1. Early Outcome of Laparotomy Wounds in Pediatric Patients in TASH, Addis Ababa, Ethiopia: A Six-Months Prospective Study
- Author
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Belachew Dejene, Abay Gosaye, Hana Getachew, Nichole Starr, Fisseha Temesgen, Miliard Derbew, Woubedil Kiflu, Tihitena Negussie, and Amezene Tadesse
- Subjects
Male ,medicine.medical_specialty ,Multivariate analysis ,medicine.medical_treatment ,Global Surgery ,Logistic regression ,Pediatrics ,Risk Factors ,Laparotomy ,medicine ,Humans ,Surgical Wound Infection ,Wound dehiscence ,Prospective Studies ,Prospective cohort study ,Preschool ,Child ,Evisceration (ophthalmology) ,Pediatric ,business.industry ,SSI ,Mortality rate ,Prevention ,General Medicine ,medicine.disease ,Surgery ,Malnutrition ,Good Health and Well Being ,Child, Preschool ,Zero Hunger ,Original Article ,Patient Safety ,Ethiopia ,business - Abstract
BACKGROUND፡ Surgical Site Infection (SSI) and wound dehiscence are two early complications of laparotomy causing significant morbidity and mortality. This study was conducted to determine the prevalence and risk factors of SSI and wound dehiscence in pediatric surgical patients.METHODS: We performed a prospective observational study of all pediatric surgical patients who underwent laparotomy at Tikur Anbessa Specialized Hospital, Ethiopia, from December 2017 to May 2018. Data collected included demographics, operative indication, nutritional status, prophylactic antibiotics administration, and duration of operation. Primary outcome was SSI; secondary outcomes were hospital stay and other postoperative complications, including wound dehiscence and mortality. Data were analyzed using SPSS, Version 23. Fisher’s exact and Chi-squared tests used to report outcomes. Multivariable logistic regression was used to identify variables associated with SSI, wound dehiscence and other outcomes.RESULTS: Of 114 patients, median age was 46 months [range: 1day-13years]; 77(67.5 %) were males. Overall SSI rate was 21.05%. Nine (7.9%) developed wound dehiscence while 3(2.6%) had abdominal contents evisceration. Overall mortality rate was 2.6%. In multivariate analysis, prophylactic antibiotics administration (AOR=13.05, (p=0.006)), duration of procedure (AOR=8.62, (p=0.012)) and wound class (AOR=16.63, (p=0.034)) were independent risk factors for SSI while SSI was an independent predictor of prolonged hospital stay, >1 week (AOR=4.7, p=.003,) and of wound dehiscence (AOR=33. 96,p=0.003). Age (p=0.004) and malnutrition (p1 hour before surgery and operative time >2 hours are independent predictors of SSI.
- Published
- 2021