1. Time-series analysis of heart rate and blood pressure in response to changes in work rate before and after 60 days of 6° head down tilt bed rest
- Author
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Uwe Hoffmann, Jessica Koschate, Uwe Drescher, Tania Zieschang, and L. Thieschäfer
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cardiovascular reflex responses ,Physiology ,medicine.medical_treatment ,Time series analysis ,Blood Pressure ,030204 cardiovascular system & hematology ,Work rate ,Bed rest ,Head-Down Tilt ,03 medical and health sciences ,0302 clinical medicine ,Heart Rate ,Physiology (medical) ,Internal medicine ,Heart rate ,Humans ,Medicine ,Cycle ergometer ,Orthopedics and Sports Medicine ,business.industry ,Public Health, Environmental and Occupational Health ,030229 sport sciences ,General Medicine ,Human physiology ,Blood pressure ,Cardiology ,Jump ,Original Article ,business - Abstract
Purpose Cardiovascular regulation during exercise, described using time series analysis, is expected to be attenuated after bed rest (BR) and this effect will be dampened by a reactive jumps countermeasure. Methods Twenty subjects (29 ± 6 years, 23.6 ± 1.7 kg m−2) were tested on a cycle ergometer 9 days (BDC-9) before the beginning of BR as well as 2 (R + 2) and 13 days (R + 13) after the end of BR, applying moderate pseudo-random binary (PRBS) work rate changes. Heart rate (HR) and mean arterial blood pressure (mBP) were measured beat-to-beat and interpolated to 1 s intervals. HR and mBP were cross-correlated [CCF(HR-mBP)] during the PRBS. Eleven subjects participated in a reactive jump countermeasure (JUMP) during the BR period, the other part of the group served as control group (CTRL). Results In the CTRL group, significantly lower CCF(HR-mBP) values during BDC-9 were observed compared to R + 2 during the lags 20–25 s and significantly higher values during the lags − 39 s to − 35 s. In the JUMP group, significantly lower CCFs were only observed at R + 2 compared with BDC-9 during the lags 23 s and 24 s, whereas the CCFs for BDC-9 were significantly higher at several lags compared with R + 13. Conclusion Attenuations in the regulation of the cardiovascular system during cycling exercise after BR were found in the CTRL group of the RSL study. Cardiovascular regulation in the JUMP group was improved compared to values before the beginning of BR, suggesting the effectiveness of the reactive jumps countermeasure to mitigate the deleterious effects of prolonged BR.
- Published
- 2020