8 results on '"Ten Have, M"'
Search Results
2. Mental disorders and the risk of adult violent and psychological victimisation: a prospective, population-based study
- Author
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Christ, C., primary, Ten Have, M., additional, de Graaf, R., additional, van Schaik, D. J. F., additional, Kikkert, M. J., additional, Dekker, J. J. M., additional, and Beekman, A. T. F., additional
- Published
- 2019
- Full Text
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3. ‘False-positive’ self-reported psychotic experiences in the general population: an investigation of outcome, predictive factors and clinical relevance
- Author
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van der Steen, Y., primary, Myin-Germeys, I., additional, van Nierop, M., additional, ten Have, M., additional, de Graaf, R., additional, van Dorsselaer, S., additional, van Os, J., additional, and van Winkel, R., additional
- Published
- 2018
- Full Text
- View/download PDF
4. ‘False-positive’ self-reported psychotic experiences in the general population: an investigation of outcome, predictive factors and clinical relevance
- Author
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van der Steen, Y., Myin-Germeys, I., van Nierop, M., ten Have, M., de Graaf, R., van Dorsselaer, S., van Os, J., and van Winkel, R.
- Abstract
Aims.Self-reported psychotic experiences (SRPE) by individuals from the general population are often unconfirmed by clinical interview and referred to as ‘false-positive’ (FP) SRPE. FP SRPE have been suggested to represent the mildest form of risk along the extended psychosis continuum. However, little is known about their (clinical) outcome and evolution over time. Aims of this study were to prospectively examine, in individuals with FP SRPE, (1) the prevalence of remission, persistence and transition to validated PE at 3-year follow-up; (2) potential baseline psychopathological and psychosocial predictors of persistence of FP SRPE and transition to validated PE; and (3) whether those with persistent FP SRPE and validated PE already differed on psychopathology and psychosocial factors at baseline. We tested the hypotheses that (i) individuals with FP SRPE would be more likely to have SRPE and validated PE at follow-up; and (ii) that FP SRPE would be predictive of lower functioning and more psychopathology and help-seeking behaviour at follow-up.Methods.Baseline (n= 6646) and 3-year follow-up (n= 5303) data of the second the Netherlands Mental Health Survey and Incidence Study (NEMESIS-2), a general population research project on prevalence, incidence, course and consequences of psychiatric disorders was used. Self-report of PE was followed by clinical interview to determine clinical validity. The presence of mood, anxiety and substance use disorders, childhood adversity, help-seeking and functioning as well as PE characteristics (number, frequency, distress and impact) were used in the analyses which included only individuals with complete data for both assessments waves (n= 4683).Results.At baseline, 454 participants had any FP SRPE; of these 372 participants had complete follow-up data available. Those with baseline FP SRPE were significantly more likely to report SRPE (OR = 3.58; 95% CI 2.38–5.40, p< 0.001) and validated PE (OR = 6.26; 95% CI 3.91–10.02, p< 0.001) at follow-up. Baseline FP SRPE also predicted the presence of mood and anxiety disorders, reduced functioning and help-seeking at follow-up. Several baseline psychopathological, psychosocial and PE characteristics were predictive for the persistence of SRPE. These factors also differentiated groups with FP SRPE or validated PE from those with remitted FP SRPE at follow-up.Conclusions.‘FP SRPE’ are not truly ‘false’ as they index risk for the development of clinically relevant psychotic symptoms, development of mood and anxiety disorders and reduced functioning. Self-reported PE, even unconfirmed, warrant ‘watchful waiting’ and follow-up over time, especially when they are reported by individuals with reduced psychosocial functioning and general psychiatric problems.
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- 2019
- Full Text
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5. Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys
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Kessler, R. C., primary, Sampson, N. A., additional, Berglund, P., additional, Gruber, M. J., additional, Al-Hamzawi, A., additional, Andrade, L., additional, Bunting, B., additional, Demyttenaere, K., additional, Florescu, S., additional, de Girolamo, G., additional, Gureje, O., additional, He, Y., additional, Hu, C., additional, Huang, Y., additional, Karam, E., additional, Kovess-Masfety, V., additional, Lee, S, additional, Levinson, D., additional, Medina Mora, M. E., additional, Moskalewicz, J., additional, Nakamura, Y., additional, Navarro-Mateu, F., additional, Browne, M. A. Oakley, additional, Piazza, M., additional, Posada-Villa, J., additional, Slade, T., additional, ten Have, M., additional, Torres, Y., additional, Vilagut, G., additional, Xavier, M., additional, Zarkov, Z., additional, Shahly, V., additional, and Wilcox, M. A., additional
- Published
- 2015
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6. The relationship between mental disorders and actual and desired subjective social status
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de Vries, Y. A., ten Have, M., de Graaf, R., van Dorsselaer, S., de Ruiter, N. M. P., and de Jonge, P.
- Abstract
AbstractAimsMental disorders are associated with lower subjective social status (SSS), but a more nuanced understanding of this relationship is needed. We examined the influence of disorder age of onset and recency on SSS and studied whether mental disorders are also associated with the discrepancy between actualand desiredSSS.MethodData are from the baseline and second wave of the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2). Mental disorders were assessed with the Composite International Diagnostic Interview (CIDI 3.0), while both actual and desired SSS were assessed with a ten-rung ladder. Linear regression was used to examine the association between mental disorders and SSS.ResultsOf 5303 participants, 2237 had a lifetime mental disorder at baseline. These participants reported significantly lower actual SSS (6.28) at follow-up than healthy participants (6.66, B= −0.38 [95% CI −0.48 to −0.27], p< 0.001) and a significantly greater actual-desired SSS discrepancy (1.14 v. 1.05 after controlling for actual SSS, B= 0.09 [0.01–0.17], p= 0.024). Lower age of onset of the first mental disorder was marginally significantly associated with lower actual SSS (B= 0.006 [0.000–0.012], p= 0.046). More recent disorders were also associated with lower actual SSS (B= 0.015 [0.005–0.026], p= 0.005), such that participants whose disorder remitted ⩾6 years before baseline were statistically indistinguishable from healthy participants.ConclusionsLifetime mental disorders are associated with lower actual SSS and a slightly greater discrepancy between actual and desired SSS. However, people with mental disorders in (long-term) remission have a similar social status as healthy participants.
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- 2020
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7. Alcohol use as a predictor of the course of major depressive disorder: a prospective population-based study.
- Author
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Schouten MJE, Ten Have M, Tuithof M, de Graaf R, Dekker JJM, Goudriaan AE, and Blankers M
- Subjects
- Adult, Humans, Male, Female, Middle Aged, Prospective Studies, Alcohol Drinking epidemiology, Cohort Studies, Depressive Disorder, Major psychology, Alcoholism epidemiology, Alcoholism psychology
- Abstract
Aims: There are indications that problematic alcohol use may negatively impact the course of major depressive disorder (MDD). However, most studies on alcohol use and adverse MDD outcomes are conducted amongst MDD populations with (severe) alcohol use disorder in psychiatric treatment settings. Therefore, it remains unclear whether these results can be generalised to the general population. In light of this, we examined the longitudinal relationship between alcohol use and MDD persistence after a 3-year follow-up amongst people with MDD from the general population., Methods: Data were derived from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a psychiatric epidemiological prospective study comprising four waves amongst the adult Dutch general population ( n = 6.646). The study sample ( n = 642) consisted of those with 12-month MDD who participated at the follow-up wave. The outcome was 12-month MDD persistence after the 3-year follow-up, which was assessed via the Composite International Diagnostic Interview version 3.0. Weekly alcohol consumption was operationalised as non-drinking (0 drinks), low-risk drinking (⩽7 drinks; reference), at-risk drinking (women 8-13 drinks, men 8-20 drinks) and high-risk drinking (women ⩾14, men ⩾21 drinks). We performed univariate and multiple logistic regression analyses, which were adjusted for various socio-demographic and health-related factors., Results: The majority (67.4%) of the MDD sample were female, while the mean age was 47.1 years. Amongst these, 23.8% were non-drinkers, 52.0% were low-risk drinkers and 14.3% and 9.4% were at-risk and high-risk drinkers, respectively. Around one-quarter of the sample (23.6%) met the criteria for a persistent MDD after 3-year follow-up. No statistically significant association was found between alcohol use and MDD persistence, either for the crude model or the adjusted models. In comparison to low-risk drinking, the full adjusted model showed no statistically significant associations between MDD persistence and non-drinking (odds ratio (OR) = 1.15, p = 0.620), at-risk drinking (OR = 1.25, p = 0.423), or high-risk drinking (OR = 0.74, p = 0.501)., Conclusions: Contrary to our expectations, our findings showed that alcohol use was not a predictor of MDD persistence after 3-year follow-up amongst people with MDD from the general population.
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- 2023
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8. What makes the psychosis 'clinical high risk' state risky: psychosis itself or the co-presence of a non-psychotic disorder?
- Author
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Hasmi L, Pries LK, Ten Have M, de Graaf R, van Dorsselaer S, Bak M, Kenis G, Richards A, Lin BD, O'Donovan MC, Luykx JJ, Rutten BPF, Guloksuz S, and van Os J
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- Anxiety Disorders, Humans, Mood Disorders, Prospective Studies, Psychotic Disorders epidemiology, Schizophrenia epidemiology
- Abstract
Aims: Although attenuated psychotic symptoms in the psychosis clinical high-risk state (CHR-P) almost always occur in the context of a non-psychotic disorder (NPD), NPD is considered an undesired 'comorbidity' epiphenomenon rather than an integral part of CHR-P itself. Prospective work, however, indicates that much more of the clinical psychosis incidence is attributable to prior mood and drug use disorders than to psychosis clinical high-risk states per se. In order to examine this conundrum, we analysed to what degree the 'risk' in CHR-P is indexed by co-present NPD rather than attenuated psychosis per se., Methods: We examined the incidence of early psychotic experiences (PE) with and without NPD (mood disorders, anxiety disorders, alcohol/drug use disorders), in a prospective general population cohort (n = 6123 at risk of incident PE at baseline). Four interview waves were conducted between 2007 and 2018 (NEMESIS-2). The incidence of PE, alone (PE-only) or with NPD (PE + NPD) was calculated, as were differential associations with schizophrenia polygenic risk score (PRS-Sz), environmental, demographical, clinical and cognitive factors., Results: The incidence of PE + NPD (0.37%) was lower than the incidence of PE-only (1.04%), representing around a third of the total yearly incidence of PE. Incident PE + NPD was, in comparison with PE-only, differentially characterised by poor functioning, environmental risks, PRS-Sz, positive family history, prescription of antipsychotic medication and (mental) health service use., Conclusions: The risk in 'clinical high risk' states is mediated not by attenuated psychosis per se but specifically the combination of attenuated psychosis and NPD. CHR-P/APS research should be reconceptualised from a focus on attenuated psychotic symptoms with exclusion of non-psychotic DSM-disorders, as the 'pure' representation of a supposedly homotypic psychosis risk state, towards a focus on poor-outcome NPDs, characterised by a degree of psychosis admixture, on the pathway to psychotic disorder outcomes.
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- 2021
- Full Text
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