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Your search keyword '"Jones, R.L."' showing total 13 results
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13 results on '"Jones, R.L."'

5. 62P Updated overall survival and safety with ripretinib vs sunitinib in patients with advanced gastrointestinal stromal tumor previously treated with imatinib and harboring KIT exon 11 + 17/18 mutations: ctDNA analysis from INTRIGUE

Author

Blay, J-Y., primary, Jones, R.L., additional, Gelderblom, H., additional, George, S., additional, Schöffski, P., additional, von Mehren, M., additional, Zalcberg, J.R., additional, Kang, Y-K., additional, Razak, A.R. Abdul, additional, Trent, J.C., additional, Attia, S., additional, Le Cesne, A., additional, Davis, E., additional, Sprott, K., additional, Cox, P., additional, Sherman, M.L., additional, Ruiz-Soto, R., additional, Heinrich, M., additional, and Bauer, S., additional

Published
2024
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7. Novel trial designs for patients with gastrointestinal stromal tumor

Author

Serrano, C., primary, Rothschild, S., additional, Villacampa, G., additional, Heinrich, M.C., additional, George, S., additional, Blay, J.-Y., additional, Sicklick, J.K., additional, Schwartz, G.K., additional, Rastogi, S., additional, Jones, R.L., additional, Rutkowski, P., additional, Somaiah, N., additional, Navarro, V., additional, Evans, D., additional, and Trent, J.C., additional

Published
2024
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9. Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts

Author

Stacchiotti, S., Miah, A.B., Frezza, A.M., Messiou, C., Morosi, C., Caraceni, A., Antonescu, C.R., Bajpai, J., Baldini, E., Bauer, S., Biagini, R., Bielack, S., Blay, J.Y., Bonvalot, S., Boukovinas, I., Bovee, J.V.M.G., Boye, K., Brodowicz, T., Callegaro, D., De Alava, E., Deoras-Sutliff, M., Dufresne, A., Eriksson, M., Errani, C., Fedenko, A., Ferraresi, V., Ferrari, A., Fletcher, C.D.M., Garcia del Muro, X., Gelderblom, H., Gladdy, R.A., Gouin, F., Grignani, G., Gutkovich, J., Haas, R., Hindi, N., Hohenberger, P., Huang, P., Joensuu, H., Jones, R.L., Jungels, C., Kasper, B., Kawai, A., Le Cesne, A., Le Grange, F., Leithner, A., Leonard, H., Lopez Pousa, A., Martin Broto, J., Merimsky, O., Merriam, P., Miceli, R., Mir, O., Molinari, M., Montemurro, M., Oldani, G., Palmerini, E., Pantaleo, M.A., Patel, S., Piperno-Neumann, S., Raut, C.P., Ravi, V., Razak, A.R.A., Reichardt, P., Rubin, B.P., Rutkowski, P., Safwat, A.A., Sangalli, C., Sapisochin, G., Sbaraglia, M., Scheipl, S., Schöffski, P., Strauss, D., Strauss, S.J., Sundby Hall, K., Tap, W.D., Trama, A., Tweddle, A., van der Graaf, W.T.A., Van De Sande, M.A.J., Van Houdt, W., van Oortmerssen, G., Wagner, A.J., Wartenberg, M., Wood, J., Zaffaroni, N., Zimmermann, C., Casali, P.G., Dei Tos, A.P., and Gronchi, A.

Published
2021
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13. Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts

Author

Peter Reichardt, C. Zimmermann, Emanuela Palmerini, Paul H. Huang, G. Oldani, R. Biagini, Silvia Stacchiotti, Akira Kawai, H. Leonard, A. P. Dei Tos, Andrew J. Wagner, Mikael Eriksson, Alessandro Gronchi, Kjetil Boye, Peter Hohenberger, X. Garcia del Muro, C. Errani, Annalisa Trama, Andreas Leithner, Maria Abbondanza Pantaleo, Dirk C. Strauss, Christopher D.M. Fletcher, F. le Grange, W.J. van Houdt, Judith V.M.G. Bovée, Rick L. Haas, J. Gutkovich, Heikki Joensuu, J. Martin Broto, François Gouin, A.M. Frezza, Elizabeth H. Baldini, A. Le Cesne, Akmal Safwat, Armelle Dufresne, Susanne Scheipl, W.T.A. van der Graaf, Shreyaskumar Patel, J. Wood, Robin L. Jones, M. Molinari, Stefan S. Bielack, K. Sundby Hall, Jean-Yves Blay, Nadia Hindi, Sandra J. Strauss, Sylvie Bonvalot, Christina Messiou, Virginia Ferraresi, V. Ravi, E. de Álava, Aisha Miah, Piotr Rutkowski, A. Lopez Pousa, William D. Tap, Sophie Piperno-Neumann, Rosalba Miceli, Augusto Caraceni, G. van Oortmerssen, Rebecca A. Gladdy, M. Wartenberg, A. Fedenko, Giovanni Grignani, Thomas Brodowicz, Michael Montemurro, Albiruni Ryan Abdul Razak, Dario Callegaro, Claudia Sangalli, Ioannis Boukovinas, Patrick Schöffski, M. Deoras-Sutliff, Chandrajit P. Raut, Jyoti Bajpai, C. Jungels, Andrea C. Ferrari, A. Tweddle, Hans Gelderblom, Brian P. Rubin, Nadia Zaffaroni, Paolo G. Casali, Carlo Morosi, M. A. J. van de Sande, P. Merriam, O. Merimsky, Cristina R. Antonescu, G. Sapisochin, Olivier Mir, Sebastian Bauer, Marta Sbaraglia, Bernd Kasper, Stacchiotti S., Miah A.B., Frezza A.M., Messiou C., Morosi C., Caraceni A., Antonescu C.R., Bajpai J., Baldini E., Bauer S., Biagini R., Bielack S., Blay J.Y., Bonvalot S., Boukovinas I., Bovee J.V.M.G., Boye K., Brodowicz T., Callegaro D., De Alava E., Deoras-Sutliff M., Dufresne A., Eriksson M., Errani C., Fedenko A., Ferraresi V., Ferrari A., Fletcher C.D.M., Garcia del Muro X., Gelderblom H., Gladdy R.A., Gouin F., Grignani G., Gutkovich J., Haas R., Hindi N., Hohenberger P., Huang P., Joensuu H., Jones R.L., Jungels C., Kasper B., Kawai A., Le Cesne A., Le Grange F., Leithner A., Leonard H., Lopez Pousa A., Martin Broto J., Merimsky O., Merriam P., Miceli R., Mir O., Molinari M., Montemurro M., Oldani G., Palmerini E., Pantaleo M.A., Patel S., Piperno-Neumann S., Raut C.P., Ravi V., Razak A.R.A., Reichardt P., Rubin B.P., Rutkowski P., Safwat A.A., Sangalli C., Sapisochin G., Sbaraglia M., Scheipl S., Schoffski P., Strauss D., Strauss S.J., Sundby Hall K., Tap W.D., Trama A., Tweddle A., van der Graaf W.T.A., Van De Sande M.A.J., Van Houdt W., van Oortmerssen G., Wagner A.J., Wartenberg M., Wood J., Zaffaroni N., Zimmermann C., Casali P.G., Dei Tos A.P., Gronchi A., University of Helsinki, Department of Oncology, Heikki Joensuu / Principal Investigator, and HUS Comprehensive Cancer Center

Subjects
Cancer Research, sarcoma, diagnosis, Medizin, Disease, HEPATIC EPITHELIOID HEMANGIOENDOTHELIOMA, Review, Medical Oncology, Patient advocacy, RISK STRATIFICATION, 0302 clinical medicine, PROPOSAL, CLINICAL CHARACTERISTICS, Medicine, guidelines, Child, 0303 health sciences, ddc:617, treatment, VASCULAR TUMORS, LIVER-TRANSPLANTATION, 3. Good health, IMAGING FINDINGS, diagnosi, epithelioid hemangioendothelioma, Oncology, OF-THE-LITERATURE, 030220 oncology & carcinogenesis, Hemangioendothelioma, Epithelioid, Sarcoma, guideline, management, Human, Adult, medicine.medical_specialty, Consensus, 3122 Cancers, Consensu, Patient Advocacy, Malignancy, Hepatic Epithelioid Hemangioendothelioma, 03 medical and health sciences, Humans, Intensive care medicine, Epithelioid hemangioendothelioma, 030304 developmental biology, business.industry, SOFT-TISSUE, medicine.disease, Rare cancer, Vascular Tumors, SARCOMAS, business
Abstract

Epithelioid hemangioendothelioma (EHE) is an ultra-rare, translocated, vascular sarcoma. EHE clinical behavior is variable, ranging from that of a low-grade malignancy to that of a high-grade sarcoma and it is marked by a high propensity for systemic involvement. No active systemic agents are currently approved specifically for EHE, which is typically refractory to the antitumor drugs used in sarcomas. The degree of uncertainty in selecting the most appropriate therapy for EHE patients and the lack of guidelines on the clinical management of the disease make the adoption of new treatments inconsistent across the world, resulting in suboptimal outcomes for many EHE patients. To address the shortcoming, a global consensus meeting was organized in December 2020 under the umbrella of the European Society for Medical Oncology (ESMO) involving >80 experts from several disciplines from Europe, North America and Asia, together with a patient representative from the EHE Group, a global, disease-specific patient advocacy group, and Sarcoma Patient EuroNet (SPAEN). The meeting was aimed at defining, by consensus, evidence-based best practices for the optimal approach to primary and metastatic EHE. The consensus achieved during that meeting is the subject of the present publication., Highlights • This consensus paper provides key recommendations on the management of epithelioid hemangioendothelioma (EHE). • Recommendations followed a consensus meeting between experts and a representative of the EHE advocacy group and SPAEN. • Authorship includes a multidisciplinary group of experts from different institutions from Europe, North America and Asia.

Published
2021

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