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3. European Society of Cardiology

Author

Timmis, Adam, Vardas, Panos, Townsend, Nick, Torbica, Aleksandra, Katus, Hugo, De Smedt, Delphine, Gale, Chris P, Maggioni, Aldo P, Petersen, Steffen E, Huculeci, Radu, Kazakiewicz, Dzianis, de Benito Rubio, Victor, Ignatiuk, Barbara, Raisi-Estabragh, Zahra, Pawlak, Agnieszka, Karagiannidis, Efstratios, Treskes, Roderick, Gaita, Dan, Beltrame, John F, McConnachie, Alex, Bardinet, Isabel, Graham, Ian, Flather, Marcus, Elliott, Perry, Mossialos, Elias A, Weidinger, Franz, Achenbach, Stephan, Meeder, J. G., van Rossum, AC, Elsendoorn, N., ACS - Heart failure & arrhythmias, and Cardiology

Subjects
Adult, Male, Health infrastructure, Statistics, Cardiology, Cardiovascular disease, Cardiovascular System, European Society of Cardiology, Cardiovascular Diseases, Risk Factors, Income, Humans, Female, Service provision, Mortality, Morbidity, Cardiology and Cardiovascular Medicine
Abstract

Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) statistics for the 57 ESC member countries. Methods and results Statistics pertaining to 2019, or the latest available year, are presented. Data sources include the World Health Organization, the Institute for Health Metrics and Evaluation, the World Bank, and novel ESC sponsored data on human and capital infrastructure and cardiovascular healthcare delivery. New material in this report includes sociodemographic and environmental determinants of CVD, rheumatic heart disease, out-of-hospital cardiac arrest, left-sided valvular heart disease, the advocacy potential of these CVD statistics, and progress towards World Health Organization (WHO) 2025 targets for non-communicable diseases. Salient observations in this report: (i) Females born in ESC member countries in 2018 are expected to live 80.8 years and males 74.8 years. Life expectancy is longer in high income (81.6 years) compared with middle-income (74.2 years) countries. (ii) In 2018, high-income countries spent, on average, four times more on healthcare than middle-income countries. (iii) The median PM2.5 concentrations in 2019 were over twice as high in middle-income ESC member countries compared with high-income countries and exceeded the EU air quality standard in 14 countries, all middle-income. (iv) In 2016, more than one in five adults across the ESC member countries were obese with similar prevalence in high and low-income countries. The prevalence of obesity has more than doubled over the past 35 years. (v) The burden of CVD falls hardest on middle-income ESC member countries where estimated incidence rates are ∼30% higher compared with high-income countries. This is reflected in disability-adjusted life years due to CVD which are nearly four times as high in middle-income compared with high-income countries. (vi) The incidence of calcific aortic valve disease has increased seven-fold during the last 30 years, with age-standardized rates four times as high in high-income compared with middle-income countries. (vii) Although the total number of CVD deaths across all countries far exceeds the number of cancer deaths for both sexes, there are 15 ESC member countries in which cancer accounts for more deaths than CVD in males and five-member countries in which cancer accounts for more deaths than CVD in females. (viii) The under-resourced status of middle-income countries is associated with a severe procedural deficit compared with high-income countries in terms of coronary intervention, ablation procedures, device implantation, and cardiac surgical procedures. Conclusion Risk factors and unhealthy behaviours are potentially reversible, and this provides a huge opportunity to address the health inequalities across ESC member countries that are highlighted in this report. It seems clear, however, that efforts to seize this opportunity are falling short and present evidence suggests that most of the WHO NCD targets for 2025 are unlikely to be met across ESC member countries.

Published
2022

4. The continuum of personalized cardiovascular medicine: a position paper of the European Society of Cardiology

Author

Kirchhof, Paulus, Sipido, Karin R., Cowie, Martin R., Eschenhagen, Thomas, Fox, Keith A.A., Katus, Hugo, Schroeder, Stefan, Schunkert, Heribert, Priori, Silvia, Alonso, Angeles, Chezaubernard, Claire, Doevendans, Pieter, Eschenhagen, Thomas, Fox, Keith, Katus, Hugo, Khder, Yasser, Kirchhof, Paulus, Kramer, Frank, Kristensen, Steen, Maitland-Van der Zee, Anke-Hilse, Oertelt-Prigione, Sabine, Pinto, Fausto, Pocock, Stuart, Priori, Silvia G., Sartorius, Alfonso, Schott, Daniela, Schroeder, Stefan, Schunkert, Heribert, Schwab, Matthias, Sipido, Karin, Svensson, Anders, Swedberg, Karl, Wallentin, Lars, Weimers, Marianne, and Herttuala, Seppo Yla

Published
2014
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6. 2019 ESC Guidelines for the management of patients with supraventricular tachycardiaThe Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC)

Author

Brugada, Josep, Katritsis, Demosthenes, Arbelo, Elena, Arribas, Fernando, Bax, Jeroen, Blomström-Lundqvist, Carina, Calkins, Hugh, Corrado, Domenico, Deftereos, Spyridon, Diller, Gerhard-Paul, Gomez-Doblas, Juan, Gorenek, Bulent, Grace, Andrew, Ho, Siew Yen, Kaski, Juan-Carlos, Kuck, Karl-Heinz, Lambiase, Pier David, Sacher, Frederic, Sarquella-Brugada, Georgia, Suwalski, Piotr, Zaza, Antonio, De Potter, Tom, Sticherling, Christian, Basso, Cristina, Bocchiardo, Mario, Budts, Werner, Dobrev, Dobromir, Gevaert, Sofie, Heidbuchel, Hein, Kanagaratnam, Prapa, Kriebel, Thomas, Lancellotti, Patrizio, Lopatin, Yury, Merkely, Béla, Paul, Thomas, Pavlović, Nikola, Potpara, Tatjana, Scherr, Daniel, Zeppenfeld, Katja, Windecker, Stephan, Aboyans, Victor, Baigent, Colin, Collet, Jean-Philippe, Dean, Veronica, Delgado, Victoria, Fitzsimons, Donna, Gale, Chris, Grobbee, Diederick, Halvorsen, Sigrun, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lewis, Basil, Merkely, Bela, Mueller, Christian, Petersen, Steffen, Petronio, Anna Sonia, Richter, Dimitrios, Roffi, Marco, Shlyakhto, Evgeny, Simpson, Iain, Sousa-Uva, Miguel, Touyz, Rhian, Amara, Walid, Grigoryan, Svetlana, Podczeck-Schweighofer, Andrea, Chasnoits, Alexandr, Vandekerckhove, Yves, Sokolovich, Sekib, Traykov, Vassil, Skoric, Bosko, Papasavvas, Elias, Kautzner, Josef, Riahi, Sam, Kampus, Priit, Parikka, Hannu, Piot, Olivier, Etsadashvili, Kakhaber, STELLBRINK, CHRISTOPH, Manolis, Antonis, Csanádi, Zoltán, Gudmundsson, Kristjan, Erwin, John, Barsheshet, Alon, De Ponti, Roberto, Abdrakhmanov, Ayan, Jashari, Haki, Lunegova, Olga, Jubele, Kristine, Refaat, Marwan, Puodziukynas, Aras, Groben, Laurent, Grosu, Aurel, Pavlovic, Nikola, Ibtissam, Fellat, Trines, Serge, Poposka, Lidija, Haugaa, Kristina, Kowalski, Oskar, Cavaco, Diogo, Dobreanu, Dan, Mikhaylov, Evgeny, Zavatta, Marco, Nebojša, Mujović, Hlivak, Peter, Ferreira-Gonzalez, Ignacio, Juhlin, Tord, Reichlin, Tobias, Haouala, Habib, Akgun, Taylan, Gupta, Dhiraj, IHU-LIRYC, and Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux]

Subjects
Tachycardia, pre-excitation, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, focal, [SDV]Life Sciences [q-bio], Cardiology, Guidelines, 030204 cardiovascular system & hematology, tachycardia, arrhythmia, ablation, atrioventricular, flutter, junctional, macro–re-entrant, nodal, re-entrant, supraventricular, Electrocardiography, 03 medical and health sciences, 0302 clinical medicine, Tachycardia, Supraventricular, medicine, Humans, cardiovascular diseases, ComputingMilieux_MISCELLANEOUS, reproductive and urinary physiology, Task force, business.industry, Arrhythmias, Cardiac, 030229 sport sciences, medicine.disease, 3. Good health, EBSTEIN ANOMALY, embryonic structures, Emergency medicine, Catheter Ablation, cardiovascular system, Re entrant, Supraventricular tachycardia, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

2019 ESC Guidelines for the management of patients with supraventricular tachycardia : The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC): Developed in collaboration with the Association for European Paediatric and Congenital Cardiology (AEPC)

Published
2019

7. Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis

Author

Lorenzen, Johan M., Schauerte, Celina, Hübner, Anika, Kölling, Malte, Martino, Filippo, Scherf, Kristian, Batkai, Sandor, Zimmer, Karina, Foinquinos, Ariana, Kaucsar, Tamas, Fiedler, Jan, Kumarswamy, Regalla, Bang, Claudia, Hartmann, Dorothee, Gupta, Shashi K., Kielstein, Jan, Jungmann, Andreas, Katus, Hugo A., Weidemann, Frank, Müller, Oliver J., Haller, Hermann, and Thum, Thomas

Published
2015
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9. Silencing of CCR2 in myocarditis

Author

Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J., Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I., Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A., Lin, Charles, Libby, Peter, Swirski, Filip K., Anderson, Daniel G., Weissleder, Ralph, and Nahrendorf, Matthias

Published
2015
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10. Atlas of the clinical genetics of human dilated cardiomyopathy

Author

Haas, Jan, Frese, Karen S., Peil, Barbara, Kloos, Wanda, Keller, Andreas, Nietsch, Rouven, Feng, Zhu, Müller, Sabine, Kayvanpour, Elham, Vogel, Britta, Sedaghat-Hamedani, Farbod, Lim, Wei-Keat, Zhao, Xiaohong, Fradkin, Dmitriy, Köhler, Doreen, Fischer, Simon, Franke, Jennifer, Marquart, Sabine, Barb, Ioana, Li, Daniel Tian, Amr, Ali, Ehlermann, Philipp, Mereles, Derliz, Weis, Tanja, Hassel, Sarah, Kremer, Andreas, King, Vanessa, Wirsz, Emil, Isnard, Richard, Komajda, Michel, Serio, Alessandra, Grasso, Maurizia, Syrris, Petros, Wicks, Eleanor, Plagnol, Vincent, Lopes, Luis, Gadgaard, Tenna, Eiskjær, Hans, Jørgensen, Mads, Garcia-Giustiniani, Diego, Ortiz-Genga, Martin, Crespo-Leiro, Maria G., Deprez, Rondal H. Lekanne Dit, Christiaans, Imke, van Rijsingen, Ingrid A., Wilde, Arthur A., Waldenstrom, Anders, Bolognesi, Martino, Bellazzi, Riccardo, Mörner, Stellan, Bermejo, Justo Lorenzo, Monserrat, Lorenzo, Villard, Eric, Mogensen, Jens, Pinto, Yigal M., Charron, Philippe, Elliott, Perry, Arbustini, Eloisa, Katus, Hugo A., and Meder, Benjamin

Published
2015
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11. Early discharge using single cardiac troponin and copeptin testing in patients with suspected acute coronary syndrome (ACS): a randomized, controlled clinical process study

Author

Möckel, Martin, Searle, Julia, Hamm, Christian, Slagman, Anna, Blankenberg, Stefan, Huber, Kurt, Katus, Hugo, Liebetrau, Christoph, Müller, Christian, Muller, Reinhold, Peitsmeyer, Philipp, von Recum, Johannes, Tajsic, Milos, Vollert, Jörn O., and Giannitsis, Evangelos

Published
2015
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12. 2020 ESC guidelines on sports cardiology and exercise in patients with cardiovascular disease : The Task Force on sports cardiology and exercise in patients with cardiovascular disease of the European Society of Cardiology (ESC)

Author

Pelliccia, Antonio, Sharma, Sanjay, Gati, Sabiha, Bäck, Maria, Börjesson, Mats, Caselli, Stefano, Collet, Jean-Philippe, Corrado, Domenico, Drezner, Jonathan A., Halle, Martin, Hansen, Dominique, Heidbüchel, Hein, Myers, Jonathan, Niebauer, Josef, Papadakis, Michael, Piepoli, Massimo Francesco, Prescott, Eva, Roos-Hesselink, Jolien W., Graham Stuart, A., Taylor, Rod S., Thompson, Paul D., Tiberi, Monica, Vanhees, Luc, Wilhelm, Matthias, Guazzi, Marco, La Gerche, André, Aboyans, Victor, Adami, Paolo Emilio, Backs, Johannes, Baggish, Aaron, Basso, Cristina, Biffi, Alessandro, Bucciarelli-Ducci, Chiara, Camm, A. John, Claessen, Guido, Delgado, Victoria, Elliott, Perry M., Galderisi, Maurizio, Gale, Chris P., Gray, Belinda, Haugaa, Kristina Hermann, Iung, Bernard, Katus, Hugo A., Keren, Andre, Leclercq, Christophe, Lewis, Basil S., Mont, Lluis, Mueller, Christian, Petersen, Steffen E., Petronio, Anna Sonia, Roffi, Marco, Savonen, Kai, Serratosa, Luis, Shlyakhto, Evgeny, Simpson, Iain A., Sitges, Marta, Solberg, Erik Ekker, Sousa-Uva, Miguel, van Craenenbroeck, Emeline, Van De Heyning, Caroline, Wijns, William, and ESC Scientific Document Group

Subjects
Human medicine
Published
2021

13. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

Author

Ibanez, Borja, James, Stefan, Agewall, Stefan, Antunes, Manuel J., Bucciarelli-Ducci, Chiara, Bueno, Hector, Caforio, Alida L. P., Crea, Filippo, Goudevenos, John A., Halvorsen, Sigrun, Hindricks, Gerhard, Kastrati, Adnan, Lenzen, Mattie J., Prescott, Eva, Roffi, Marco, Valgimigli, Marco, Varenhorst, Christoph, Vranckx, Pascal, Widimský, Petr, Baumbach, Andreas, Bugiardini, Raffaele, Coman, Ioan Mircea, Delgado, Victoria, Fitzsimons, Donna, Gaemperli, Oliver, Gershlick, Anthony H., Gielen, Stephan, Harjola, Veli-Pekka, Katus, Hugo A., Knuuti, Juhani, Kolh, Philippe, Leclercq, Christophe, Lip, Gregory Y. H., Morais, Joao, Neskovic, Aleksandar N., Neumann, Franz-Josef, Niessner, Alexander, Piepoli, Massimo Francesco, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A, Steg, Ph Gabriel, Terkelsen, Christian Juhl, Thygesen, Kristian, Windecker, Stephan, Zamorano, Jose Luis, Zeymer, Uwe, Ibanez, Borja, James, Stefan, Agewall, Stefan, Antunes, Manuel J., Bucciarelli-Ducci, Chiara, Bueno, Hector, Caforio, Alida L. P., Crea, Filippo, Goudevenos, John A., Halvorsen, Sigrun, Hindricks, Gerhard, Kastrati, Adnan, Lenzen, Mattie J., Prescott, Eva, Roffi, Marco, Valgimigli, Marco, Varenhorst, Christoph, Vranckx, Pascal, Widimskã½, Petr, Baumbach, Andrea, Bugiardini, Raffaele, Coman, Ioan Mircea, Delgado, Victoria, Fitzsimons, Donna, Gaemperli, Oliver, Gershlick, Anthony H., Gielen, Stephan, Harjola, Veli-Pekka, Katus, Hugo A., Knuuti, Juhani, Kolh, Philippe, Leclercq, Christophe, Lip, Gregory Y. H., Morais, Joao, Neskovic, Aleksandar N., Neumann, Franz-Josef, Niessner, Alexander, Piepoli, Massimo Francesco, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A, Steg, Ph Gabriel, Terkelsen, Christian Juhl, Thygesen, Kristian, Windecker, Stephan, Zamorano, Jose Lui, and Zeymer, Uwe

Subjects
Quality indicator, medicine.medical_treatment, Quality indicators, Guideline, ST-segment elevation, 030204 cardiovascular system & hematology, 0302 clinical medicine, ST segment, 030212 general & internal medicine, Myocardial infarction, reproductive and urinary physiology, Emergency medical system, Evidence, Risk assessment, MINOCA, Ischaemic heart disease, Fibrinolysis, Secondary prevention, Primary percutaneous coronary intervention, Reperfusion therapy, Antithrombotics, embryonic structures, Cardiology, Acute coronary syndrome, biological phenomena, cell phenomena, and immunity, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Acute myocardial infarction, Acute coronary syndromes, Guidelines, Antithrombotic therapy, 03 medical and health sciences, Antithrombotic, Internal medicine, medicine, Fibrinolysi, In patient, cardiovascular diseases, urogenital system, Task force, business.industry, medicine.disease, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, business
Abstract

The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their publication. The ESC is not responsible in the event of any contradiction, discrepancy and/or ambiguity between the ESC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies. Health professionals are encouraged to take the ESC Guidelines fully into account when exercising their clinical judgment, as well as in the determination and the implementation of preventive, diagnostic or therapeutic medical strategies; however, the ESC Guidelines do not override, in any way whatsoever, the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient's health condition and in consultation with that patient and, where appropriate and/or necessary, the patient's caregiver. Nor do the ESC Guidelines exempt health professionals from taking into full and careful consideration the relevant official updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient's case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations. It is also the health professional's responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.

Published
2017

14. 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)

Author

Aboyans, Victor, Ricco, Jean-Baptiste, Bartelink, Marie-Louise E. L., Björck, Martin, Brodmann, Marianne, Cohnert, Tina, Collet, Jean-Philippe, Czerny, Martin, De Carlo, Marco, Debus, Sebastian, Espinola-Klein, Christine, Kahan, Thomas, Kownator, Serge, Mazzolai, Lucia, Naylor, A Ross, Roffi, Marco, Röther, Joachim, Sprynger, Muriel, Tendera, Michal, Tepe, Gunnar, Venermo, Maarit, Vlachopoulos, Charalambos, Desormais, Ileana, Widimsky, Petr, Kolh, Philippe, Agewall, Stefan, Bueno, Héctor, Coca, Antonio, De Borst, Gert J., Delgado, Victoria, Dick, Florian, Erol, Cetin, Ferrini, Marc, Kakkos, Stavros, Katus, Hugo A., Knuuti, Juhani, Lindholt, Jes, Mattle, Heinrich, Pieniazek, Piotr, Piepoli, Massimo Francesco, Scheinert, Dierk, Sievert, Horst, Simpson, Iain, Sulzenko, Jakub, Tamargo, Juan, Tokgozoglu, Lale, Torbicki, Adam, Tsakountakis, Nikolaos, Tuñón, José, De Ceniga, Melina Vega, Windecker, Stephan, Zamorano, Jose Luis, Barbato, Emanuele, Coman, Ioan Mircea, Dean, Veronica, Fitzsimons, Donna, Gaemperli, Oliver, Hindricks, Gerhard, Iung, Bernard, Juni, Peter, Lancellotti, Patrizio, Leclercq, Christophe, McDonagh, Theresa, Ponikowski, Piotr, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A., Zelveian, Parounak H., Haumer, Markus, Isachkin, Dzmitry, De Backer, Tine, Dilic, Mirza, Petrov, Ivo, Kirhmajer, Majda Vrkic, Karetova, Debora, Prescott, Eva, Soliman, Hamdy, Paapstel, Ants, Makinen, Kimmo, Tosev, Slavco, Messas, Emmanuel, Pagava, Zurab, Müller, Oliver J., Naka, Katerina K., Járai, Zoltán, Gudjonsson, Thorbjorn, Jonas, Michael, Novo, Salvatore, Ibrahimi, Pranvera, Lunegova, Olga, Dzerve, Vilnis, Misonis, Nerijus, Beissel, Jean, Pllaha, Elton, Taberkant, Mustapha, Bakken, Torbjørn, Teles, Rui, Lighezan, Daniel, Konradi, Alexandra, Zavatta, Marco, Madaric, Juraj, Fras, Zlatko, Melchor, Lorenzo Silva, Näslund, Ulf, Amann-Vesti, Beatrice, Obiekezie, Agu, Aboyans, Victor, Ricco, Jean-Baptiste, Bartelink, Marie-Louise E.L., Björck, Martin, Brodmann, Marianne, Cohnert, Tina, Collet, Jean-Philippe, Czerny, Martin, De Carlo, Marco, Debus, Sebastian, Espinola-Klein, Christine, Kahan, Thoma, Kownator, Serge, Mazzolai, Lucia, Naylor, A Ro, Roffi, Marco, Röther, Joachim, Sprynger, Muriel, Tendera, Michal, Tepe, Gunnar, Venermo, Maarit, Vlachopoulos, Charalambo, Desormais, Ileana, Widimsky, Petr, Kolh, Philippe, Agewall, Stefan, Bueno, Héctor, Coca, Antonio, De Borst, Gert J., Delgado, Victoria, Dick, Florian, Erol, Cetin, Ferrini, Marc, Kakkos, Stavro, Katus, Hugo A., Knuuti, Juhani, Lindholt, Je, Mattle, Heinrich, Pieniazek, Piotr, Piepoli, Massimo Francesco, Scheinert, Dierk, Sievert, Horst, Simpson, Iain, Sulzenko, Jakub, Tamargo, Juan, Tokgozoglu, Lale, Torbicki, Adam, Tsakountakis, Nikolao, Tuñón, José, De Ceniga, Melina Vega, Windecker, Stephan, Zamorano, Jose Lui, Barbato, Emanuele, Coman, Ioan Mircea, Dean, Veronica, Fitzsimons, Donna, Gaemperli, Oliver, Hindricks, Gerhard, Iung, Bernard, Juni, Peter, Lancellotti, Patrizio, Leclercq, Christophe, McDonagh, Theresa, Ponikowski, Piotr, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A., Zelveian, Parounak H., Haumer, Marku, Isachkin, Dzmitry, De Backer, Tine, Dilic, Mirza, Petrov, Ivo, Kirhmajer, Majda Vrkic, Karetova, Debora, Prescott, Eva, Soliman, Hamdy, Paapstel, Ant, Makinen, Kimmo, Tosev, Slavco, Messas, Emmanuel, Pagava, Zurab, Müller, Oliver J., Naka, Katerina K., Járai, Zoltán, Gudjonsson, Thorbjorn, Jonas, Michael, Novo, Salvatore, Ibrahimi, Pranvera, Lunegova, Olga, Dzerve, Vilni, Misonis, Neriju, Beissel, Jean, Pllaha, Elton, Taberkant, Mustapha, Bakken, Torbjørn, Teles, Rui, Lighezan, Daniel, Konradi, Alexandra, Zavatta, Marco, Madaric, Juraj, Fras, Zlatko, Melchor, Lorenzo Silva, Näslund, Ulf, Amann-Vesti, Beatrice, and Obiekezie, Agu

Subjects
medicine.medical_specialty, Carotid artery disease, business.industry, Atherosclerotic disease, Upper extremity artery disease, Guideline, 030204 cardiovascular system & hematology, Vascular surgery, Lower extremity artery disease, Multisite artery disease, Peripheral Arterial Diseases, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Renal artery disease, Internal medicine, Peripheral arterial disease, medicine, Cardiology, Mesenteric artery disease, 030212 general & internal medicine, Vertebral artery disease, Cardiology and Cardiovascular Medicine, business
Abstract

2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) : Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries

Published
2017

15. The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial

Author

Husted, Steen, James, Stefan K., Bach, Richard G., Becker, Richard C., Budaj, Andrzej, Heras, Magda, Himmelmann, Anders, Horrow, Jay, Katus, Hugo A., Lassila, Riita, Morais, Joao, Nicolau, José C., Steg, Ph. Gabriel, Storey, Robert F., Wojdyla, Daniel, and Wallentin, Lars

Published
2014
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16. A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy

Author

Meder, Benjamin, Rühle, Frank, Weis, Tanja, Homuth, Georg, Keller, Andreas, Franke, Jennifer, Peil, Barbara, Lorenzo Bermejo, Justo, Frese, Karen, Huge, Andreas, Witten, Anika, Vogel, Britta, Haas, Jan, Völker, Uwe, Ernst, Florian, Teumer, Alexander, Ehlermann, Philipp, Zugck, Christian, Friedrichs, Frauke, Kroemer, Heyo, Dörr, Marcus, Hoffmann, Wolfgang, Maisch, Bernhard, Pankuweit, Sabine, Ruppert, Volker, Scheffold, Thomas, Kühl, Uwe, Schultheiss, Hans-Peter, Kreutz, Reinhold, Ertl, Georg, Angermann, Christiane, Charron, Philippe, Villard, Eric, Gary, Françoise, Isnard, Richard, Komajda, Michel, Lutz, Matthias, Meitinger, Thomas, Sinner, Moritz F., Wichmann, H.-Erich, Krawczak, Michael, Ivandic, Boris, Weichenhan, Dieter, Gelbrich, Goetz, El-Mokhtari, Nour-Eddine, Schreiber, Stefan, Felix, Stephan B., Hasenfu, Gerd, Pfeufer, Arne, Hübner, Norbert, Kääb, Stefan, Arbustini, Eloisa, Rottbauer, Wolfgang, Frey, Norbert, Stoll, Monika, and Katus, Hugo A.

Published
2014
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19. Myocardial injury in severe COVID-19 infection

Author

Jaffe, Allan S, Cleland, John G F, and Katus, Hugo A

Subjects
2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), biology, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Fast Track Clinical Research, medicine.disease_cause, biology.organism_classification, Virology, R1, Editorial, Pandemic, medicine, business, Cardiology and Cardiovascular Medicine, Coronavirus Infections, Betacoronavirus, Coronavirus
Abstract

No abstract available.

Published
2020
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24. Third universal definition of myocardial infarction

Author

Thygesen, Kristian, Alpert, Joseph S., Jaffe, Allan S., Simoons, Maarten L., Chaitman, Bernard R., White, Harvey D., Thygesen, Kristian, Alpert, Joseph S., White, Harvey D., Jaffe, Allan S., Katus, Hugo A., Apple, Fred S., Lindahl, Bertil, Morrow, David A., Chaitman, Bernard R., Clemmensen, Peter M., Johanson, Per, Hod, Hanoch, Underwood, Richard, Bax, Jeroen J., Bonow, Robert O., Pinto, Fausto, Gibbons, Raymond J., Fox, Keith A., Atar, Dan, Newby, L. Kristin, Galvani, Marcello, Hamm, Christian W., Uretsky, Barry F., Gabriel Steg, Ph., Wijns, William, Bassand, Jean-Pierre, Menasché, Phillippe, Ravkilde, Jan, Ohman, E. Magnus, Antman, Elliott M., Wallentin, Lars C., Armstrong, Paul W., Simoons, Maarten L., Januzzi, James L., Nieminen, Markku S., Gheorghiade, Mihai, Filippatos, Gerasimos, Luepker, Russell V., Fortmann, Stephen P., Rosamond, Wayne D., Levy, Dan, Wood, David, Smith, Sidney C., Hu, Dayi, Lopez-Sendon, José-Luis, Robertson, Rose Marie, Weaver, Douglas, Tendera, Michal, Bove, Alfred A., Parkhomenko, Alexander N., Vasilieva, Elena J., Mendis, Shanti, Bax, Jeroen J., Baumgartner, Helmut, Ceconi, Claudio, Dean, Veronica, Deaton, Christi, Fagard, Robert, Funck-Brentano, Christian, Hasdai, David, Hoes, Arno, Kirchhof, Paulus, Knuuti, Juhani, Kolh, Philippe, McDonagh, Theresa, Moulin, Cyril, Popescu, Bogdan A., Reiner, Željko, Sechtem, Udo, Sirnes, Per Anton, Tendera, Michal, Torbicki, Adam, Vahanian, Alec, Windecker, Stephan, Morais, Joao, Aguiar, Carlos, Almahmeed, Wael, Arnar, David O., Barili, Fabio, Bloch, Kenneth D., Bolger, Ann F., Bøtker, Hans Erik, Bozkurt, Biykem, Bugiardini, Raffaele, Cannon, Christopher, de Lemos, James, Eberli, Franz R., Escobar, Edgardo, Hlatky, Mark, James, Stefan, Kern, Karl B., Moliterno, David J., Mueller, Christian, Neskovic, Aleksandar N., Pieske, Burkert Mathias, Schulman, Steven P., Storey, Robert F., Taubert, Kathryn A., Vranckx, Pascal, and Wagner, Daniel R.

Published
2012
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25. European Society of Cardiology: cardiovascular disease statistics 2021.

Author

Group), Adam Timmis (Chair Writing, Vardas, Panos, Townsend, Nick, Torbica, Aleksandra, Katus, Hugo, Smedt, Delphine De, Gale, Chris P., Maggioni, Aldo P., Petersen, Steffen E., Huculeci, Radu, Kazakiewicz, Dzianis, Rubio, Victor de Benito, Ignatiuk, Barbara, Raisi-Estabragh, Zahra, Pawlak, Agnieszka, Karagiannidis, Efstratios, Treskes, Roderick, Gaita, Dan, Beltrame, John F., and McConnachie, Alex

Subjects
CARDIOVASCULAR diseases, MORTALITY, CARDIAC surgery, INFRASTRUCTURE (Economics)
Abstract

Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) statistics for the 57 ESC member countries. Methods and results Statistics pertaining to 2019, or the latest available year, are presented. Data sources include the World Health Organization, the Institute for Health Metrics and Evaluation, the World Bank, and novel ESC sponsored data on human and capital infrastructure and cardiovascular healthcare delivery. New material in this report includes sociodemographic and environmental determinants of CVD, rheumatic heart disease, out-of-hospital cardiac arrest, left-sided valvular heart disease, the advocacy potential of these CVD statistics, and progress towards World Health Organization (WHO) 2025 targets for non-communicable diseases. Salient observations in this report: (i) Females born in ESC member countries in 2018 are expected to live 80.8 years and males 74.8 years. Life expectancy is longer in high income (81.6 years) compared with middle-income (74.2 years) countries. (ii) In 2018, high-income countries spent, on average, four times more on healthcare than middle-income countries. (iii) The median PM2.5 concentrations in 2019 were over twice as high in middle-income ESC member countries compared with high-income countries and exceeded the EU air quality standard in 14 countries, all middle-income. (iv) In 2016, more than one in five adults across the ESC member countries were obese with similar prevalence in high and low-income countries. The prevalence of obesity has more than doubled over the past 35 years. (v) The burden of CVD falls hardest on middle-income ESC member countries where estimated incidence rates are ∼30% higher compared with high-income countries. This is reflected in disability-adjusted life years due to CVD which are nearly four times as high in middle-income compared with high-income countries. (vi) The incidence of calcific aortic valve disease has increased seven-fold during the last 30 years, with age-standardized rates four times as high in high-income compared with middle-income countries. (vii) Although the total number of CVD deaths across all countries far exceeds the number of cancer deaths for both sexes, there are 15 ESC member countries in which cancer accounts for more deaths than CVD in males and five-member countries in which cancer accounts for more deaths than CVD in females. (viii) The under-resourced status of middle-income countries is associated with a severe procedural deficit compared with high-income countries in terms of coronary intervention, ablation procedures, device implantation, and cardiac surgical procedures. Conclusion Risk factors and unhealthy behaviours are potentially reversible, and this provides a huge opportunity to address the health inequalities across ESC member countries that are highlighted in this report. It seems clear, however, that efforts to seize this opportunity are falling short and present evidence suggests that most of the WHO NCD targets for 2025 are unlikely to be met across ESC member countries. [ABSTRACT FROM AUTHOR]

Published
2022
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26. How to use high-sensitivity cardiac troponins in acute cardiac care†

Author

Thygesen, Kristian, Mair, Johannes, Giannitsis, Evangelos, Mueller, Christian, Lindahl, Bertil, Blankenberg, Stefan, Huber, Kurt, Plebani, Mario, Biasucci, Luigi M., Tubaro, Marco, Collinson, Paul, Venge, Per, Hasin, Yonathan, Galvani, Marcello, Koenig, Wolfgang, Hamm, Christian, Alpert, Joseph S., Katus, Hugo, and Jaffe, Allan S.

Published
2012
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27. Recommendations for the use of natriuretic peptides in acute cardiac care†: A position statement from the Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care

Author

Thygesen, Kristian, Mair, Johannes, Mueller, Christian, Huber, Kurt, Weber, Michael, Plebani, Mario, Hasin, Yonathan, Biasucci, Luigi M., Giannitsis, Evangelos, Lindahl, Bertil, Koenig, Wolfgang, Tubaro, Marco, Collinson, Paul, Katus, Hugo, Galvani, Marcello, Venge, Per, Alpert, Joseph S., Hamm, Christian, and Jaffe, Allan S.

Published
2012
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30. Coexistence and outcome of coronary artery disease in Takotsubo syndrome

Author

Napp, L Christian, primary, Cammann, Victoria L, additional, Jaguszewski, Milosz, additional, Szawan, Konrad A, additional, Wischnewsky, Manfred, additional, Gili, Sebastiano, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, D’Ascenzo, Fabrizio, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Sorici-Barb, Ioana, additional, Noutsias, Michel, additional, Burgdorf, Christof, additional, Koenig, Wolfgang, additional, Kherad, Behrouz, additional, Sarcon, Annahita, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Arroja, Jose D, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Imori, Yoichi, additional, Kato, Ken, additional, Kobayashi, Yoshio, additional, Opolski, Grzegorz, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Dichtl, Wolfgang, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Horowitz, John D, additional, Polednikova, Karolina, additional, Tousek, Petr, additional, Widimský, Petr, additional, Winchester, David E, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Di Mario, Carlo, additional, Prasad, Abhiram, additional, Rihal, Charanjit S, additional, Schulze, P Christian, additional, Bianco, Matteo, additional, Crea, Filippo, additional, Borggrefe, Martin, additional, Maier, Lars S, additional, Pinto, Fausto J, additional, Braun-Dullaeus, Ruediger C, additional, Rottbauer, Wolfgang, additional, Katus, Hugo A, additional, Hasenfuß, Gerd, additional, Tschöpe, Carsten, additional, Pieske, Burkert M, additional, Thiele, Holger, additional, Schunkert, Heribert, additional, Böhm, Michael, additional, Felix, Stephan B, additional, Münzel, Thomas, additional, Bax, Jeroen J, additional, Bauersachs, Johann, additional, Braunwald, Eugene, additional, Lüscher, Thomas F, additional, Ruschitzka, Frank, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2020
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33. Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction

Author

Kahles, Florian, primary, Rückbeil, Marcia V, additional, Mertens, Robert W, additional, Foldenauer, Ann C, additional, Arrivas, Maria C, additional, Moellmann, Julia, additional, Lebherz, Corinna, additional, Biener, Moritz, additional, Giannitsis, Evangelos, additional, Katus, Hugo A, additional, Marx, Nikolaus, additional, and Lehrke, Michael, additional

Published
2019
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37. †Universal definition of myocardial infarction: Kristian Thygesen, Joseph S. Alpert and Harvey D. White on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction

Author

Thygesen, Kristian, Alpert, Joseph S., White, Harvey D., Jaffe, Allan S., Apple, Fred S., Galvani, Marcello, Katus, Hugo A., Newby, L. Kristin, Ravkilde, Jan, Chaitman, Bernard, Clemmensen, Peter M., Dellborg, Mikael, Hod, Hanoch, Porela, Pekka, Underwood, Richard, Bax, Jeroen J., Beller, George A., Bonow, Robert, Van Der Wall, Ernst E., Bassand, Jean-Pierre, Wijns, William, Ferguson, T. Bruce, Steg, Philippe G., Uretsky, Barry F., Williams, David O., Armstrong, Paul W., Antman, Elliott M., Fox, Keith A., Hamm, Christian W., Ohman, E. Magnus, Simoons, Maarten L., Poole-Wilson, Philip A., Gurfinkel, Enrique P., Lopez-Sendon, José-Luis, Pais, Prem, Mendis, Shanti, Zhu, Jun-Ren, Wallentin, Lars C., Fernández-Avilés, Francisco, Fox, Kim M., Parkhomenko, Alexander N., Priori, Silvia G., Tendera, Michal, Voipio-Pulkki, Liisa-Maria, Vahanian, Alec, Camm, A. John, De Caterina, Raffaele, Dean, Veronica, Dickstein, Kenneth, Filippatos, Gerasimos, Funck-Brentano, Christian, Hellemans, Irene, Kristensen, Steen Dalby, McGregor, Keith, Sechtem, Udo, Silber, Sigmund, Widimsky, Petr, Zamorano, José Luis, Morais, Joao, Brener, Sorin, Harrington, Robert, Morrow, David, Lim, Michael, Martinez-Rios, Marco A., Steinhubl, Steve, Levine, Glen N., Gibler, W. Brian, Goff, David, Tubaro, Marco, Dudek, Darek, and Al-Attar, Nawwar

Published
2007

41. Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry

Author

Gili, Sebastiano, primary, Cammann, Victoria L, additional, Schlossbauer, Susanne A, additional, Kato, Ken, additional, D’Ascenzo, Fabrizio, additional, Di Vece, Davide, additional, Jurisic, Stjepan, additional, Micek, Jozef, additional, Obeid, Slayman, additional, Bacchi, Beatrice, additional, Szawan, Konrad A, additional, Famos, Flurina, additional, Sarcon, Annahita, additional, Levinson, Rena, additional, Ding, Katharina J, additional, Seifert, Burkhardt, additional, Lenoir, Olivia, additional, Bossone, Eduardo, additional, Citro, Rodolfo, additional, Franke, Jennifer, additional, Napp, L Christian, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Münzel, Thomas, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Katus, Hugo A, additional, Burgdorf, Christof, additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Tschöpe, Carsten, additional, Pieske, Burkert M, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Hasenfuß, Gerd, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Rottbauer, Wolfgang, additional, Said, Samir M, additional, Braun-Dullaeus, Ruediger C, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Opolski, Grzegorz, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Crea, Filippo, additional, Dichtl, Wolfgang, additional, Empen, Klaus, additional, Felix, Stephan B, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Borggrefe, Martin, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Horowitz, John D, additional, Kozel, Martin, additional, Tousek, Petr, additional, Widimský, Petr, additional, Winchester, David E, additional, Ukena, Christian, additional, Gaita, Fiorenzo, additional, Di Mario, Carlo, additional, Wischnewsky, Manfred B, additional, Bax, Jeroen J, additional, Prasad, Abhiram, additional, Böhm, Michael, additional, Ruschitzka, Frank, additional, Lüscher, Thomas F, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2019
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42. Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY)

Author

Bekeredjian, Raffi, primary, Szabo, Gabor, additional, Balaban, Ümniye, additional, Bleiziffer, Sabine, additional, Bauer, Timm, additional, Ensminger, Stephan, additional, Frerker, Christian, additional, Herrmann, Eva, additional, Beyersdorf, Friedhelm, additional, Hamm, Christian, additional, Beckmann, Andreas, additional, Möllmann, Helge, additional, Karck, Matthias, additional, Katus, Hugo A, additional, and Walther, Thomas, additional

Published
2018
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43. Glucagon-like peptide 1 levels predict cardiovascular risk in patients with acute myocardial infarction.

Author

Kahles, Florian, Rückbeil, Marcia V, Mertens, Robert W, Foldenauer, Ann C, Arrivas, Maria C, Moellmann, Julia, Lebherz, Corinna, Biener, Moritz, Giannitsis, Evangelos, Katus, Hugo A, Marx, Nikolaus, and Lehrke, Michael

Abstract

Aims Glucagon-like peptide 1 (GLP-1) is a gut incretin hormone inducing post-prandial insulin secretion. Glucagon-like peptide 1 levels were recently found to be increased in patients with acute myocardial infarction. Glucagon-like peptide 1 receptor agonists improve cardiovascular outcomes in patients with diabetes. The aim of this study was to assess the predictive capacity of GLP-1 serum levels for cardiovascular outcome in patients with myocardial infarction. Methods and results In 918 patients presenting with myocardial infarction [321 ST-segment elevation myocardial infarction and 597 non-ST-segment elevation myocardial infarction (NSTEMI)] total GLP-1, N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels and the Global Registry of Acute Coronary Events (GRACE) score were assessed at time of hospital admission. The primary composite outcome of the study was the first occurrence of cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke. Kaplan–Meier survival plots and univariable Cox regression analyses found GLP-1 to be associated with adverse outcome [hazard ratio (HR) of logarithmized GLP-1 values: 6.29, 95% confidence interval (CI): 2.67–14.81; P < 0.0001]. After further adjustment for age, sex, family history of cardiovascular disease, smoking, diabetes, hypertension, hypercholesterinaemia, glomerular filtration rate (GFR) CKD-EPI, hs-CRP, hs-Troponin T, and NT-proBNP levels the HR remained significant at 10.98 (95% CI: 2.63–45.90; P  = 0.0010). Time-dependent receiver operating characteristic curve analyses illustrated that GLP-1 levels are a strong indicator for early events. For events up to 30 days after admission, GLP-1 proved to be superior to other biomarkers including hs-Troponin T, GFR CKD-EPI, hs-CRP, and NT-proBNP. Adjustment of the GRACE risk estimate by addition of GLP-1 increased the area under the receiver operating characteristic curve over time in NSTEMI patients. Conclusion In patients hospitalized for myocardial infarction, GLP-1 levels are associated with cardiovascular events. [ABSTRACT FROM AUTHOR]

Published
2020
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46. Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy

Author

Sedaghat-Hamedani, Farbod, primary, Haas, Jan, additional, Zhu, Feng, additional, Geier, Christian, additional, Kayvanpour, Elham, additional, Liss, Martin, additional, Lai, Alan, additional, Frese, Karen, additional, Pribe-Wolferts, Regina, additional, Amr, Ali, additional, Li, Daniel Tian, additional, Samani, Omid Shirvani, additional, Carstensen, Avisha, additional, Bordalo, Diana Martins, additional, Müller, Marion, additional, Fischer, Christine, additional, Shao, Jing, additional, Wang, Jing, additional, Nie, Ming, additional, Yuan, Li, additional, Haßfeld, Sabine, additional, Schwartz, Christine, additional, Zhou, Min, additional, Zhou, Zihua, additional, Shu, Yanwen, additional, Wang, Min, additional, Huang, Kai, additional, Zeng, Qiutang, additional, Cheng, Longxian, additional, Fehlmann, Tobias, additional, Ehlermann, Philipp, additional, Keller, Andreas, additional, Dieterich, Christoph, additional, Streckfuß-Bömeke, Katrin, additional, Liao, Yuhua, additional, Gotthardt, Michael, additional, Katus, Hugo A, additional, and Meder, Benjamin, additional

Published
2017
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47. Early diagnosis of acute coronary syndrome

Author

Katus, Hugo, primary, Ziegler, André, additional, Ekinci, Okan, additional, Giannitsis, Evangelos, additional, Stough, Wendy Gattis, additional, Achenbach, Stephan, additional, Blankenberg, Stefan, additional, Brueckmann, Martina, additional, Collinson, Paul, additional, Comaniciu, Dorin, additional, Crea, Filippo, additional, Dinh, Wilfried, additional, Ducrocq, Grégory, additional, Flachskampf, Frank A., additional, Fox, Keith A. A., additional, Friedrich, Matthias G., additional, Hebert, Kathy A., additional, Himmelmann, Anders, additional, Hlatky, Mark, additional, Lautsch, Dominik, additional, Lindahl, Bertil, additional, Lindholm, Daniel, additional, Mills, Nicholas L., additional, Minotti, Giorgio, additional, Möckel, Martin, additional, Omland, Torbjørn, additional, and Semjonow, Véronique, additional

Published
2017
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48. Intracoronary autologous bone marrow cell transfer after myocardial infarction: the BOOST-2 randomised placebo-controlled clinical trial

Author

Wollert, Kai C, primary, Meyer, Gerd P, additional, Müller-Ehmsen, Jochen, additional, Tschöpe, Carsten, additional, Bonarjee, Vernon, additional, Larsen, Alf Inge, additional, May, Andreas E, additional, Empen, Klaus, additional, Chorianopoulos, Emmanuel, additional, Tebbe, Ulrich, additional, Waltenberger, Johannes, additional, Mahrholdt, Heiko, additional, Ritter, Benedikta, additional, Pirr, Jens, additional, Fischer, Dieter, additional, Korf-Klingebiel, Mortimer, additional, Arseniev, Lubomir, additional, Heuft, Hans-Gert, additional, Brinchmann, Jan E, additional, Messinger, Diethelm, additional, Hertenstein, Bernd, additional, Ganser, Arnold, additional, Katus, Hugo A, additional, Felix, Stephan B, additional, Gawaz, Meinrad P, additional, Dickstein, Kenneth, additional, Schultheiss, Heinz-Peter, additional, Ladage, Dennis, additional, Greulich, Simon, additional, and Bauersachs, Johann, additional

Published
2017
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49. Inverse remodelling of K2P3.1 K+channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy

Author

Schmidt, Constanze, primary, Wiedmann, Felix, additional, Zhou, Xiao-Bo, additional, Heijman, Jordi, additional, Voigt, Niels, additional, Ratte, Antonius, additional, Lang, Siegfried, additional, Kallenberger, Stefan M., additional, Campana, Chiara, additional, Weymann, Alexander, additional, De Simone, Raffaele, additional, Szabo, Gabor, additional, Ruhparwar, Arjang, additional, Kallenbach, Klaus, additional, Karck, Matthias, additional, Ehrlich, Joachim R., additional, Baczkó, István, additional, Borggrefe, Martin, additional, Ravens, Ursula, additional, Dobrev, Dobromir, additional, Katus, Hugo A., additional, and Thomas, Dierk, additional

Published
2017
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50. Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: in-hospital data and 1-year results from the German Aortic Valve Registry (GARY).

Author

Bekeredjian, Raffi, Szabo, Gabor, Balaban, Ümniye, Bleiziffer, Sabine, Bauer, Timm, Ensminger, Stephan, Frerker, Christian, Herrmann, Eva, Beyersdorf, Friedhelm, Hamm, Christian, Beckmann, Andreas, Möllmann, Helge, Karck, Matthias, Katus, Hugo A, and Walther, Thomas

Abstract

Aims Transcatheter aortic valve implantation (TAVI) has become the standard treatment for patients with severe aortic valve stenosis at high surgical risk and may be considered for patients with intermediate risk. During the last few years, an increasing number of patients with low surgical risk have been treated with TAVI. In this study, low-risk patients undergoing isolated TAVI or surgical aortic valve replacement (SAVR) were analysed using data from the German Aortic Valve Registry (GARY). Methods and results All patients with a Society of Thoracic Surgeons Score of <4% undergoing TAVI or SAVR in 2014 and 2015 were evaluated. A total of 20 549 low surgical risk patients remained for further analysis, comprising 14 487 surgical patients and 6062 TAVI patients. Since TAVI patients were significantly older and had significantly more co-morbidities, a weighted propensity score model was used to compare SAVR and TAVI patients for in-hospital, 30-day, and 1-year mortality. Transcatheter aortic valve implantation patients showed a significantly higher in-hospital and 30-day survival than SAVR patients (in hospital survival TAVI vs. SAVR: 98.5% vs. 97.3%; P  = 0.003; 30-day survival TAVI vs. SAVR: 98.1% vs. 97.1%; P  = 0.014). At 1 year, survival rates did not differ significantly (survival TAVI vs. SAVR: 90.0% vs. 91.2%; P  = 0.158). Conclusion In this first GARY analysis of low-risk patients, weighted comparison showed similar 1-year survival for TAVI and SAVR and higher in-hospital survival for TAVI patients. [ABSTRACT FROM AUTHOR]

Published
2019
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