1. Paper-based electrochemical sensor for on-site detection of the sulphur mustard.
- Author
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Colozza N, Kehe K, Popp T, Steinritz D, Moscone D, and Arduini F
- Subjects
- Electrochemical Techniques, Electrodes, Hydrogen Peroxide, Limit of Detection, Biosensing Techniques, Mustard Gas, Nanoparticles
- Abstract
Herein, we report a novel paper-based electrochemical sensor for on-site detection of sulphur mustards. This sensor was conceived combining office paper-based electrochemical sensor with choline oxidase enzyme to deliver a sustainable sensing tool. The mustard agent detection relies on the evaluation of inhibition degree of choline oxidase, which is reversibly inhibited by sulphur mustards, by measuring the enzymatic by-product H
2 O2 in chronoamperometric mode. A nanocomposite constituted of Prussian Blue nanoparticles and Carbon Black was used as working electrode modifier to improve the electroanalytical performances. This bioassay was successfully applied for the measurement of a sulphur mustard, Yprite, obtaining a detection limit in the millimolar range (LOD = 0.9 mM). The developed sensor, combined with a portable and easy-to-use instrumentation, can be applied for a fast and cost-effective detection of sulphur mustards.- Published
- 2021
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