1. Emergence of carbapenem-resistant ST131
- Author
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Sybille, Welker, Sébastien, Boutin, Thomas, Miethke, Klaus, Heeg, and Dennis, Nurjadi
- Subjects
Adult ,OXA-244 ,carbapenem resistance ,biochemical phenomena, metabolism, and nutrition ,Middle Aged ,Escherichia coli ST131 ,Young Adult ,Enterobacterales ,Carbapenems ,Germany ,Drug Resistance, Bacterial ,polycyclic compounds ,Escherichia coli ,bacteria ,Humans ,antimicrobial resistance ,Child ,Escherichia coli Infections ,Rapid Communication ,Aged - Abstract
The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.
- Published
- 2020