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Start Over Author "Im, KyungAh" Journal european heart journal
8 results on '"Im, KyungAh"'

2. Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12 inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54

Author

Bonaca, Marc P., Bhatt, Deepak L., Steg, P. Gabriel, Storey, Robert F., Cohen, Marc, Im, Kyungah, Oude Ophuis, Ton, Budaj, Andrej, Goto, Shinya, López-Sendón, José, Diaz, Rafael, Dalby, Anthony, Van de Werf, Frans, Ardissino, Diego, Montalescot, Gilles, Aylward, Philip, Magnani, Giulia, Jensen, Eva C., Held, Peter, Braunwald, Eugene, and Sabatine, Marc S.

Published
2016
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3. Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial

Author

Magnani, Giulia, Storey, Robert F., Steg, Gabriel, Bhatt, Deepak L., Cohen, Marc, Kuder, Julia, Im, Kyungah, Aylward, Philip, Ardissino, Diego, Isaza, Daniel, Parkhomenko, Alexander, Goudev, Assen R., Dellborg, Mikael, Kontny, Frederic, Corbalan, Ramon, Medina, Felix, Jensen, Eva C., Held, Peter, Braunwald, Eugene, Sabatine, Marc S., and Bonaca, Marc P.

Published
2016
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4. Long-term ticagrelor for secondary prevention in patients with prior myocardial infarction and no history of coronary stenting: insights from PEGASUS-TIMI 54

Author

Furtado, Remo H M, primary, Nicolau, Jose C, additional, Magnani, Giulia, additional, Im, Kyungah, additional, Bhatt, Deepak L, additional, Storey, Robert F, additional, Steg, P Gabriel, additional, Spinar, Jindrich, additional, Budaj, Andrzej, additional, Kontny, Frederic, additional, Corbalan, Ramon, additional, Kiss, Robert G, additional, Abola, Maria Teresa, additional, Johanson, Per, additional, Jensen, Eva C, additional, Braunwald, Eugene, additional, Sabatine, Marc S, additional, and Bonaca, Marc P, additional

Published
2019
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5. Long-term ticagrelor for secondary prevention in patients with prior myocardial infarction and no history of coronary stenting: insights from PEGASUS-TIMI 54.

Author

Furtado, Remo H M, Nicolau, Jose C, Magnani, Giulia, Im, Kyungah, Bhatt, Deepak L, Storey, Robert F, Steg, P Gabriel, Spinar, Jindrich, Budaj, Andrzej, Kontny, Frederic, Corbalan, Ramon, Kiss, Robert G, Abola, Maria Teresa, Johanson, Per, Jensen, Eva C, Braunwald, Eugene, Sabatine, Marc S, and Bonaca, Marc P

Abstract

Aims PEGASUS-TIMI 54 demonstrated that long-term dual antiplatelet therapy (DAPT) with aspirin and ticagrelor reduced the risk of major adverse cardiovascular events (MACE), with an acceptable increase in bleeding, in patients with prior myocardial infarction (MI). While much of the discussion around prolonged DAPT has been focused on stented patients, patients with prior MI without prior coronary stenting comprise a clinically important subgroup. Methods and results This was a pre-specified analysis from PEGASUS-TIMI 54, which randomized 21 162 patients with prior MI (1–3 years) and additional high-risk features to ticagrelor 60 mg, 90 mg, or placebo twice daily in addition to aspirin. A total of 4199 patients had no history of coronary stenting at baseline. The primary efficacy outcome (MACE) was the composite of cardiovascular death, MI, or stroke. Patients without history of coronary stenting had higher baseline risk of MACE [13.2% vs. 8.0%, adjusted hazard ratio (HR) 1.41, 95% confidence interval (CI) 1.15–1.73, in the placebo arm]. The relative risk reduction in MACE with ticagrelor (pooled doses) was similar in patients without (HR 0.82, 95% CI 0.68–0.99) and with prior stenting (HR 0.85, 95% CI 0.75–0.96; P for interaction = 0.76). Conclusion Long-term ticagrelor reduces thrombotic events in patients with prior MI regardless of whether they had prior coronary stenting. These data highlight the benefits of DAPT in prevention of spontaneous atherothrombotic events and indicate that long-term ticagrelor may be considered in high-risk patients with prior MI even if they have not been treated with stenting. ClinicalTrials.gov Identifier NCT01225562. Open in new tab Download slide Open in new tab Download slide [ABSTRACT FROM AUTHOR]

Published
2020
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6. Modes and timing of death in 66 252 patients with non-ST-segment elevation acute coronary syndromes enrolled in 14 TIMI trials

Author

Berg, David D, primary, Wiviott, Stephen D, additional, Braunwald, Eugene, additional, Guo, Jianping, additional, Im, KyungAh, additional, Kashani, Amir, additional, Gibson, C Michael, additional, Cannon, Christopher P, additional, Morrow, David A, additional, Bhatt, Deepak L, additional, Mega, Jessica L, additional, O’Donoghue, Michelle L, additional, Antman, Elliott M, additional, Newby, L Kristin, additional, Sabatine, Marc S, additional, and Giugliano, Robert P, additional

Published
2018
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7. Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54

Author

Bonaca, Marc P., primary, Bhatt, Deepak L., additional, Steg, P. Gabriel, additional, Storey, Robert F., additional, Cohen, Marc, additional, Im, Kyungah, additional, Oude Ophuis, Ton, additional, Budaj, Andrej, additional, Goto, Shinya, additional, López-Sendón, José, additional, Diaz, Rafael, additional, Dalby, Anthony, additional, Van de Werf, Frans, additional, Ardissino, Diego, additional, Montalescot, Gilles, additional, Aylward, Philip, additional, Magnani, Giulia, additional, Jensen, Eva C., additional, Held, Peter, additional, Braunwald, Eugene, additional, and Sabatine, Marc S., additional

Published
2015
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8. Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial

Author

Magnani, Giulia, primary, Storey, Robert F., additional, Steg, Gabriel, additional, Bhatt, Deepak L., additional, Cohen, Marc, additional, Kuder, Julia, additional, Im, Kyungah, additional, Aylward, Philip, additional, Ardissino, Diego, additional, Isaza, Daniel, additional, Parkhomenko, Alexander, additional, Goudev, Assen R., additional, Dellborg, Mikael, additional, Kontny, Frederic, additional, Corbalan, Ramon, additional, Medina, Felix, additional, Jensen, Eva C., additional, Held, Peter, additional, Braunwald, Eugene, additional, Sabatine, Marc S., additional, and Bonaca, Marc P., additional

Published
2015
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