51. Admission hyponatraemia as heart failure events predictor in patients with acute heart failure.
- Author
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Sarastri, Yuke, Zebua, Juang Idaman, Lubis, Puja Nastia, Zahra, Fathi, and Lubis, Anggia Chairuddin
- Subjects
HEART failure patients ,HEART failure ,WATER-electrolyte imbalances ,PROGNOSIS ,PATIENT readmissions - Abstract
Aims: Heart failure remained consistent as one of the biggest cardiovascular problems in Indonesia. Hyponatraemia is a common electrolyte disorder among patients presented with heart failure; however, the prognostic value for worsening heart failure has not been well defined. Methods and results: We studied 134 patients admitted with acute heart failure and investigated the relationship between admission serum sodium and the composite clinical outcomes of all‐cause mortality and hospitalization ambispectively with a follow‐up duration of 6 months. We also try to look for low sodium‐level impacts in several conditions. Among 134 patients, 84 patients presented with low sodium during admission, defined as a serum sodium level of <135 mEq/L, and it was associated with higher composite clinical outcome risk [odds ratio (OR), 5.9; 95% confidence interval (CI), 2.8–12.0; P < 0.001]. Moreover, hyponatraemia impacts on composite endpoints were driven by both parameters; it was independently associated with mortality (OR, 3.1; 95% CI, 1.4–6.8; P = 0.003) and rehospitalization (OR, 5.3; 95% CI, 2.4–11.7; P < 0.001). This result remained consistent in most subgroups. Conclusions: On‐admission hyponatraemia is a predictor for 6 month mortality and rehospitalization. Further work is needed to determine if correction of hyponatraemia translates into clinical benefit. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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