 (30, 33.5) vs. 31.5 (30, 34) weeks, p = 0.829], and [1350 (1100, 1700) vs. 1370 (1110, 1550) g, p = 0.363] respectively. Both groups had predominantly outborn infants (Epoch 1: 79.2% vs. Epoch 2: 78.2%; p = 1.00). Multivariate analysis after adjusting for potential confounders found a significantly lower incidence of NEC [greater than or equal to] Stage II after implementing SFR and RPS (Epoch 1: 17.4% vs. Epoch 2:9.0%, adjusted odds ratio aOR: 0.19; 95% CI: 0.05, 0.71, p = 0.013). The incidence of the composite outcome of 'NEC or Mortality' was also significantly lower after the intervention (Epoch 1: 21.5% vs. Epoch 2: 14.6%; aOR 0.24, 95% CI: 0.07, 0.85, p = 0.027). Conclusions Introduction of SFR and RPS was associated with significant reduction in NEC [greater than or equal to] Stage II and the composite outcome of NEC [greater than or equal to] Stage II /mortality in preterm infants., Author(s): Saurabh Patel [sup.1] , Mayur Chaudhari [sup.1] , Sandeep Kadam [sup.1] , Shripada Rao [sup.2] , Sanjay Patole [sup.2] Author Affiliations: (1) Department of Neonatology, Ratna Memorial Hospital, Pune, [...]

Published
2018
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