Search

Your search keyword '"Hepatoma -- Risk factors -- Research"' showing total 2 results
Start Over Descriptor "Hepatoma -- Risk factors -- Research" Journal environmental health perspectives
2 results on '"Hepatoma -- Risk factors -- Research"'

1. A reexamination of the PPAR-α activation mode of action as a basis for assessing human cancer risks of environmental contaminants

Author

Guyton, Kathryn Z., Chiu, Weihsueh A., Bateson, Thomas F., Jinot, Jennifer, Scott, Cheryl Siegel, Brown, Rebecca C., and Caldwell, Jane C.

Subjects
Pollutants -- Health aspects -- Research -- Physiological aspects, Cell receptors -- Physiological aspects -- Research -- Health aspects, Hepatoma -- Risk factors -- Research, Environmental issues, Health
Abstract

BACKGROUND:Diverseenvironmentalcontaminants, includingtheplasticizerdi(2-e ethylhexyl)phthalate (DEHP), are hepatocarcinogenic peroxisome proliferators in rodents. Peroxisome proliferator-activated receptor-α (PPAR-α) activation and its sequelae have been proposed to constitute a mode of action (MOA) for hepatocarcinogenesis [...]

Published
2009
Full Text
View/download PDF

2. Global burden of aflatoxin-induced liver cancer

Subjects
Aflatoxins -- Dosage and administration -- Complications and side effects, Hepatoma -- Risk factors -- Research, Environmental issues, Health
Abstract

Hepatocellular carcinoma (HCC), or liver cancer, is the third leading cause of cancer deaths worldwide, with prevalence in developing countries 16-32 times higher than in developed countries. Aflatoxin, a contaminant [...]

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results