1. Doppler Echocardiographic Measurements in Normal Chinese Adults (EMINCA): a prospective, nationwide, and multicentre study
- Author
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Gui-Hua, Yao, Mei, Zhang, Li-Xue, Yin, Cheng, Zhang, Ming-Jun, Xu, Yan, Deng, Yan, Liu, You-Bin, Deng, Wei-Dong, Ren, Zhi-An, Li, Hong, Tang, Quan-Bin, Zhang, Yu-Ming, Mu, Li-Gang, Fang, Yun, Zhang, and Ya, Yang
- Subjects
Adult ,Male ,China ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Heart Ventricles ,Population ,030204 cardiovascular system & hematology ,Doppler echocardiography ,Ventricular Function, Left ,Body Mass Index ,03 medical and health sciences ,symbols.namesake ,Age Distribution ,0302 clinical medicine ,Reference Values ,Risk Factors ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Heart Atria ,Prospective Studies ,030212 general & internal medicine ,Sex Distribution ,education ,Prospective cohort study ,Aged ,education.field_of_study ,medicine.diagnostic_test ,business.industry ,Reproducibility of Results ,Chinese adults ,General Medicine ,Middle Aged ,Echocardiography, Doppler ,Healthy Volunteers ,Reference values ,Cohort ,symbols ,Female ,Cardiology and Cardiovascular Medicine ,business ,Body mass index ,Doppler effect - Abstract
Aims Currently, available Doppler echocardiographic reference values are derived mainly from North American and European population studies, which may not applicable to the Chinese population. We aimed to establish normal reference values of Doppler echocardiographic parameters in a nationwide, population-based cohort of healthy Han Chinese adults. Methods and results A total of 1394 qualified healthy subjects (mean age 47.3 ± 16.0 years, 678 men) were enrolled at 43 collaborating laboratories, 37 transvalvular flow and tissue Doppler parameters were obtained, and the impacts of gender and age on each parameter were analysed. Significant differences were found between men and women in 48.6% (18/37) of the parameters analysed, and among different age groups in 83.8% (31/37) of the parameters in men and in 86.5% (32/37) of the parameters in women. Conclusions Normal reference values of Doppler echocardiographic parameters were established for the first time in a nationwide, population-based cohort of healthy Han Chinese adults. Since most of these parameters differed by gender and/or age, reference values specified for gender and age should be recommended in clinical practice. [10.1093/ehjci/jev353][1] [1]: /lookup/doi/10.1093/ehjci/jev353
- Published
- 2015
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