1. Granulocyte-colony stimulating factor-producing esophageal carcinosarcoma: a case report
- Author
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Kentaro Maejima, Hideki Bou, Takashi Tajiri, Masanori Watanabe, Satoshi Mizutani, Akira Tokunaga, and Osamu Komine
- Subjects
medicine.medical_specialty ,Pathology ,biology ,business.industry ,Gastroenterology ,Granulocyte colony-stimulating factor ,Esophageal Carcinosarcoma ,medicine.anatomical_structure ,Cardiothoracic surgery ,Surgical oncology ,medicine ,Vomiting ,biology.protein ,Immunohistochemistry ,medicine.symptom ,Antibody ,Esophagus ,business - Abstract
An 80-year-old man presented at our hospital with chest oppression and vomiting. An endoscopic examination revealed a tumor in the lower portion of the esophagus, and the patient was diagnosed as possibly having esophageal carcinosarcoma based on a histological examination of endoscopic biopsy specimens. During the initial medical examination, the patient had a high leukocyte count and a high level of serum granulocyte-colony stimulating factor (G-CSF). Moreover, immunohistochemical examination revealed cells that were positive for antibodies against G-CSF. Therefore, we diagnosed the patient as possibly having a G-CSF-producing esophageal carcinosarcoma. The patient died of tumor 4 months after the initial diagnosis.
- Published
- 2007
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