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Your search keyword '"Boffetta, Paolo."' showing total 182 results
Start Over Author "Boffetta, Paolo." Journal european journal of cancer prevention
182 results on '"Boffetta, Paolo."'

1. Mushroom consumption and risk of gastric cancer: a pooled analysis within the stomach cancer pooling project and a combined meta-analysis with other observational studies.

Author

Ba, Djibril, Ssentongo, Paddy, Pelucchi, Claudio, Negri, Eva, Palli, Domenico, Ferraroni, Monica, Yu, Guo-Pei, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson, Zaridze, David, Maximovich, Dmitry, Obón-Santacana, Mireia, Álvarez-Álvarez, Laura, Vioque, Jesus, Garcia de la Hera, Manoli, López-Carrillo, Lizbeth, López-Cervantes, Malaquias, Mu, Lina, Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Camargo, Maria, Curado, Maria, Lunet, Nuno, La Vecchia, Carlo, Muscat, Joshua, and Zhang, Zuofeng

Subjects
Humans, Stomach Neoplasms, Risk Factors, Agaricales, Risk, Asia
Abstract

Edible mushrooms have high concentrations of vitamins and minerals. They are considered functional foods for their disease-prevention properties. Mushroom consumption may reduce the risk of gastric cancer, the fifth most common cancer worldwide. We investigated the association between mushroom consumption and gastric cancer risk in a pooled analysis within the Stomach Cancer Pooling (StoP) Project and in a meta-analysis that also included previously published studies. A total of 3900 gastric cancer cases and 7792 controls from 11 studies were included in the StoP analysis. Mushroom consumption was measured using food frequency questionnaires. Higher mushroom consumption was associated with a lower risk of gastric cancer [relative risk (RR) for the highest vs. lowest consumption categories, 0.82; 95% confidence interval (CI), 0.71-0.95]. The corresponding RRs were 0.59 (95% CI, 0.26-1.33) in a meta-analysis of four previously published studies and 0.77 for all studies combined (95% CI, 0.63-0.95; n = 15 studies). In geographic subgroup analysis, the pooled risk in Western Pacific countries was (RR, 0.59; 95% CI, 0.40-0.87; n = 6). The stronger effect in Asian countries may reflect high level of antioxidants in mushroom species consumed in Asia.

Published
2023

2. The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium

Author

Dabo, Bashir, Pelucchi, Claudio, Rota, Matteo, Jain, Harshonnati, Bertuccio, Paola, Bonzi, Rossella, Palli, Domenico, Ferraroni, Monica, Zhang, Zuo-Feng, Sanchez-Anguiano, Aurora, Pham, Yen Thi-Hai, Tran, Chi Thi-Du, Pham, Anh Gia, Yu, Guo-Pei, Nguyen, Tin C, Muscat, Joshua, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson S, Zaridze, David, Maximovitch, Dmitry, Kogevinas, Manolis, de Larrea, Nerea Fernàndez, Boccia, Stefania, Pastorino, Roberta, Kurtz, Robert C, Lagiou, Areti, Lagiou, Pagona, Vioque, Jesus, Camargo, M Constanza, Curado, Maria Paula, Lunet, Nuno, Boffetta, Paolo, Negri, Eva, La Vecchia, Carlo, and Luu, Hung N

Subjects
Epidemiology, Health Sciences, Infectious Diseases, Prevention, Cancer, Stomach Cancer, Digestive Diseases, Emerging Infectious Diseases, Rare Diseases, Diabetes, Metabolic and endocrine, Stroke, Case-Control Studies, Diabetes Mellitus, Type 2, Helicobacter Infections, Helicobacter pylori, Humans, Risk Factors, Stomach Neoplasms, diabetes, gastric cancer, risk factors, Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis, Public health
Abstract

BackgroundPrior epidemiologic studies on the association between diabetes and gastric cancer risk provided inconclusive findings, while traditional, aggregate data meta-analyses were characterized by high between-study heterogeneity.ObjectiveTo investigate the association between type 2 diabetes and gastric cancer using data from the 'Stomach Cancer Pooling (StoP) Project', an international consortium of more than 30 case-control and nested case-control studies, which is large and provides harmonized definition of participants' characteristics across individual studies. The data have the potential to minimize between-study heterogeneity and provide greater statistical power for subgroup analysis.MethodsWe included 5592 gastric cancer cases and 12 477 controls from 14 studies from Europe, Asia, North America, and South America in a two-stage individual-participant data meta-analysis. Random-effect models were used to estimate summary odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) by pooling study-specific ORs.ResultsWe did not find an overall association between diabetes and gastric cancer (pooled OR = 1.01, 95% CI, 0.94-1.07). However, the risk of cardia gastric cancer was significantly higher among individuals with type 2 diabetes (OR = 1.16, 95% CI, 1.02-1.33). There was no association between diabetes and gastric cancer risk in strata of Helicobacter pylori infection serostatus, age, sex, BMI, smoking status, alcohol consumption, fruit/vegetable intake, gastric cancer histologic type, and source of controls.ConclusionThis study provides additional evidence that diabetes is unrelated to gastric cancer overall but may be associated with excess cardia gastric cancer risk.

Published
2022

3. Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium

Author

Martimianaki, Georgia, Bertuccio, Paola, Alicandro, Gianfranco, Pelucchi, Claudio, Bravi, Francesca, Carioli, Greta, Bonzi, Rossella, Rabkin, Charles S, Liao, Linda M, Sinha, Rashmi, Johnson, Ken, Hu, Jinfu, Palli, Domenico, Ferraroni, Monica, Lunet, Nuno, Morais, Samantha, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson Shigueaki, López-Carrillo, Lizbeth, Hernández-Ramírez, Raúl Ulises, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Martin, Vicente, Ward, Mary H, Vioque, Jesus, de la Hera, Manoli Garcia, Zhang, Zuo-Feng, Kurtz, Robert C, Lagiou, Pagona, Lagiou, Areti, Trichopoulou, Antonia, Karakatsani, Anna, Malekzadeh, Reza, Camargo, M Constanza, Curado, Maria Paula, Boccia, Stefania, Boffetta, Paolo, Negri, Eva, and La Vecchia, Carlo

Subjects
Clinical Research, Cancer, Coffee, Humans, Logistic Models, Observational Studies as Topic, Odds Ratio, Risk Factors, Stomach Neoplasms, cardia cancer, case-control study, coffee, gastric cancer, pooled analysis, Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis
Abstract

ObjectiveThis study aimed to evaluate and quantify the relationship between coffee and gastric cancer using a uniquely large dataset from an international consortium of observational studies on gastric cancer, including data from 18 studies, for a total of 8198 cases and 21 419 controls.MethodsA two-stage approach was used to obtain the pooled odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) for coffee drinkers versus never or rare drinkers. A one-stage logistic mixed-effects model with a random intercept for each study was used to estimate the dose-response relationship. Estimates were adjusted for sex, age and the main recognized risk factors for gastric cancer.ResultsCompared to never or rare coffee drinkers, the estimated pooled OR for coffee drinkers was 1.03 (95% CI, 0.94-1.13). When the amount of coffee intake was considered, the pooled ORs were 0.91 (95% CI, 0.81-1.03) for drinkers of 1-2 cups per day, 0.95 (95% CI, 0.82-1.10) for 3-4 cups, and 0.95 (95% CI, 0.79-1.15) for five or more cups. An OR of 1.20 (95% CI, 0.91-1.58) was found for heavy coffee drinkers (seven or more cups of caffeinated coffee per day). A positive association emerged for high coffee intake (five or more cups per day) for gastric cardia cancer only.ConclusionsThese findings better quantify the previously available evidence of the absence of a relevant association between coffee consumption and gastric cancer.

Published
2021

11. Mouthwash use and cancer of the head and neck

Author

Boffetta, Paolo, Hayes, Richard B, Sartori, Samantha, Lee, Yuan-Chin A, Muscat, Joshua, Olshan, Andrew, Winn, Deborah M, Castellsagué, Xavier, Zhang, Zuo-Feng, Morgenstern, Hal, Chen, Chu, Schwartz, Stephen M, Vaughan, Thomas L, Wunsch-Filho, Victor, Purdue, Mark, Koifman, Sergio, Curado, Maria P, Vilensky, Marta, Gillison, Maura, Fernandez, Leticia, Menezes, Ana, Daudt, Alexander W, Schantz, Stimson, Yu, Guopei, D’Souza, Gypsyamber, Haddad, Robert I, La Vecchia, Carlo, and Hashibe, Mia

Subjects
Health Services and Systems, Biomedical and Clinical Sciences, Health Sciences, Tobacco, Digestive Diseases, Prevention, Tobacco Smoke and Health, Cancer, Dental/Oral and Craniofacial Disease, Substance Misuse, Oral and gastrointestinal, Good Health and Well Being, Adult, Case-Control Studies, Female, Follow-Up Studies, Head and Neck Neoplasms, Humans, International Agencies, Male, Meta-Analysis as Topic, Mouthwashes, Prevalence, Prognosis, Retrospective Studies, Risk Factors, alcohol, head and neck cancer, laryngeal cancer, mouthwash, oral cancer, pharyngeal cancer, Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis, Public health
Abstract

Most mouthwashes contain alcohol, a known cause of head and neck cancer (oral cavity, pharynx, larynx), likely through the carcinogenic activity of acetaldehyde, formed in the oral cavity from alcohol. We carried out a pooled analysis of 8981 cases of head and neck cancer and 10 090 controls from 12 case-control studies with comparable information on mouthwash use in the International Head and Neck Cancer Epidemiology Consortium. Logistic regression was used to assess the association of mouthwash use with cancers of the oral cavity, oropharynx, hypopharynx, and larynx, adjusting for study, age, sex, pack-years of tobacco smoking, number of alcoholic drinks/day, and education. Compared with never users of mouthwash, the odds ratio (OR) of all head and neck cancers was 1.01 [95% confidence interval (CI): 0.94-1.08] for ever users, based on 12 studies. The corresponding ORs of cancer of the oral cavity and oropharynx were 1.11 (95% CI: 1.00-1.23) and 1.28 (95% CI: 1.06-1.56), respectively. OR for all head and neck cancer was 1.15 (95% CI: 1.01-1.30) for use for more than 35 years, based on seven studies (P for linear trend=0.01), and OR 1.31 (95% CI: 1.09-1.58) for use more than one per day, based on five studies (P for linear trend

Published
2016

13. Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium

Author

Martimianaki, Georgia, Bertuccio, Paola, Alicandro, Gianfranco, Pelucchi, Claudio, Bravi, Francesca, Carioli, Greta, Bonzi, Rossella, Rabkin, Charles S., Liao, Linda M., Sinha, Rashmi, Johnson, Ken, Hu, Jinfu, Palli, Domenico, Ferraroni, Monica, Lunet, Nuno, Morais, Samantha, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson Shigueaki, López-Carrillo, Lizbeth, Hernández-Ramírez, Raúl Ulises, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Martin, Vicente, Ward, Mary H., Vioque, Jesus, Garcia de la Hera, Manoli, Zhang, Zuo-Feng, Kurtz, Robert C., Lagiou, Pagona, Lagiou, Areti, Trichopoulou, Antonia, Karakatsani, Anna, Malekzadeh, Reza, Camargo, M. Constanza, Curado, Maria Paula, Boccia, Stefania, Boffetta, Paolo, Negri, Eva, and La Vecchia, Carlo

Published
2022
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18. Cigarette smoking and gastric cancer in the Stomach Cancer Pooling (StoP) Project

Author

Praud, Delphine, Rota, Matteo, Pelucchi, Claudio, Bertuccio, Paola, Rosso, Tiziana, Galeone, Carlotta, Zhang, Zuo-Feng, Matsuo, Keitaro, Ito, Hidemi, Hu, Jinfu, Johnson, Kenneth C., Yu, Guo-Pei, Palli, Domenico, Ferraroni, Monica, Muscat, Joshua, Lunet, Nuno, Peleteiro, Bárbara, Malekzadeh, Reza, Ye, Weimin, Song, Huan, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Castaño-Vinyals, Gemma, Vioque, Jesus, Navarrete-Muñoz, Eva M., Pakseresht, Mohammadreza, Pourfarzi, Farhad, Wolk, Alicja, Orsini, Nicola, Bellavia, Andrea, Håkansson, Niclas, Mu, Lina, Pastorino, Roberta, Kurtz, Robert C., Derakhshan, Mohammad H., Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Boccia, Stefania, Negri, Eva, and La Vecchia, Carlo

Published
2018

22. Tobacco smoking and gastric cancer : meta-analyses of published data versus pooled analyses of individual participant data (StoP Project)

Author

Ferro, Ana, Morais, Samantha, Rota, Matteo, Pelucchi, Claudio, Bertuccio, Paola, Bonzi, Rossella, Galeone, Carlotta, Zhang, Zuo-Feng, Matsuo, Keitaro, Ito, Hidemi, Hu, Jinfu, Johnson, Kenneth C., Yu, Guo-Pei, Palli, Domenico, Ferraroni, Monica, Muscat, Joshua, Ye, Weimin, Song, Huan, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Castaño-Vinyals, Gemma, Vioque, Jesus, Navarrete-Muñoz, Eva M., Pakseresht, Mohammadreza, Pourfarzi, Farhad, Wolk, Alicja, Orsini, Nicola, Bellavia, Andrea, Håkansson, Niclas, Mu, Lina, Pastorino, Roberta, Kurtz, Robert C., Derakhshan, Mohammad H., Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Boccia, Stefania, Negri, Eva, La Vecchia, Carlo, Peleteiro, Bárbara, and Lunet, Nuno

Published
2018

25. Gallbladder disease, cholecystectomy, and pancreatic cancer risk in the International Pancreatic Cancer Case-Control Consortium (PanC4)

Author

Rosato, Valentina, Negri, Eva, Bosetti, Cristina, Malats, Núria, Gomez-Rubio, Paulina, Consortium, PanGenEU, Maisonneuve, Patrick, Miller, Anthony B., Bueno-de-Mesquita, H. Bas, Baghurst, Peter A., Zatonski, Witold, Petersen, Gloria M., Scelo, Ghislaine, Holcatova, Ivana, Fabianova, Eleonora, Serraino, Diego, Olson, Sara H., Vioque, Jesús, Lagiou, Pagona, Duell, Eric J., Boffetta, Paolo, and La Vecchia, Carlo

Published
2020
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33. Food preparation methods, drinking water source, and esophageal squamous cell carcinoma in the high-risk area of Golestan, Northeast Iran

Author

Golozar, Asieh, Etemadi, Arash, Kamangar, Farin, Malekshah, Akbar Fazeltabar, Islami, Farhad, Nasrollahzadeh, Dariush, Abedi-Ardekani, Behnoosh, Khoshnia, Masoud, Pourshams, Akram, Semnani, Shahriar, Marjani, Haji Amin, Shakeri, Ramin, Sotoudeh, Masoud, Brennan, Paul, Taylor, Philip, Boffetta, Paolo, Abnet, Christian, Dawsey, Sanford, and Malekzadeh, Reza

Published
2016

41. The stomach cancer pooling (StoP) project : study design and presentation

Author

Pelucchi, Claudio, Lunet, Nuno, Boccia, Stefania, Zhang, Zuo-Feng, Praud, Delphine, Boffetta, Paolo, Levi, Fabio, Matsuo, Keitaro, Ito, Hidemi, Hu, Jinfu, Johnson, Kenneth C., Ferraroni, Monica, Yu, Guo-Pei, Peleteiro, Bárbara, Malekzadeh, Reza, Derakhshan, Mohammad H., Ye, Weimin, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Martín, Vicente, Pakseresht, Mohammadreza, Pourfarzi, Farhad, Bellavia, Andrea, Orsini, Nicola, Wolk, Alicja, Mu, Lina, Arzani, Dario, Kurtz, Robert C., Lagiou, Pagona, Trichopoulos, Dimitrios, Muscat, Joshua, La Vecchia, Carlo, and Negri, Eva

Published
2015

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