1. Diagnostic evaluation of drug-resistant insular epilepsy
- Author
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T. M. Alekseeva, W. A. Khachatryan, R. G. Khachatryan, and G. S. Ibatova
- Subjects
Pediatrics ,medicine.medical_specialty ,Drug resistance ,Diagnostic evaluation ,Insular cortex ,behavioral disciplines and activities ,Temporal lobe surgery ,Temporal lobe ,03 medical and health sciences ,Epilepsy ,0302 clinical medicine ,medicine ,RC346-429 ,insular epilepsy ,drug resistance ,business.industry ,temporal lobe epilepsy ,medicine.disease ,Lobe ,presurgical evaluation ,medicine.anatomical_structure ,nervous system ,Neurology ,030220 oncology & carcinogenesis ,behavior and behavior mechanisms ,Neurology. Diseases of the nervous system ,Neurology (clinical) ,business ,Insula ,psychological phenomena and processes ,030217 neurology & neurosurgery - Abstract
About 30% of patients with temporal epilepsy are resistant to antiepileptic drugs; in such cases, surgical treatment is considered to be the best option. Existence of an extra-temporal epileptogenic focus in the insula is a possible cause of seizures after temporal lobe surgery in about 20% of patients. Because of its localization, the anatomical features of the insular lobe, as well as the entire concept of insular epilepsy have not been well documented. Yet, it has been established that the seizures developing from the insular cortex can mimic the paroxysms arising from the temporal lobe. When the insula is involved in the epileptic process, resection of the insular cortex improves the outcome of surgical treatment. Rational and well-based selection of candidates for surgical treatment is of paramount importance for patients with drug-resistant epilepsy. The article presents a review of the up-to-date literature on this matter.
- Published
- 2019
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